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Sensei Biotherapeutics Announces Initiation of Strategic Review to Maximize Shareholder Value BOSTON

Key Takeaway: Sensei Biotherapeutics has announced the discontinuation of its solnerstotug development and is initiating a strategic review to explore alternatives for maximizing shareholder value. The company is considering several options, including asset sales, licensing, or potential mergers while planning a significant workforce reduction. The decision follows a careful evaluation of the company's pipeline and market conditions, and the future of its ongoing clinical trials now hangs in the balance.

Market Sentiment Analysis

POSITIVE FACTORS

  • The company has seen the therapeutic candidate solnerstotug demonstrate clinical activity.
  • The strategic review may lead to alternative opportunities for the company.

CONCERNS & RISKS

  • Discontinuation of development for solnerstotug.
  • Implementation of a workforce reduction to preserve cash.
  • No assurance that strategic alternatives will lead to an actual transaction.

Full Press Release Details

Sensei Biotherapeutics Announces Initiation of Strategic Review to Maximize Shareholder Value
BOSTON, October 30, 2025 (GLOBE NEWSWIRE) - Sensei Biotherapeutics, Inc. (Nasdaq: SNSE), a clinical-stage biotechnology company focused on the
discovery and development of next-generation therapeutics for cancer patients, today announced that its Board of Directors has determined, after extensive consideration of the Company's development pipeline and current market conditions, to
discontinue development of solnerstotug and initiate a comprehensive review of strategic alternatives aimed at maximizing shareholder value. The Company is exploring a range of strategic alternatives that may include, among other options, a sale of
assets, licensing arrangements, collaborations, a sale of the Company, a business combination, a merger, or an orderly wind-down of operations.
connection with this strategic review, the Company expects to implement a workforce reduction to preserve cash, the details of which will be disclosed separately. The Company plans to retain a small team of employees to assist in exploring strategic
alternatives, maintaining compliance with regulatory and financial reporting requirements, and managing the orderly cessation of development activities.
"We have seen solnerstotug demonstrate clinical activity in a patient population with significant unmet need," said John Celebi, President and
Chief Executive Officer of Sensei. "However, after careful review of future funding needs and the current capital markets environment, we have determined not to initiate a new clinical study. Our role now is to steward the Company and its
assets with care, including an orderly wind-down of the ongoing Phase 1/2 clinical trial and preservation of shareholder value."
not intend to provide updates on the strategic alternatives process unless and until its Board of Directors has approved a specific transaction or otherwise determines that disclosure is appropriate or required by law. The Company has not set a
definitive timeline for this process and there can be no assurance that the exploration of strategic alternatives will result in any transaction being announced or consummated.
About Sensei Biotherapeutics
Sensei Biotherapeutics
(Nasdaq: SNSE) is a clinical stage biotechnology company focused on the discovery and development of next-generation therapeutics for cancer patients. The Company is currently pursuing strategic alternatives to maximize shareholder value. For more
information, please visit www.senseibio.com.
Cautionary Note Regarding Forward-Looking Statements
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the
Private Securities Litigation Reform Act of 1995. These statements may be identified by words and phrases such as "believe", "designed to," "expect", "may", "plan", "potential",
"will", and similar expressions, and are based on Sensei's current beliefs and expectations. These forward-looking statements include expectations regarding the Company's strategic alternatives process, the entry into or
completion of any strategic alternative transaction, workforce reduction plans, and ability to maximize shareholder value. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in
such statements. Risks and uncertainties that may cause actual results to differ materially include
uncertainties inherent in strategic review processes, such as the risk that no suitable strategic alternative will be identified or consummated; risks associated with workforce reductions and
operational wind-down activities; risks regarding the Company's estimates of expenses and cash requirements; and other risks and uncertainties that are described in Sensei's Quarterly Report on Form
10-Q filed with the U.S. Securities and Exchange Commission (SEC) on August 5, 2025 and Sensei's other Periodic Reports filed with the SEC. Any forward-looking statements speak only as of the date
of this press release and are based on information available to Sensei as of the date of this release, and Sensei assumes no obligation to, and does not intend to, update any forward-looking statements, whether as a result of new information, future
events or otherwise.

Frequently Asked Questions

Why is Sensei Biotherapeutics discontinuing solnerstotug?

The Board decided to stop solnerstotug development after evaluating market conditions and funding needs.

What strategic alternatives is Sensei exploring?

Sensei is considering options like asset sales, licensing, mergers, or an orderly wind-down.

Will Sensei provide updates on their strategic review?

Sensei will only update stakeholders once a specific transaction is approved or legally required.

Is there a timeline for the strategic review process?

The Company has not established a definitive timeline for the strategic review process.

What will happen to Sensei's workforce?

The Company plans a workforce reduction to conserve cash while retaining a small team.

Last updated: Oct 30, 2025