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Inhibrx Reports Third Quarter 2025 Financial Results

Key Takeaway: Inhibrx Biosciences reported its third-quarter financial results for 2025, highlighting positive topline outcomes from its ozekibart trial in chondrosarcoma. Following a significant corporate restructuring, the company now operates with two clinical programs. Inhibrx plans to submit a biologics license application to the FDA in the second quarter of 2026.
Price reaction · baseline $74.62 (2025-11-13 close) · hit pre-market · clean, no other INBX news in the window
day 0 close
+6%
day 1
+3.7%
day 3 · peak
+10.1%

Market Sentiment Analysis

POSITIVE FACTORS

  • Inhibrx reported positive topline results for ozekibart in chondrosarcoma.
  • The company has two programs in ongoing clinical trials.
  • Inhibrx is advancing its therapeutic candidates towards FDA submission.

CONCERNS & RISKS

  • The company faces uncertainties regarding the accuracy of topline data.
  • There are risks associated with the timing and results of clinical trials.
  • Financial performance may be affected by market conditions.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+279%
120-day peak, hindsight
Typical move
3%
average across 2 past catalysts
Cash runway
~13 mo
Low dilution risk
Lead asset
Pembrolizumab
Phase 2 · Triple Negative Breast Cancer

Full Press Release Details

SAN DIEGO,Nov. 14, 2025/PRNewswire/ -- Inhibrx Biosciences, Inc. (Nasdaq:INBX) ("Inhibrx" or the "Company") today reported financial results for the third quarter of 2025. Following the completion of the sale of INBRX-101 (the "101 Transaction") by Inhibrx, Inc. (the "Former Parent") to Sanofi S.A. and the Former Parent's concurrent spin-off of the Inhibrx business in May 2024, the biopharmaceutical company now has two programs in ongoing clinical trials.

Recent Corporate Highlights

On October 23, 2025, Inhibrx announced positive topline results from its registrational trial of ozekibart (INBRX-109) in chondrosarcoma and provided an update on its colorectal cancer and Ewing sarcoma expansion cohorts.

Financial Results

About Inhibrx Biosciences, Inc.

Inhibrx is a clinical-stage biopharmaceutical company with a pipeline of novel biologic therapeutic candidates. Inhibrx utilizes diverse methods of protein engineering to address the specific requirements of complex target and disease biology, including its proprietary protein engineering platforms. Inhibrx was incorporated in January 2024 as a direct, wholly-owned subsidiary of Inhibrx, Inc. Prior to the sale of Inhibrx, Inc. and the INBRX-101 program to Sanofi S.A., Inhibrx acquired certain corporate infrastructure and other assets and liabilities through a series of internal restructuring transactions effected by Inhibrx, Inc. Inhibrx, Inc. also completed a distribution to holders of its shares of common stock of 92% of the issued and outstanding shares of Inhibrx. Following such transactions, Inhibrx's current clinical pipeline of therapeutic candidates includes ozekibart (INBRX-109) and INBRX-106, both of which utilize multivalent formats where the precise valency can be optimized in a target-centric way to mediate what Inhibrx believes to be the most appropriate agonist function. For more information, please visitwww.inhibrx.com.

Forward Looking Statements

Inhibrx cautions you that statements contained in this press release regarding matters that are not historical facts are forward-looking statements. These statements are based on Inhibrx's current beliefs and expectations. These forward-looking statements include, but are not limited to, statements regarding statements regarding the safety and efficacy of its therapeutic candidate, ozekibart, based on topline and interim results; the potential for ozekibart to be used for the treatment of chondrosarcoma, colorectal cancer and Ewing sarcoma; any presumption that topline, interim or preliminary data will be representative of final data or data in later clinical trials; and Inhibrx's plans to submit it to the U.S. Food and Drug Administration a biologics license application in the second quarter of 2026. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in Inhibrx's business, including, without limitation, risks and uncertainties regarding: topline data may not accurately reflect the complete results of a particular study or trial and remain subject to audit, and final data may differ materially from topline data; the initiation, timing, progress and results of its preclinical studies and clinical trials, and its research and development programs; its ability to advance therapeutic candidates into, and successfully complete, clinical trials; its interpretation of topline, interim or preliminary data from its clinical trials, including interpretations regarding disease control and disease response; the Company's ability to utilize the Company's technology platform to generate and advance additional therapeutic candidates; the implementation of the Company's business model and strategic plans for the Company's business and therapeutic candidates; the scope of protection the Company is able to establish and maintain for intellectual property rights covering the Company's therapeutic candidates; the ability to raise funds needed to satisfy the Company's capital requirements, which may depend on financial, economic and market conditions and other factors, over which the Company may have no or limited control; the Company's financial performance; developments relating to the Company's competitors and the Company's industry; regulatory review and approval of the Company's therapeutic candidates; and other risks described from time to time in the "Risk Factors" section of its filings with the SEC, including those described in its Annual Report on Form 10-K, its Quarterly Reports on Form 10-Q, and supplemented from time to time by its Current Reports on Form 8-K as filed from time to time. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and Inhibrx undertakes no obligation to update these statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

Investor and Media Contact:

Kelly D. DeckChief Financial Officer[email protected]858-795-4260
Inhibrx Biosciences, IncCondensed Consolidated Statements of Operations(In thousands, except per share data)(Unaudited)
THREE MONTHS ENDEDSEPTEMBER 30, NINE MONTHS ENDEDSEPTEMBER 30,
2025 2024 2025 2024
Revenue:
License fee revenue $                      — $                      — $                 1,300 $                    100
Total revenue 1,300 100
Operating expenses:
Research and development 28,535 38,893 87,679 170,376
General and administrative 5,277 7,904 17,723 111,244
Total operating expenses 33,812 46,797 105,402 281,620
Loss from operations (33,812) (46,797) (104,102) (281,520)
Total other income (expense) (1,444) 2,933 (3,117) 2,016,959
Provision for income taxes 2 2
Net income (loss) $             (35,256) $             (43,864) $          (107,221) $         1,735,437
Earnings (loss) per share
Basic $                 (2.28) $                 (2.84) $                 (6.93) $              119.04
Diluted $                 (2.28) $                 (2.84) $                 (6.93) $              117.09
Shares used in computing earnings (loss)per share
Basic 15,478 15,468 15,471 14,578
Diluted 15,478 15,468 15,471 14,821
Inhibrx Biosciences, IncCondensed Consolidated Balance Sheets(In thousands)(Unaudited)
SEPTEMBER 30, DECEMBER 31,
2025 2024
Cash and cash equivalents $                             153,088 $                             152,596
Other current assets 8,335 7,802
Non-current assets 16,048 20,369
Total assets $                             177,471 $                             180,767
Current liabilities $                               35,983 $                               40,730
Long-term debt, net 99,917
Other non-current liabilities 4,741 6,453
Total liabilities 140,641 47,183
Stockholders' equity 36,830 133,584
Total liabilities and stockholders' equity $                             177,471 $                             180,767

Frequently Asked Questions

What were the key highlights from Inhibrx's Q3 2025 report?

Inhibrx reported positive topline results for ozekibart in chondrosarcoma and has two ongoing clinical programs.

When does Inhibrx plan to submit its FDA application?

Inhibrx plans to submit a biologics license application to the FDA in the second quarter of 2026.

What is ozekibart being tested for?

Ozekibart is being tested for the treatment of chondrosarcoma, colorectal cancer, and Ewing sarcoma.

What challenges does Inhibrx face moving forward?

Inhibrx faces uncertainties regarding clinical trial results and financial performance influenced by market conditions.

Last updated: Nov 14, 2025