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BIIB028

Phase 1

Advanced Solid Tumors | Small molecule | Oncology |Biogen Inc.|Last Updated: Jan 9, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment43
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00725933Administration of BIIB028 to Subjects With Solid TumorsPHASE1 COMPLETED 43Jun 1, 2008Oct 1, 2011Jan 9, 20173 United States
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Study Endpoints
Primary Endpoints
Safety and Tolerability of BIIB028
As specified in Protocol
Secondary Endpoints
PK and PD of BIIB028
As specified in protocol
Antitumor activity
As specified in protocol
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Interventions
NameTypeDescription
BIIB028DRUGIV infusion administered twice weekly until disease progression or unacceptable toxicity
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: * Ability to understand the purpose and risks of the study and provide signed and dated informed consent and authorization to use protected health information (PHI) in accordance with national and local subject privacy regulations. * Age greater than or equal to 18 years at the ...

Countries:United States
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