Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
isolated perfusion · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| Melphalan Administration PHP | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| isolated perfusion | DRUG | - |
| melphalan | DRUG | - |
DISEASE CHARACTERISTICS: * Histologically or cytologically confirmed hepatic malignancy * Unresectable disease * Disease predominantly in the parenchyma of the liver * One of the following primary tumor histologies: * Adenocarcinoma of gastrointestinal or other origin * Neuroendocri...
| Company | Ticker | Trials | Lead Phase | Drugs |
|---|---|---|---|---|
| GE Healthcare Technologies Inc. | GEHC | 1 | PHASE1 | GEH200520/ GEH200521- Part A |
| Zimmer Biomet Holdings, Inc. | ZBH | 1 | - | Undisclosed |
| Ascentage Pharma Group International Unsponsored ADR | AAPG | 1 | PHASE1 | Olverembatinib |
Isolated perfusion is used for treating cancer, specifically unresectable liver cancer. It is an investigational therapy being studied in oncology. The treatment involves hepatic arterial infusion of melphalan with hepatic perfusion in patients with unresectable liver cancer.
Isolated perfusion is being developed by Delcath Systems, Inc., a company traded under the ticker symbol DCTH. The company is conducting clinical research on this therapy for cancer treatment.
Isolated perfusion is in Phase 2 clinical development. It is an investigational therapy and has not been approved by the FDA. The therapy is still undergoing clinical trials to evaluate its safety and effectiveness for treating unresectable liver cancer.
Isolated perfusion has one completed clinical trial, identified as NCT00096083. This Phase 2 trial studied hepatic arterial infusion of melphalan with hepatic perfusion in treating patients with unresectable liver cancer. The trial enrolled 56 participants in the United States.
Yes, isolated perfusion is classified as a small molecule therapy. It is being studied in the oncology therapeutic area for the treatment of cancer, specifically unresectable liver cancer.