Approval Probability
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Adjusted LOA
ML Risk
Sildenafil · 1 trial · 1 indication
To evaluate and compare the impact of 2 grams of Sildenafil Cream 3.6%, Placebo Cream and Vehicle Cream on vulvar blood flow, as assessed by thermography in normal healthy premenopausal women.
| Arm | Type | Description |
|---|---|---|
| Sildenafil Cream, 3.6% | ACTIVE_COMPARATOR | Contains both Sildenafil and L-arginine |
| Placebo Cream | PLACEBO_COMPARATOR | Contains L-arginine, no Sildenafil |
| Vehicle Cream | OTHER | Contains no L-arginine, no Sildenafil |
| Name | Type | Description |
|---|---|---|
| Sildenafil | DRUG | Sildenafil Cream, 3.6% |
| Vehicle | DRUG | No Active or experimental ingredients |
| Placebo | DRUG | Cream with only L-arginine |
Inclusion Criteria: * Subject must be a premenopausal woman at least 18 years of age. * Subject must be willing to avoid high protein meals and follow dietary guidance provided by the study site staff for the duration of the study. * Women of childbearing potential must be using an acceptable form ...