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VIR-2482

Phase 1

Influenza A | Small molecule | Infectious Disease |Vir Biotechnology, Inc.|Last Updated: Jun 9, 2022

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment100

FDA Designations

No designations recorded

Clinical trial landscape

VIR-2482 · 1 trial · 1 indication

Phase 1 1
NCT04033406Study of VIR-2482 in Healthy VolunteersInfluenza A
COMPLETED100 Analytics
PHASE1COMPLETED
Study of VIR-2482 in Healthy Volunteers
Influenza AUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of participants with treatment-emergent adverse events.
Up to 12 months post-dose
Number of participants with abnormalities in vital signs.
Up to 12 months post-dose
Number of participants with abnormalities in electrocardiogram (ECG).
Up to 12 months post-dose
Number of participants with abnormalities in clinically significant laboratory findings.
Up to 12 months post-dose

Secondary Endpoints

Concentrations of VIR-2482 in serum
Up to 12 months post-dose
Incidence of anti-drug antibody (ADA) to VIR-2482
Up to 12 months post-dose
Titers (if applicable) of anti-drug antibody (ADA) to VIR-2482
Up to 12 months post-dose
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
VIR-2482EXPERIMENTALVIR-2482
PlaceboPLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
VIR-2482DRUGVIR-2482 given by intramuscular injection
PlaceboDRUGSterile normal saline (0.9% NaCl) given by intramuscular injection
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Eligibility Criteria

Age Range18 Years to 64 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy Male or Female age 18 to \< 65 years * Body mass index (BMI) of 18.0 kg/m\^2 to 32.0kg/m\^2 Exclusion Criteria: * Any clinically significant chronic or acute medical condition that makes the volunteer unsuitable for participation * History of influenza-like illness o...

Countries:Australia
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Frequently asked questions about VIR-2482

What is VIR-2482 used for?

VIR-2482 is an investigational small molecule being developed for the prevention or treatment of Influenza A. It is currently in Phase 1 clinical development, meaning it has not yet been approved by regulatory authorities and is still being studied for safety and efficacy in clinical trials.

What does VIR-2482 target?

VIR-2482 is a small molecule designed to target Influenza A. The specific molecular target has not been disclosed, but the drug is being studied for its ability to address Influenza A infections. It is in Phase 1 development by Vir Biotechnology.

Who makes VIR-2482?

VIR-2482 is being developed by Vir Biotechnology, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol VIR. The company is conducting clinical research on this investigational drug for Influenza A.

What phase is VIR-2482 in?

VIR-2482 is in Phase 1 clinical development. It is an investigational drug, meaning it is not yet approved by the FDA or other regulatory agencies. The drug is being studied for Influenza A and has completed one Phase 1 trial.

What clinical trials is VIR-2482 in?

VIR-2482 has one completed clinical trial, NCT04033406, titled 'Study of VIR-2482 in Healthy Volunteers.' This Phase 1 trial enrolled 100 participants in Australia and was a randomized, double-blind, placebo-controlled study. The trial has been completed, and no active trials are currently listed.

Is VIR-2482 the same as any other drug?

VIR-2482 is not known to have alternative names. It is a unique investigational small molecule developed by Vir Biotechnology for Influenza A. No other names or aliases have been associated with this drug in the available clinical trial information.