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Inhibrx Biosciences, Inc.

INBXFDA catalysts, PDUFA dates & pipeline intelligence
$88.61
▼ -4.77 · -5.11%

Financials

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52W LOW $53.3952W HIGH $155.29
Volume
251.17 K
Value Traded
30.61 M
Short % Float
31.32%
Days to Cover
11.8
-1.31%Week
-12.88%1 Month
+7.47%3 Month
-32.59%6 Month
+500.95%5 Year
+358.46%All Time

Cash Data

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Key Stats

Market Cap
1.30 B
EPS (TTM)
-9.39
P/E Ratio
-
Ent. Value
1.34 B
Total Shares
14.72 M
Float Shares
10.96 M
Insiders
25.55%
Institutions
87.96%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 1/2 data presentation
ozekibart (INBRX-109)
Ewing sarcoma, adolescents and adults
Phase 1/2Antibody-Drug Conjugates (ADCs)Oncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

INBX Catalyst Timeline

Dated clinical, regulatory and corporate events for Inhibrx Biosciences, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Inhibrx Biosciences, Inc.

95Total events
22Upcoming
37Tier-1 (high impact)
2024 to 2027Coverage

Upcoming catalysts 2

T2Timing Guidance
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INBRX-106
T1Topline Readout
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INBRX-106

Event history 50

◆Oral PresentationINBRX-106Presentation
Webcast presentation to provide primary endpoint results from Phase 2 portion of HexAgon study
Head and Neck Squamous Cell Carcinoma (HNSCC)source ↗
●R&D DayPresentation
Inhibrx hosts live webcast presentation to discuss Phase 2 HexAgon results
▲Topline ReadoutINBRX-106Clinical Data
Primary endpoint results from randomized Phase 2 portion of HexAgon study of INBRX-106 plus pembrolizumab in first-line HNSCC
PD-L1 positive (CPS ≥ 20) metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC)source ↗
▲Primary Endpoint MetINBRX-106Clinical Data
INBRX-106 plus pembrolizumab met primary endpoint with 48.3% cORR vs 26.5% for pembrolizumab alone
PD-L1 positive (CPS ≥ 20) metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC)source ↗
▲Primary Endpoint MetINBRX-106Clinical Data
INBRX-106 plus pembrolizumab met primary endpoint with 48.3% cORR vs 26.5% for pembrolizumab alone in Phase 2 HexAgon study
head and neck squamous cell carcinoma (HNSCC)source ↗
▲Debt Royalty FinancingCorporate
Amended Loan Agreement with Oxford Finance, expanding total facility to $500.0 million
◆Trial InitiationINBRX-106Trial
Phase 3 portion of HexAgon study to begin in Q3 2026
first-line Head and Neck Squamous Cell Carcinoma (HNSCC)source ↗
▲Debt Royalty FinancingCorporate
Oxford Loan Amendment providing additional $325.0 million
◆Topline ReadoutINBRX-106Clinical Data
Plans to announce PFS data from randomized Phase 2 trial in HNSCC
head and neck squamous cell carcinoma (HNSCC)source ↗
●BLA SubmissionINBRX-109FiledRegulatory Filing
BLA submission for ozekibart in unresectable or metastatic conventional chondrosarcoma
conventional chondrosarcomasource ↗
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Past FDA Catalysts and PDUFA Decisions

How INBX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-25ordastobart (INBRX-106) Phase 2 data presentation Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
3
Drugs Scored
rNPV / MCap
Top Drug
Top 43%
Micro Cap
(rank 283 of 657)
Percentile Rank
Showing 5 of 6 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
INBRX-109 Small moleculeNCT03715933Ewing SarcomaPhase 1 RECRUITING 411Jun 1, 2029
INBRX-109 Small moleculeNCT04950075Conventional ChondrosarcomaNDA/BLA ACTIVE NOT_RECRUITING 206Dec 1, 2026
INBRX-106 Small moleculeNCT06295731Head and Neck Squamous Cell Carcinoma (HNSCC)Phase 2 ACTIVE NOT_RECRUITING 410May 1, 2029
INBRX-106 Small moleculeNCT04198766Solid TumorPhase 1 RECRUITING 340Jul 1, 2033
INBRX-101/rhAAT-Fc Small moleculeCompletedNCT03815396Alpha-1 Antitrypsin DeficiencyPhase 1 COMPLETED 31Aug 18, 2022
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Clinical Trial Results

Readouts, endpoints and source filings for every INBX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
INBRX-106 head and neck squamous cell carcinomaPhase 22026-09-08c ORR combination: 48.3%; c ORR control: 26.5%; median PFS combination: 9.6 months; median PFS control: 4.9 months; six month PFS combination: 72.4%; six month PFS control: 42.8%; HPV positive c ORR combination: 80.0%; HPV positive c ORR control: 33.3%; HPV positive CR combination: 30.0%; HPV positive CR control: 0%; HPV positive six month PFS combination: 90.0%; HPV positive six month PFS control: 33.0%Read MoreInhibrx's INBRX-106 Nearly Doubles Response Rate and Achieves Interim Median PFS of 9.6 months in Phase 2 HNSCC Study First OX40 agonist to demonstrate clinical benefit in a randomized study INBRX-106 plus pembrolizumab delivers a 48.3% cORR and 72.4% of patients...Read More
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Inside Trades

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InsiderSideSharesPriceValueDate
Lappe MarkDirector, Officer (Chief Executive Officer)Buy 2,470 743,018 held$84.07 10/14/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
PERCEPTIVE ADVISORS LLC 1.8 % (-5.3 %) 122.96 M 1.30 M -10.05% ( -144.94 K)
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INBX Institutional Ownership Trends

INBX Short Interest

Shares sold short, counted twice a month.

31.32%
Short % of Float
of tradable shares sold short
3.4M
Shares Sold Short
+1.2% vs prior count
11.8 Very high
Days to Cover
trading days of normal volume to buy every short share back
290.4K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

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Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Put Vol
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Real-Time Option Chain

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Competitive positioning

How INBX ranks across every disease it competes in

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INBX News

INBX
Oct 13, 2026
INBXConferences/Events

Inhibrx Announces Participation in Upcoming Scientific Conferences

Inhibrx Biosciences, Inc. has announced its participation in several upcoming scientific conferences, including the ESMO Congress and the MSTS Annual Meeting. The presentations will focus on their investigational therapies, such as the OX40 agonist ordastobart and the DR5 agonist ozekibart. These events highlight Inhibrx's commitment to advancing its clinical pipeline.

Read more →
INBX
Sep 8, 2026
INBXPhases
▼ -5.6%on this news

Inhibrx's INBRX-106 Nearly Doubles Response Rate and Achieves Interim Median PFS of 9.6 months in Phase 2 HNSCC Study

Inhibrx announced promising results from its Phase 2 study of INBRX-106 combined with pembrolizumab for head and neck squamous cell carcinoma. The combination achieved a confirmed objective response rate of 48.3% and a median progression-free survival of 9.6 months, significantly outpacing pembrolizumab alone. The company plans to expand the study to support potential accelerated approval.

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INBX
Sep 4, 2026
INBXConferences/Events
▼ -5.6%on this newsshared move

Inhibrx To Host Webcast Presentation to Provide Primary Endpoint Results for INBRX-106 Phase 2 First-Line HNSCC Study

Inhibrx Biosciences will host a live webcast on September 8, 2026, to present primary endpoint results from the Phase 2 HexAgon study of INBRX-106. This study evaluates the safety and efficacy of INBRX-106 in combination with pembrolizumab for first-line treatment of PD-L1 positive metastatic or unresectable recurrent Head and Neck Squamous Cell Carcinoma. Investors can join via a web link or phone.

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INBX
Aug 13, 2026
INBXFDA Updates
▼ -8.9%on this news

Inhibrx Reports Second Quarter 2026 Financial Results

Inhibrx Biosciences, Inc. reported its financial results for Q2 2026, highlighting significant funding and ongoing clinical trials. The company secured an additional $325 million through a loan amendment and is preparing to announce progression-free survival data from its Phase 2 trial in head and neck cancer. Despite these advancements, Inhibrx faced a net loss of $36.7 million and reported no revenue for the quarter.

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INBX
Jul 16, 2026
INBXGeneral

Inhibrx Announces Amended Loan Agreement with Oxford Finance, Expanding Total Facility to $500.0 Million

Inhibrx Biosciences has amended its loan agreement with Oxford Finance, increasing its credit facility to $500 million. This includes a $100 million immediate funding and the potential for an additional $225 million. The funding aims to support the development of Inhibrx's clinical pipeline, including candidates INBRX-109 and INBRX-106.

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INBX
Jun 15, 2026
INBXFDA Updates

Inhibrx Announces U.S. FDA Acceptance of BLA for Ozekibart in Patients with Conventional Chondrosarcoma No filing review issues identified by FDA with PDUFA goal date set for

Inhibrx has announced that the FDA accepted its Biologics License Application for ozekibart, which targets conventional chondrosarcoma, a rare and aggressive bone cancer. The FDA has not identified any issues with the filing, setting a goal date for decision on April 14, 2027. If approved, ozekibart would be the first systemic treatment available for patients with unresectable or metastatic forms of this cancer. The application is backed by positive trial results, indicating significant benefits in progression-free survival compared to placebo.

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INBX
May 14, 2026
INBXGeneral

Inhibrx Reports First Quarter 2026 Financial Results

Inhibrx Biosciences reported its financial results for Q1 2026, highlighting ongoing clinical trials for INBRX-106 and ozekibart. The company announced an increase in cash reserves and plans to release key trial data later in the year. However, it also reported a net loss and rising interest expenses.

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INBX
May 11, 2026
INBXPhases
▼ -5%on this news· ran to -19% by day 1shared move

Inhibrx Reports Interim Phase 2 Data for INBRX-106 in First-Line HNSCC; Initial Results Demonstrate Potential Costimulatory Benefit Over PD-1 Monotherapy

Inhibrx Biosciences announced positive interim results from the Phase 2 HexAgon study evaluating INBRX-106 in combination with pembrolizumab for first-line HNSCC. The combination arm showed a 22.6% increase in confirmed responses compared to the control. The treatment demonstrated robust T-cell activation and a manageable safety profile. The company plans to initiate Phase 3 trials in Q3 2026.

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INBX
May 8, 2026
INBXConferences/Events
▲ +7.9%on this newsshared move

Inhibrx To Host Webcast Presentation to Provide Clinical Update on INBRX-106 HexAgon Study in First Line HNSCC

Inhibrx Biosciences will host a live webcast on May 11, 2026, to present interim results from the Phase 2 HexAgon study. This study evaluates the safety and efficacy of INBRX-106 in combination with pembrolizumab for first-line treatment of PD-L1 positive metastatic or unresectable recurrent Head and Neck Squamous Cell Carcinoma. The webcast will be accessible for 60 days after the event.

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INBX
Apr 21, 2026
INBXPhases

Inhibrx Provides Clinical Update on Ozekibart (INBRX-109) in Late Line Colorectal Cancer

Inhibrx has provided an update on its Phase 1/2 study of ozekibart (INBRX-109) for colorectal cancer, revealing a 20% objective response rate and a median progression-free survival of 5.5 months. The drug demonstrated a manageable safety profile, with common side effects being mild. Inhibrx plans to discuss further development with the FDA, including potential first-line trials.

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INBX
Apr 20, 2026
INBXConferences/Events
▼ -6.6%on this news· ran to +36% by day 3shared move

Inhibrx To Host Webcast Presentation to Provide Clinical Update on Ozekibart (INBRX-109) in Late Line Colorectal Cancer

Inhibrx Biosciences will host a live webcast on April 21, 2026, to provide a clinical update on ozekibart (INBRX-109) in patients with advanced colorectal cancer. The presentation will discuss results from a Phase 1/2 study evaluating ozekibart in combination with FOLFIRI. Ozekibart has previously received Fast Track and orphan drug designations from the FDA for chondrosarcoma.

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INBX
Mar 19, 2026
INBXGeneral
▼ -5.6%on this newsshared move

Inhibrx Reports Fourth Quarter and Fiscal Year 2025 Financial Results

Inhibrx Biosciences reported its financial results for Q4 and fiscal year 2025, revealing a net loss of $32.8 million in Q4. The company has two ongoing clinical trials and plans to submit a Biologics License Application for ozekibart in early Q2 2026. Financial management appears to improve with reduced R&D and G&A expenses.

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INBX
Mar 2, 2026
INBXConferences/Events

Inhibrx Announces Participation in Upcoming Scientific Conference

Inhibrx Biosciences, Inc. announced its participation in the ESMO Sarcoma and Rare Cancers Congress scheduled for March 12-14, 2026, in Lugano, Switzerland. The company will present a Phase 1 study of its DR5 agonist Ozekibart combined with Irinotecan and Temozolomide for treating Ewing Sarcoma. The presentation will be accessible via Inhibrx's investor website.

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INBX
Dec 16, 2025
INBXPhases

Inhibrx Biosciences Provides Progress Updates on the INBRX-106 Program and the Expansion Cohorts of the ozekibart (INBRX-109) Program

Inhibrx Biosciences provided updates on its INBRX-106 and ozekibart programs, highlighting progress in clinical trials for head and neck squamous cell carcinoma and non-small cell lung cancer. The company is nearing completion of patient enrollment in these trials and anticipates data maturity in 2026. Additionally, ozekibart's combination therapies have shown positive outcomes, with plans for FDA discussions regarding accelerated approval.

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INBX
Nov 14, 2025
INBXGeneral
▲ +6%on this news

Inhibrx Reports Third Quarter 2025 Financial Results

Inhibrx reported a net loss of $35.3 million for the third quarter of 2025. The company held $153.1 million in cash and cash equivalents at the end of the period. Ozekibart met its primary endpoint in a chondrosarcoma trial, prompting plans for a regulatory submission in 2026.

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INBX
Oct 23, 2025
INBXPhases
▲ +102%on this news· ran to +172% by day 3

Inhibrx Biosciences Reports Positive Topline Results from its Registrational Trial of Ozekibart (INBRX-109) in Chondrosarcoma and Provides Updates on Colorectal Cancer and Ewing Sarcoma Expansion Cohorts

Inhibrx Biosciences reported positive topline results from its ChonDRAgon study, showing that ozekibart significantly improves median progression-free survival in patients with advanced chondrosarcoma. The study met its primary endpoint, demonstrating a 52% reduction in disease progression risk. Additionally, promising updates were shared regarding expansion cohorts for colorectal cancer and Ewing sarcoma, indicating potential for broader application of ozekibart.

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INBX
Oct 22, 2025
INBXConferences/Events
▼ -16%on this news· ran to +57% by day 3shared move

Inhibrx To Host Webcast Presentation of Topline Results from its Registrational Trial of Ozekibart (INBRX-109) in Chondrosarcoma and to Provide Updates on Colorectal Cancer and Ewing Sarcoma Expansion Cohorts

Inhibrx Biosciences, Inc. is set to host a live webcast on October 23, 2025, to present topline results from its registrational trial of ozekibart (INBRX-109) in patients with unresectable chondrosarcoma. The company will also provide updates on ongoing expansion trials for ozekibart in combination therapies for colorectal cancer and Ewing sarcoma. This presentation marks a key milestone in the clinical development of Inhibrx's product pipeline, highlighting its focus on innovative cancer treatments.

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INBX
Aug 13, 2025
INBXGeneral

Inhibrx Reports Second Quarter 2025 Financial Results

Inhibrx reported a net loss of $28.7 million for the second quarter of 2025. Cash and cash equivalents stood at $186.6 million as of June 30. Revenue reached $1.3 million, up from $0.1 million in the prior year period. The company expects data readouts for its two clinical programs later this year.

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INBX
May 14, 2025
INBXGeneral

Inhibrx Reports First Quarter 2025 Financial Results

Inhibrx Biosciences, Inc. reported its first quarter financial results for 2025, showcasing an increased cash balance following a successful financing round. The company now oversees two clinical programs, with expected data readouts for chondrosarcoma and colorectal cancer within this year. Research and development expenses decreased significantly compared to the previous year, while total operating expenses were also reduced. However, Inhibrx reported a net loss of $43.3 million for the quarter, highlighting persistent financial challenges as it continues to develop its clinical pipeline.

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About Inhibrx Biosciences, Inc.

La Jolla, CA 110 employees inhibrx.com
Headquarters11025 N. TORREY PINES ROAD, SUITE 140, LA JOLLA, CA, 92037
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