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PD-217, 014

Phase 2

Irritable Bowel Syndrome | Small molecule | Gastrointestinal |Pfizer, Inc.|Last Updated: Jun 17, 2008

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment330

FDA Designations

No designations recorded

Clinical trial landscape

PD-217, 014 · 1 trial · 1 indication

Phase 2 1
NCT00139672A Study To Investigate The Effect Of PD-217,014 On Abdominal Pain/Discomfort In Patients With IBS.Irritable Bowel Syndrome
COMPLETED330 Analytics
PHASE2COMPLETED
A Study To Investigate The Effect Of PD-217,014 On Abdominal Pain/Discomfort In Patients With IBS.
Irritable Bowel SyndromeUnlock trial analytics

Study Endpoints

Primary Endpoints

Assess the effect of PD-217,014 on the relief of abdominal pain/discomfort in patients with irritable bowel syndrome. Primary endpoint is a responder, defined by having adequate relief for > or = 50% of the active treatment period (4 weeks).

Secondary Endpoints

Assess the effect of PD-217,014 on the patient's global assessment of IBS symptoms, stool frequency & consistency and on abdominal bloating (change from baseline to week 4).
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
PD-217,014DRUG -
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Eligibility Criteria

Age Range18 Years to 75 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Males and females having Irritable bowel syndrome as defined by the Rome II criteria. * Patients must have had normal examination of colon anatomy within the last 5 years Exclusion Criteria: * Patient with an organic gastrointestinal disease. * Patients with poor renal funct...

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Frequently asked questions about PD-217, 014

What is PD-217,014 used for?

PD-217,014 is an investigational small molecule being studied for the treatment of Irritable Bowel Syndrome (IBS). It is being developed by Pfizer, Inc. (PFE) and has completed a Phase 2 clinical trial, but it is not yet approved and remains in clinical development.

What does PD-217,014 target?

The molecular target of PD-217,014 has not been disclosed in available information. It is a small molecule being investigated for its effect on abdominal pain and discomfort in patients with Irritable Bowel Syndrome, but its specific mechanism of action is not publicly detailed.

Who makes PD-217,014?

PD-217,014 is being developed by Pfizer, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is currently in clinical development for Irritable Bowel Syndrome and has completed a Phase 2 trial.

What phase is PD-217,014 in?

PD-217,014 is in Phase 2 clinical development. It has completed one Phase 2 trial for Irritable Bowel Syndrome, and it is not FDA approved. The drug remains investigational and has not yet progressed to later-stage trials or regulatory submission.

What clinical trials is PD-217,014 in?

PD-217,014 has one completed clinical trial, registered as NCT00139672. This Phase 2 study investigated the effect of PD-217,014 on abdominal pain and discomfort in 330 patients with Irritable Bowel Syndrome. The trial was randomized and double-blind, and it is no longer active.

Is PD-217,014 the same as any other drug?

No alternative names for PD-217,014 have been disclosed. The drug is known only by its development code, PD-217,014, and is being studied by Pfizer for Irritable Bowel Syndrome. No other names or brand names have been associated with this compound in available information.