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Cardiac Resynchronization Therapy

Phase 3

Heart Failure | Unknown | Cardiovascular |Abbott Laboratories|Last Updated: Feb 4, 2019

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLEDDMC
Total Trials1
Total Enrollment250

FDA Designations

No designations recorded

Clinical trial landscape

Cardiac Resynchronization Therapy · 1 trial · 1 indication

Phase 3 1
NCT00132977RethinQ Study - Evaluating Pacing in Heart Failure PatientsHeart Failure
COMPLETED250 Analytics
PHASE3COMPLETED
RethinQ Study - Evaluating Pacing in Heart Failure Patients
Heart FailureUnlock trial analytics

Study Endpoints

Primary Endpoints

Cardiac resynchronization therapy (CRT) effectiveness will be evaluated in terms of exercise capacity (peak VO2), as measured by cardiopulmonary exercise testing
6 months
Safety will be evaluated in terms of survival from CRT-D system-related complications.
6 months

Secondary Endpoints

Quality of Life Questionnaire
6 months
New York Heart Association (NYHA) Classification
6 months
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
Cardiac Resynchronization TherapyDEVICE -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites34

Inclusion Criteria: * Have an approved indication for implantation of an ICD. * Have advanced HF with a New York Heart Association (NYHA) Classification of III, despite receiving optimal pharmacological therapy. * Have a stable heart failure medical regimen. * Have a left ventricular ejection fract...

Countries:United States
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Frequently asked questions about Cardiac Resynchronization Therapy

What is Cardiac Resynchronization Therapy used for in heart failure?

Cardiac Resynchronization Therapy is a treatment evaluated for heart failure. It involves pacing to coordinate heart contractions and is being studied in patients with this condition. The therapy is currently in Phase 3 clinical development.

Who makes Cardiac Resynchronization Therapy?

Cardiac Resynchronization Therapy is developed by Abbott Laboratories, a company traded on the stock exchange under the ticker ABT. Abbott is conducting clinical research on this therapy for heart failure.

What phase is Cardiac Resynchronization Therapy in?

Cardiac Resynchronization Therapy is in Phase 3 clinical development. It is an investigational therapy for heart failure and has not been reported as approved by regulatory authorities.

What clinical trials is Cardiac Resynchronization Therapy in?

Cardiac Resynchronization Therapy is being studied in the RethinQ Study, identified as NCT00132977. This Phase 3 trial enrolled 250 participants with heart failure in the United States and has been completed.

Is Cardiac Resynchronization Therapy the same as cardiac pacing?

Cardiac Resynchronization Therapy is a form of pacing evaluated for heart failure. The RethinQ Study, NCT00132977, assessed pacing in heart failure patients, indicating that the therapy involves pacing as part of its approach.