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Surface antigen inactivated influenza vaccine

Phase 2

Influenza | Monoclonal antibody | Infectious Disease |Novartis AG|Last Updated: Dec 1, 2016

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment129

FDA Designations

No designations recorded

Clinical trial landscape

Surface antigen inactivated influenza vaccine · 1 trial · 1 indication

Phase 2 1
NCT00518453Immunogenicity of a Surface Antigen, Inactivated Influenza Vaccine Formulation 2007-2008Influenza
COMPLETED129 Analytics
PHASE2COMPLETED
Immunogenicity of a Surface Antigen, Inactivated Influenza Vaccine Formulation 2007-2008
InfluenzaUnlock trial analytics

Study Endpoints

Primary Endpoints

evaluate the antibody response to each influenza vaccine antigen
21 days post-immunization

Secondary Endpoints

Safety and tolerability of the study vaccine in the study population
Throughout the study
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Arm 1: FluvirinEXPERIMENTAL -

Interventions

NameTypeDescription
Surface antigen inactivated influenza vaccineBIOLOGICAL1 dose of Fluvirin 2007/2008 Northern Hemisphere vaccine composition
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Eligibility Criteria

Age Range18 Years to 84 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy Subjects eligible for enrollment into this study are male and female adult volunteers Exclusion Criteria: * Any serious disease

Countries:United Kingdom
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Frequently asked questions about Surface antigen inactivated influenza vaccine

What is Surface antigen inactivated influenza vaccine used for?

Surface antigen inactivated influenza vaccine is used for influenza, a viral infection of the respiratory tract. It is an investigational vaccine being developed to provide immunity against seasonal influenza strains. The vaccine is currently in clinical development and has not been approved for public use.

Who makes Surface antigen inactivated influenza vaccine?

Surface antigen inactivated influenza vaccine is being developed by Novartis AG, a multinational pharmaceutical company listed on the New York Stock Exchange under the ticker symbol NVS. The company conducted a Phase 2 clinical trial to evaluate the vaccine's immunogenicity in healthy adults.

What phase is Surface antigen inactivated influenza vaccine in?

Surface antigen inactivated influenza vaccine is in Phase 2 clinical development. It is an investigational vaccine, meaning it has not yet received regulatory approval. The Phase 2 trial, which has been completed, assessed the vaccine's ability to generate an immune response in healthy volunteers.

What clinical trials is Surface antigen inactivated influenza vaccine in?

Surface antigen inactivated influenza vaccine has one completed clinical trial, registered as NCT00518453. This Phase 2 study, titled "Immunogenicity of a Surface Antigen, Inactivated Influenza Vaccine Formulation 2007-2008," enrolled 129 participants in the United Kingdom. The trial evaluated the vaccine's immunogenicity in healthy adults aged 18 years and older.

How does Surface antigen inactivated influenza vaccine work?

Surface antigen inactivated influenza vaccine works by presenting inactivated surface antigens from influenza viruses to the immune system. This exposure triggers an immune response, including the production of antibodies, which can recognize and neutralize the virus upon future exposure. The vaccine is designed to protect against seasonal influenza strains.