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Faeth Therapeutics, Inc.

FTHFDA catalysts, PDUFA dates & pipeline intelligence
$10.65
▼ -2.7 · -20.22%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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Volume
767.13 K
Value Traded
8.77 M
Short % Float
14.84%
Days to Cover
6.3
-51.7%Week
-46.75%1 Month
-67.07%3 Month

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
275.24 M
EPS (TTM)
-8.18
P/E Ratio
-
Ent. Value
100.44 M
Total Shares
25.84 M
Float Shares
18.40 M
Insiders
28.82%
Institutions
51.95%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 data readout
PIKTOR
advanced endometrial cancer
Fast Track
Phase 2Small MoleculesOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

FTH Catalyst Timeline

Dated clinical, regulatory and corporate events for Faeth Therapeutics, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Faeth Therapeutics, Inc.

182Total events
8Upcoming
36Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T1Topline Readout
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PIKTOR
T2Trial Initiation
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PIKTOR

Event history 50

●R&D DayPresentation
Faeth management to participate in Guggenheim 3rd Annual Healthcare Innovation Conference (1x1 investor meetings)
▲Topline ReadoutPIKTORClinical Data
Faeth reports positive preliminary Phase 2 topline results for PIKTOR plus paclitaxel in advanced endometrial cancer
advanced endometrioid endometrial cancersource ↗
●R&D DayPIKTORPresentation
Faeth hosts webcast to discuss PIK-201 topline data
advanced endometrioid endometrial cancersource ↗
▲Primary Endpoint MetPIKTORClinical Data
PIKTOR plus paclitaxel achieved 33% confirmed ORR in efficacy-evaluable patients
advanced endometrioid endometrial cancersource ↗
●R&D DayPresentation
Webcast to discuss PIK-201 topline data
▲Safety Data UpdatePIKTORClinical Data
PIKTOR plus paclitaxel generally well tolerated with 5% treatment-related discontinuation rate
advanced endometrioid endometrial cancersource ↗
●Quarterly UpdateCorporate
Reported third quarter 2026 financial results for quarter ended September 30, 2026
●Management ChangeCorporate
Adam Schayowitz appointed to Faeth Board of Directors
●Poster PresentationPIKTORPresentation
Preclinical PIKTOR data presented in ESMO 2026 poster, including head-to-head vs gedatolisib
HR+/HER2- breast cancersource ↗
●Management ChangeCorporate
Karen Vousden, Ph.D. appointed to Board of Directors
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How FTH actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-11-09PIKTOR (PIK-201) Phase 2 topline data readout Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
2
Drugs Scored
rNPV / MCap
Top Drug
Top 63%
Micro Cap
(rank 421 of 667)
Percentile Rank
Showing 2 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Serabelisib Small MoleculesNCT07558733HR+ HER2- Breast CancerPhase 1/2 RECRUITING 32May 1, 2033
Sapanisertib Small MoleculesNCT06463028Endometrial CancerPhase 2 RECRUITING 40Sep 1, 2029
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every FTH program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
solnerstotug PD-(L)1 resistant tumorsPhase 1/22025-10-176 month PFS at 15 mg/kg: 50%; 6 month PFS at 3 mg/kg: 24%; overall 6 month PFS among 'hot tumor' patients: 37%; clinical responses at 15 mg/kg: 6; clinical responses in PD (L)1 resistant tumors: 5Read MoreSensei Biotherapeutics Reports New Clinical Results Highlighting Durable Progression Free Survival Data for Solnerstotug in PD-(L)1 Resistant Tumors at the ESMO Congress 2025 - 6-month progression-free survival (PFS) of Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
STEPHENSON BRIAN COfficer (Chief Financial Officer)Buy 4,400 46,088 held$23.40 07/01/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Avoro Capital Advisors LLC 0.3 % 36.10 M 1.44 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

FTH Short Interest

Shares sold short, counted twice a month.

14.84%
Short % of Float
of tradable shares sold short
2.7M
Shares Sold Short
+17.7% vs prior count
6.3 High
Days to Cover
trading days of normal volume to buy every short share back
432.5K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How FTH ranks across every disease it competes in

Competitive Position is a premium feature
See how FTH ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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FTH News

-FTH
Nov 11, 2026
FTHConferences/Events
▼ -20.2%today

Faeth Therapeutics to Participate in Upcoming November Investor Conferences

Faeth Therapeutics announced its participation in two upcoming investor conferences. The company will hold 1x1 meetings at the Guggenheim 3rd Annual Healthcare Innovation Conference and present at the Jefferies Global Healthcare Conference in London. Live webcasts of these events will be accessible on their website.

Read more →
-FTH
Nov 9, 2026
FTHPhases
▼ -42.5%on this newsshared move

Faeth Reports Positive Preliminary Phase 2 Topline Results from the PIK-201 Trial Evaluating PIKTOR in Combination with Paclitaxel in Patients with Advanced Endometrial Cancer

Faeth Therapeutics reported positive topline results from its Phase 2 trial of PIKTOR combined with paclitaxel for advanced endometrial cancer. The confirmed objective response rate was 33%, with a median progression-free survival of 7.4 months. The treatment was generally well tolerated, leading to plans for a Phase 3 trial.

Read more →
-FTH
Nov 6, 2026
FTHConferences/Events
▼ -42.5%on this newsshared move

Faeth to Report PIK-201 Phase 2 Data and Host Virtual Event on November 9, 2026

Faeth Therapeutics will host a virtual event on November 9, 2026, to discuss topline results from its Phase 2 PIK-201 trial for advanced endometrial cancer. The event will include insights from principal investigator David Starks and company management. PIKTOR, the investigational therapy, combines serabelisib and sapanisertib to target the PI3K/AKT/mTOR pathway.

Read more →
-FTH
Nov 5, 2026
FTHGeneral
▲ +10.7%on this news· ran to -36% by day 1shared move

Faeth Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Faeth Therapeutics announced the granting of options to three new employees, totaling 68,000 shares. The options, effective November 4, 2026, serve as an inducement under Nasdaq Listing Rule 5635(c)(4). The exercise price is set at $19.99 per share, aligning with the stock's closing price on the grant date.

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-FTH
Nov 3, 2026
FTHGeneral

Faeth Therapeutics Reports Third Quarter 2026 Financial Results and Operational Updates

Faeth Therapeutics reported its Q3 2026 financial results, highlighting the FDA's Fast Track designation for PIKTOR in advanced endometrial cancer. The company anticipates topline results from its Phase 2 PIK-201 trial by year-end. Financially, Faeth experienced a net loss of $20.4 million, up from $4.6 million in the same quarter last year.

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-FTH
Oct 27, 2026
FTHGeneral
▲ +13.5%on this news

Faeth Appoints Adam Schayowitz, Ph.D., MBA, Head of Research and Development at Zymeworks, to Board of Directors

Faeth Therapeutics appointed Dr. Adam Schayowitz to its Board of Directors. Dr. Schayowitz has nearly 20 years of experience in oncology drug development, having led numerous global programs. He will contribute to the advancement of Faeth's lead program, PIKTOR, in clinical trials for endometrial and breast cancer.

Read more →
-FTH
Oct 23, 2026
FTHPhases
▼ -15%on this newsshared move

Faeth Presents Updated Preclinical Data at ESMO, including First-Ever Head-to-Head Characterization of PIKTOR against Gedatolisib

Faeth Therapeutics presented promising preclinical data for PIKTOR at ESMO 2026, showing it inhibited tumor growth in breast cancer models effectively. PIKTOR outperformed gedatolisib and achieved complete tumor growth inhibition when combined with fulvestrant and palbociclib. The findings support ongoing trials, with interim data expected in 2027.

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-FTH
Oct 19, 2026
FTHConferences/Events

Faeth to Present Preclinical Data on PIKTOR in HR+/HER2- Breast Cancer Models at ESMO 2026

Faeth Therapeutics will present preclinical data on its investigational therapy PIKTOR at the ESMO Congress 2026. The data will showcase PIKTOR's efficacy as a monotherapy and in combination with other treatments for HR+/HER2- breast cancer. This presentation aims to inform the ongoing FTH-PIK-101 trial, with results from mouse models and cellular assays included.

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-FTH
Sep 17, 2026
FTHGeneral

Faeth Therapeutics Appoints Karen Vousden, Ph.D., to Board of Directors

Faeth Therapeutics has appointed Dr. Karen Vousden to its Board of Directors, effective September 11, 2026. Dr. Vousden has been instrumental in shaping the company's scientific direction and has served as a trusted advisor since its founding. Her expertise is expected to enhance the company's strategic initiatives in cancer treatment.

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-FTH
Sep 8, 2026
FTHConferences/Events

Faeth Therapeutics to Host Virtual KOL Event on Multi-Nodal Inhibition for the Treatment of Endometrial Cancer on October 6, 2026

Faeth Therapeutics has announced a virtual key opinion leader event scheduled for October 6, 2026. The event will feature Dr. Marcus Goncalves from NYU Langone Health, who will discuss the PAM pathway in relation to endometrial cancer. This initiative highlights the company's commitment to advancing cancer treatment through expert collaboration.

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-FTH
Sep 1, 2026
FTHConferences/Events
▲ +5.3%on this news· ran to +22% by day 3

Faeth Therapeutics to Participate in Upcoming September Investor Conferences

Faeth Therapeutics, a clinical-stage oncology company, has announced its participation in two upcoming investor conferences. The events include the Wells Fargo 21st Annual Healthcare Conference and the Citi Biopharma Back to School Summit. This engagement aims to showcase their lead program, PIKTOR, and connect with potential investors.

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-FTH
Aug 17, 2026
FTHFDA Updates

Faeth Therapeutics Announces FDA Grant of Fast Track Designation for PIKTOR Plus Paclitaxel in Biomarker-Selected Advanced Endometrial Cancer

Faeth Therapeutics has received Fast Track designation from the FDA for its PIKTOR combination therapy, which includes sapanisertib and serabelisib with paclitaxel. This designation is specifically for treating patients with advanced or recurrent endometrial cancer that have specific genetic alterations. The Fast Track status aims to expedite the development and review process for this promising treatment.

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-FTH
Aug 14, 2026
FTHGeneral
▲ +13.3%on this newsshared move

Faeth Therapeutics Strengthens Executive Team with Senior Leadership Appointments

Faeth Therapeutics has announced the appointment of Deepak Tiwari as Senior Vice President of Technical Operations and Matt Biegler as Senior Vice President of Investor Relations. These appointments are part of the company's strategy to strengthen its leadership team in preparation for upcoming clinical milestones related to its PIKTOR program.

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-FTH
Aug 7, 2026
FTHConferences/Events

Faeth Therapeutics to Present PK/PD Modeling That Informed PIKTOR Dose Selection in Ongoing FTH-PIK-201 Trial at Upcoming Scientific Conference

Faeth Therapeutics will present important PK/PD modeling data for its investigational drug PIKTOR at the upcoming STOP Cancer conference. This data will inform the dose selection for the ongoing FTH-PIK-201 trial. The conference is scheduled for August 7-8, 2026, in New York, highlighting the company's commitment to oncology research.

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-FTH
Aug 4, 2026
FTHGeneral
▼ -6.7%on this newsshared move

Faeth Therapeutics Reports Second Quarter 2026 Financial Results and Operational Updates

Faeth Therapeutics announced its financial results for the second quarter of 2026, showcasing key corporate achievements and future milestones. The CEO, Anand Parikh, emphasized the significance of their recent collaboration with Sensei Biotherapeutics. This partnership is viewed as a pivotal moment for the company's growth and development in oncology.

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About Faeth Therapeutics, Inc.

Austin, TX 29 employees faeththerapeutics.com
Headquarters701 TILLERY STREET #12 #1010, AUSTIN, TX, 78702
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