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CVL-231 as IR formulation

Phase 1

Schizophrenia | Small molecule | Psychiatry |AbbVie Inc.|Last Updated: Apr 26, 2022

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment16
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05106309Pharmacokinetics of CVL-231 Following Single Oral Administration of Modified- and Immediate-release Formulations in Fasted and Fed Healthy ParticipantsPHASE1 COMPLETED 16Dec 1, 2021Feb 1, 2022Apr 26, 2022 -
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Study Design & Arms
Interventions
NameTypeDescription
10 mg CVL-231 as IR formulationDRUGTablets
30 mg CVL-231 as slow-release MR formulationDRUGCapsules
30 mg CVL-231 as medium release MR formulationDRUGCapsules
30 mg CVL-231 as fast release MR formulationDRUGCapsules
30 mg CVL-231 Target Release, FastedDRUGCapsules
30 mg CVL-231 Target Release, FedDRUGCapsules
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