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Johnson & Johnson

JNJFDA catalysts, PDUFA dates & pipeline intelligence
$271.04
▲ +5.11 · +1.9%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
Quarterly Cash
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52W LOW $184.6652W HIGH $281.07
Volume
6.40 M
Value Traded
2.34 B
Short % Float
0.7%
Days to Cover
2.0
+1.28%Week
+1.3%1 Month
+5.95%3 Month
+17.92%6 Month
+36.78%5 Year
+37,394.82%All Time

Cash Data

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Key Stats

Market Cap
653.18 B
EPS (TTM)
6.68
P/E Ratio
40.58
Ent. Value
680.60 B
Total Shares
2.41 B
Float Shares
2.40 B
Insiders
0.12%
Institutions
77.34%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 1b data readout
pasritamig
advanced prostate cancer patients who have progressed after multiple lines of therapy (combination with JNJ-9401)
Phase 1bBiologicsOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

JNJ Catalyst Timeline

Dated clinical, regulatory and corporate events for Johnson & Johnson

Catalyst Timeline

Dated clinical, regulatory & corporate events for Johnson & Johnson

2112Total events
34Upcoming
1057Tier-1 (high impact)
2010 to 2027Coverage

Upcoming catalysts 2

T1PDUFA Date
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IMAAVY™Approved
T2Timing Guidance
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Event history 50

▲Oral PresentationAmivantamabApprovedPresentation
Cohort 5 OrigAMI-4 first-line HNSCC data presented as rapid oral presentation at ESMO Congress 2026 (Abstract #1539RO)
recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)source ↗
▲Oral PresentationPresentation
Cohort 5 first-line HNSCC data presented as rapid oral presentation at ESMO Congress 2026 (Abstract #1539RO)
recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)source ↗
▲Topline ReadoutClinical Data
Cohort 5 of OrigAMI-4 shows 77% confirmed ORR in first-line HNSCC (non-HPV OPSCC)
recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)source ↗
▲Dose Finding UpdateJNJ-6143Trial
50-mg once-daily dose of JNJ-6143 selected as preliminary optimal dose for further development
advanced prostate cancer (mAPMR/mCRPC)source ↗
▲Topline ReadoutJNJ-6143Clinical Data
Phase 1 results for JNJ-6143 show 75% tumor response rate in advanced prostate cancer
advanced prostate cancer (mAPMR/mCRPC)source ↗
▲Topline ReadoutApalutamideApprovedClinical Data
PROTEUS substudy results: perioperative apalutamide plus ADT vs surgery alone
high-risk localised or locally advanced prostate cancersource ↗
▲Primary Endpoint MetApalutamideApprovedClinical Data
PROTEUS substudy met primary EFS endpoint with 62% reduction in risk of recurrence or death vs surgery alone
high-risk localized or locally advanced prostate cancersource ↗
▲Secondary Endpoint DataApalutamideApprovedClinical Data
PROTEUS substudy showed 51% lower risk of metastasis or death (MFS) with perioperative apalutamide plus ADT
high-risk localized or locally advanced prostate cancersource ↗
▲Late-BreakerApalutamideApprovedPresentation
PROTEUS substudy results presented as late-breaking abstract at ESMO Congress 2026 (#LBA53)
high-risk localized or locally advanced prostate cancersource ↗
▲Oral PresentationJNJ-6143Presentation
JNJ-6143 Phase 1 data presented in Proffered Paper session at ESMO Congress 2026
advanced prostate cancer (mAPMR/mCRPC)source ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How JNJ actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-08-28Stelara (ustekinumab) PDUFA Date ApprovedPDUFA
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
92
Drugs Scored
rNPV / MCap
Top Drug
Top 1%
Large Pharma
(rank 8 of 657)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Sep 2026; product lines: last four quarters to Sep 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
DARZALEX
TREMFYA
INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA
ERLEADA
STELARA
Xarelto
CARVYKTI
IMBRUVICA
Simponi/Simponi Aria
OPSUMIT/OPSYNVI
SPRAVATO
UPTRAVI
Top 12 of 22 product lines shown.
Showing 91 of 835 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Icotrokinra Small moleculeNCT06878404Arthritis, PsoriaticPhase 3 ACTIVE NOT_RECRUITING 1,302Feb 4, 2028
JNJ-77242113 Small moleculeNCT06295692Generalized Pustular PsoriasisPhase 3 ACTIVE NOT_RECRUITING 19Oct 14, 2027
Icotrokinra Small moleculeNCT07196748Colitis, UlcerativePhase 3 RECRUITING 882Jan 13, 2032
Icotrokinra Small moleculeNCT07196722Crohn DiseasePhase 2 RECRUITING 1,092Oct 16, 2032
Milvexian Small moleculeNCT05757869Atrial FibrillationPhase 3 ACTIVE NOT_RECRUITING 20,284Dec 8, 2026
Milvexian Small moleculeNCT05702034Ischemic Stroke; Ischemic Attack, TransientPhase 3 ACTIVE NOT_RECRUITING 12,523Oct 15, 2026
Ramantamig Small moleculeNCT07589634Multiple MyelomaPhase 3 RECRUITING 1,230Nov 8, 2030
JNJ-79635322 Small moleculeNCT07266441Multiple MyelomaPhase 3 ACTIVE NOT_RECRUITING 1,544Dec 12, 2028
JNJ-79635322 Small moleculeNCT05652335Relapsed or Refractory Multiple MyelomaPhase 1 RECRUITING 180Nov 15, 2030
JNJ-78934804 Small moleculeNCT07577856Colitis, UlcerativePhase 3 RECRUITING 644Oct 16, 2030
JNJ-78934804 Small moleculeNCT07577843Crohn DiseasePhase 3 RECRUITING 460Jul 12, 2030
Amivantamab Monoclonal antibodyNCT06662786Colorectal NeoplasmsPhase 3 RECRUITING 1,700Jan 20, 2032
Pasritamig Monoclonal antibodyNCT07164443Metastatic Castration-resistant Prostatic NeoplasmsPhase 3 RECRUITING 1,203Aug 18, 2028
Amivantamab Monoclonal antibodyNCT06385080Squamous Cell Carcinoma of Head and NeckPhase 3 RECRUITING 787Jul 28, 2033
Amivantamab Monoclonal antibodyMarketedNCT05488314Lung Non-Small Cell CarcinomaPhase 3 ACTIVE NOT_RECRUITING 3,040Apr 28, 2027
Pasritamig Small moleculeNCT07225946Prostatic Neoplasms, Castration-ResistantPhase 3 RECRUITING 800Jun 7, 2030
Amivantamab Monoclonal antibodyMarketedNCT02609776Non-Small-Cell Lung CancerPhase 1 ACTIVE NOT_RECRUITING 751Dec 31, 2027
Amivantamab Monoclonal antibodyNCT05379595Advanced or Metastatic Colorectal CancerPhase 1 RECRUITING 225May 11, 2031
Amivantamab Monoclonal antibodyMarketedNCT05845671Lung CancerPhase 1 ACTIVE NOT_RECRUITING 12Jan 1, 2028
Amivantamab Monoclonal antibodyMarketedNCT04606381NeoplasmsPhase 1 ACTIVE NOT_RECRUITING 158Apr 1, 2027
Pasritamig Small moleculeNCT05818683Metastatic Castration-resistant Prostate NeoplasmsPhase 1 RECRUITING 300May 23, 2028
JNJ-78278343 Small moleculeNCT04898634Prostatic NeoplasmsPhase 1 ACTIVE NOT_RECRUITING 711Mar 31, 2027
Pasritamig Small moleculeNCT07319871Prostatic NeoplasmsPhase 1 RECRUITING 40Apr 30, 2027
Botaretigene sparoparvovec Gene therapyNCT06646289X-Linked Retinitis PigmentosaPhase 3 ACTIVE NOT_RECRUITING 226Oct 24, 2030
Botaretigene sparoparvovec Gene therapyNCT05926583Retinitis PigmentosaPhase 3 ACTIVE NOT_RECRUITING 4Nov 12, 2030
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every JNJ program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
JNJ-6143 advanced prostate cancerPhase 12026-10-25tumor response rate: 75%; psa reduction 50 percent: 77%; psa reduction 90 percent: 48%Read MoreJohnson & Johnson reports 75% tumor response rate in advanced prostate cancer with JNJ-6143, a first-in-class RIPTAC™ moleculeRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Schmid TimothyOfficer (EVP, WW Chair, MedTech)Option 11,070 36,517 held$131.94 09/02/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
TRI LOCUM PARTNERS LP 13.3 % (-6.3 %) 107.92 M 424.94 K 2.52% ( 10.44 K)
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Shares held by hedge funds each quarter, and who bought or sold.

JNJ Institutional Ownership Trends

JNJ Short Interest

Shares sold short, counted twice a month.

0.7%
Short % of Float
of tradable shares sold short
16.8M
Shares Sold Short
-24.0% vs prior count
2.0 Low
Days to Cover
trading days of normal volume to buy every short share back
8.5M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-30
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How JNJ ranks across every disease it competes in

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See how JNJ ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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JNJ News

JNJ
Oct 27, 2026
JNJConferences/Events
▲ +1.9%today

Johnson & Johnson to Host Enterprise Business Review

Johnson & Johnson will host an Enterprise Business Review on December 8, 2026, for investors. The event will cover the Innovative Medicine and MedTech sectors, featuring insights from company leaders on growth strategies and product innovations. Attendees can expect presentations, product demonstrations, and Q&A sessions.

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JNJ
Oct 25, 2026
JNJPhases
▲ +1.9%today

RYBREVANT FASPRO™ (amivantamab and hyaluronidase-lpuj) combination demonstrates 77% overall response rate in first-line treatment of patients with advanced head and neck cancer

Johnson & Johnson reported a 77% overall response rate for RYBREVANT FASPRO in first-line treatment of advanced head and neck cancer. The study showed deep and durable responses, with 65% ongoing at the clinical cutoff. These results support the ongoing Phase 3 OrigAMI-5 study and highlight the dual-targeting approach's effectiveness.

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JNJ
Oct 25, 2026
JNJPhases
▲ +1.9%today

Johnson & Johnson reports 75% tumor response rate in advanced prostate cancer with JNJ-6143, a first-in-class RIPTAC™ molecule

Johnson & Johnson announced promising Phase 1 results for JNJ-6143, showing a 75% tumor response rate in advanced prostate cancer patients. In the study, 77% of patients achieved a PSA reduction of at least 50%. The results suggest a potential new treatment option for patients with limited options due to disease progression.

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JNJ
Oct 24, 2026
JNJPhases

Johnson & Johnson announces ERLEADA® (apalutamide) treatment before and after surgery reduces risk of recurrence or death by 62% versus surgery alone in high-risk localised or locally advanced prostate cancer

Johnson & Johnson announced that apalutamide plus hormone therapy significantly reduces the risk of recurrence or death by 62% compared to surgery alone in high-risk localized prostate cancer. The PROTEUS substudy showed a 51% lower risk of metastasis or death over time. These findings were presented at the ESMO Congress 2026.

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JNJ
Oct 24, 2026
JNJPhases

Johnson & Johnson announces ERLEADA® (apalutamide) treatment before and after surgery reduces risk of recurrence or death by 62% versus surgery alone in high-risk prostate cancer

Johnson & Johnson announced that its treatment ERLEADA® (apalutamide) significantly reduces the risk of recurrence or death by 62% in high-risk prostate cancer patients compared to surgery alone. The Phase 3 PROTEUS substudy also indicated a 51% lower risk of metastasis. These findings were presented at the ESMO Congress 2026.

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JNJ
Oct 23, 2026
JNJFDA Updates

European Commission approves Johnson & Johnson’s TECVAYLI®▼ (teclistamab) monotherapy for relapsed/refractory multiple myeloma, expanding treatment options from first relapse

The European Commission has approved Johnson & Johnson's TECVAYLI® (teclistamab) monotherapy for adult patients with relapsed/refractory multiple myeloma. This approval is based on Phase 3 results showing a 71% reduction in disease progression risk and a 40% reduction in mortality risk compared to standard care. Teclistamab is now available as a second-line treatment option.

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JNJ
Oct 22, 2026
JNJGeneral

Johnson & Johnson Reports First Real-World VARIPULSE Pro Platform Data and 12-Month OMNYPULSE Platform Outcomes for Atrial Fibrillation Treatment at APHRS 2026

Johnson & Johnson presented promising data on its VARIPULSE Pro and OMNYPULSE platforms at APHRS 2026. The VARIPULSE Pro showed 100% acute procedural success with a 0.4% adverse event rate. Meanwhile, the OMNYPULSE platform demonstrated an 82.5% success rate in preventing atrial arrhythmia recurrence at 12 months. Both platforms aim to enhance atrial fibrillation treatment.

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JNJ
Oct 20, 2026
JNJGeneral

Johnson & Johnson Launches Next-Generation Shockwave™ C2 Aero Fly Coronary IVL Catheter, Cutting IVL Treatment Time in Half

Johnson & Johnson has launched the Shockwave C2 Aero Fly Coronary IVL Catheter, which cuts treatment time for coronary artery disease in half. This next-generation device delivers pulses at 2 Hz, enhancing efficiency and reducing ischemic time for patients. The catheter builds on the features of its predecessor, offering improved deliverability and repositioning capabilities.

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JNJ
Oct 19, 2026
JNJPhases

Johnson & Johnson announces new TREMFYA® (guselkumab) data showing durable 3-year outcomes in moderate to severe Crohn’s disease and expanding evidence in perianal fistula

Johnson & Johnson announced new data on TREMFYA® (guselkumab) showing impressive three-year outcomes for patients with moderate to severe Crohn's disease. The Phase 3 GALAXI studies revealed a clinical remission rate of 94% and endoscopic remission of 52%. Additionally, the FUZION study indicated maintained fistula remission, highlighting guselkumab's long-term efficacy and safety in managing Crohn's disease.

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JNJ
Oct 19, 2026
JNJPhases

Johnson & Johnson announces new data showing TREMFYA® (guselkumab) is the only IL-23 to deliver durable fistula remission through 48 weeks in Crohn's disease with perianal fistula

Johnson & Johnson has announced new data from the Phase 3 FUZION study, demonstrating that TREMFYA (guselkumab) is the only IL-23 inhibitor to achieve durable fistula remission in Crohn's disease over 48 weeks. The study showed an increase in combined fistula remission rates from 28% at Week 24 to 35% at Week 48 for the 100 mg dose group. These findings reinforce the drug's efficacy and safety profile in treating this challenging condition.

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JNJ
Oct 16, 2026
JNJFDA Updates

CHMP recommends approval of Johnson & Johnson’s TALVEY®▼ (talquetamab) plus daratumumab in earlier line treatment of relapsed/refractory multiple myeloma

The CHMP has recommended the approval of Johnson & Johnson's TALVEY® (talquetamab) in combination with daratumumab for treating relapsed/refractory multiple myeloma. This recommendation is based on promising Phase 3 trial results, which demonstrated significant improvements in both progression-free survival and overall survival rates. The combination therapy uniquely targets myeloma cells while minimizing impact on healthy immune cells, marking a potential advancement in treatment options.

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JNJ
Oct 13, 2026
JNJGeneral
▼ -5.7%on this newsshared move

Johnson & Johnson Announces Quarterly Dividend for Fourth Quarter 2026

Johnson & Johnson has announced a quarterly cash dividend of $1.34 per share for the fourth quarter of 2026. This dividend will be payable on December 8, 2026, to shareholders on record as of November 24, 2026. The announcement underscores the company's commitment to returning value to its shareholders.

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JNJ
Oct 13, 2026
JNJGeneral
▼ -5.7%on this newsshared move

Johnson & Johnson reports Q3 2026 results, raises 2026 guidance

Johnson & Johnson reported a 5.9% increase in third-quarter sales for 2026, reaching $25.4 billion. The company raised its full-year guidance, anticipating reported sales of $101.2 billion and adjusted EPS of $11.10. Despite a significant drop in net earnings due to litigation charges and acquisitions, the firm highlighted strong operational performance and notable innovations in medical technology and pharmaceuticals.

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JNJ
Oct 12, 2026
JNJPhases
▼ -5.7%on this newsshared move

TREMFYA® (guselkumab) demonstrated sustained clinical and endoscopic remission through 3 years in moderately to severely active Crohn's disease

Johnson & Johnson announced promising results from the Phase 3 GALAXI studies, showing that TREMFYA (guselkumab) maintains clinical and endoscopic remission in adults with moderately to severely active Crohn's disease over three years. The data revealed high remission rates, with 94% of patients achieving clinical remission and 88% maintaining corticosteroid-free remission. The findings underscore the drug's potential for long-term disease management.

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JNJ
Oct 12, 2026
JNJPhases
▼ -5.7%on this newsshared move

New TREMFYA® (guselkumab) study shows consistent perianal fistula remission across key Crohn's disease patient subgroups

Johnson & Johnson announced new Phase 3 data for TREMFYA (guselkumab), showing consistent perianal fistula remission in adults with Crohn's disease. The findings, presented at the ACG 2026 Annual Meeting, indicate efficacy across various patient subgroups, including those with prior biologic exposure. TREMFYA achieved remission rates of 28% compared to 10% for placebo. This trial marks a significant advancement in treating this challenging condition.

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JNJ
Oct 9, 2026
JNJPhases

New Johnson & Johnson ICOTYDE® (icotrokinra) long-term data demonstrate robust 2-year results in the treatment of adults and adolescents with plaque psoriasis

Johnson & Johnson has announced promising two-year results from its Phase 3 ICONIC-LEAD study of ICOTYDE (icotrokinra) for treating moderate-to-severe plaque psoriasis in adults and adolescents. The data, presented at the Fall Clinical Dermatology conference, showed that nearly 75% of patients achieved clear or almost clear skin, with a consistent safety profile and no new safety concerns. These results highlight ICOTYDE's potential as a transformative treatment option.

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JNJ
Oct 2, 2026
JNJPhases

Johnson & Johnson announces new ICOTYDE® (icotrokinra) data in difficult-to-treat plaque psoriasis with proven durability through 2-years, affirming its use as a powerful first line systemic therapy

Johnson & Johnson announced positive results from the Phase 3 ICONIC-TOTAL study for ICOTYDE (icotrokinra), demonstrating its effectiveness in treating plaque psoriasis over two years. The study showed significant skin clearance in patients with high-impact psoriasis sites, with no new safety concerns. This positions ICOTYDE as a promising first-line systemic therapy.

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JNJ
Oct 1, 2026
JNJGeneral

New Global Survey by Johnson & Johnson Finds Most Women Don’t Connect Eye Health Changes with Menopause

Johnson & Johnson's new survey reveals that while most women understand menopause affects mood and sleep, only 40% associate it with changes in eye health. The survey highlights a significant gap in awareness, with many women not seeking necessary eye care. The company, alongside Naomi Watts and the American Optometric Association, aims to encourage women to prioritize eye health during midlife.

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JNJ
Sep 29, 2026
JNJPhases

Johnson & Johnson presents new data reinforcing sustained disease control and improved daily function achieved with IMAAVY® (nipocalimab-aahu) in generalized myasthenia gravis (gMG)

Johnson & Johnson has announced new data on IMAAVY (nipocalimab-aahu) for treating generalized myasthenia gravis (gMG), highlighting sustained disease control and improved patient outcomes over a two-year period. The findings indicate significant improvements in daily functioning and muscle strength, along with a reduction in corticosteroid use. Additionally, a survey revealed that many patients previously dissatisfied with their treatment experienced positive results after switching to IMAAVY.

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About Johnson & Johnson

New Brunswick, NJ 140,800 employees jnj.com
HeadquartersONE JOHNSON & JOHNSON PLZ, NEW BRUNSWICK, NJ, 08933
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