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Gastrointestinal Cancer: one US-listed biotech with a clinical-stage programme

OncologyUncontestedData as of 2026-09-04

Competitors1in the clinic
Median market cap$6.1Buniverse median $1.20B
Allocated capital$1.5B$6.1B competing
Phase 3 or filed01 mid, 0 early
Pure plays0this indication only
Capital rank117/299crowding rank 137

Gastrointestinal Cancer is uncontested. Cogent Biosciences (COGT) is the only US-listed developer in the $100M to $20B band running a clinical programme here, with Bezuclastinib in phase 2.

There is no public comparable to price it against. COGT spreads its $6.1B market cap across 4 indications, so $1.5B of it is allocated here.

Nothing here has reached Phase 3: 1 programme in mid stage and 0 in early stage, so the field is still several years from a first approval.

$1.5B of allocated capital sits in Gastrointestinal Cancer, ranking it 117th of 299 indications by the money committed to it.

Companies developing drugs for Gastrointestinal Cancer 1

TickerCompanyLead assetPhaseTrialsMarket capPure playIndicationsNext catalyst
COGTCogent BiosciencesBezuclastinibPhase 21$6.1BNo4 30 Nov 2026

Sorted by phase, then by market capitalisation. Ticker links open the company profile.

Why Gastrointestinal Cancer counts as uncontested

Uncontested. One US-listed developer in the size band is running a clinical programme here, so there is no public comparable to price it against.

The map splits indications on two folds: six or more competitors counts as crowded, and a median company above $1.20B counts as richly priced. Gastrointestinal Cancer has one competitor and a median of $6.1B.

Oncology

Oncology holds $187B of the map's capital, 27.8% of the total, spread across 119 indications and 103 companies. 34 of those indications have more than one company competing.

See every Oncology indication on the map

Related indications in Oncology

Intrahepatic Cholangiocarcinoma1 company · $1.5B · median $6.1BUncontestedSystemic Mastocytosis1 company · $1.5B · median $6.1BUncontestedDesmoid Tumor1 company · $1.5B · median $3.1BUncontestedSoft-tissue Sarcoma2 companies · $1.5B · median $4.0BConcentrated betUrothelial Cancer1 company · $1.4B · median $1.4BUncontestedNon-Hodgkin's Lymphoma7 companies · $1.7B · median $239MKnife fightMetastatic Small Cell Lung Cancer1 company · $1.3B · median $4.0BUncontestedAdvanced Renal Cell Carcinoma1 company · $1.3B · median $14.7BUncontested

Gastrointestinal Cancer pipeline questions

Which biotech companies are developing drugs for Gastrointestinal Cancer?

Cogent Biosciences (COGT, Bezuclastinib, Phase 2). Those are the 1 US-listed developer in the $100M to $20B market cap band with a clinical-stage programme in Gastrointestinal Cancer.

How advanced is the Gastrointestinal Cancer pipeline?

Of the 1 clinical-stage programme in Gastrointestinal Cancer, 0 are in Phase 3 or filed, 1 is in mid-stage development and 0 are in early-stage development.

Is anyone else developing a drug for Gastrointestinal Cancer?

No. COGT is the only US-listed company in the $100M to $20B market cap band with a clinical-stage programme in Gastrointestinal Cancer, which is why the indication is classified as uncontested.

When is the next Gastrointestinal Cancer catalyst?

The next dated catalyst in Gastrointestinal Cancer is COGT on 30 Nov 2026. 1 dated event across the field fall in the next 12 months.

How this page is built

  • Universe is US-listed drug developers with a $100M to $20B market capitalisation, identified by SEC SIC code 2833, 2834 or 2836 or by a pharmaceutical or biotechnology industry classification, less a reviewed exclusion list of contract research organisations, device and diagnostics makers and diversified generics manufacturers.
  • An asset attributed to three or more different companies is treated as shared standard of care rather than any one company’s programme and excluded. Pembrolizumab alone appears under 21 tickers in raw trial data.
  • A programme counts only where at least one industry-sponsored trial supports it, so investigator-initiated academic studies of third-party drugs are excluded.

Allocated capital divides each company’s market capitalisation evenly across the indications it is running clinical programmes in, so every dollar of the universe is counted exactly once. Total market capitalisation competing counts a company in each of its indications and therefore sums to more than the universe.

Third-party market size estimates are not used anywhere on this page. Approved incumbents are excluded from competitor counts, and companies above $20B are outside the universe by construction.

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