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AZD7762

Phase 1

Solid Tumors | Small molecule | Oncology |AstraZeneca PLC|Last Updated: Dec 6, 2010

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment42

FDA Designations

No designations recorded

Clinical trial landscape

AZD7762 · 1 trial · 1 indication

Phase 1 1
NCT00413686Study to Assess Safety of AZD7762 Administered Alone and in Combination With Gemcitabine in Patients With Advanced Solid MalignanciesSolid Tumors
COMPLETED42 Analytics
PHASE1COMPLETED
Study to Assess Safety of AZD7762 Administered Alone and in Combination With Gemcitabine in Patients With Advanced Solid Malignancies
Solid TumorsUnlock trial analytics

Study Endpoints

Primary Endpoints

To assess the safety and tolerability of AZD7762 alone and in combination with Gemcitabine
Assessed after each course of treatment

Secondary Endpoints

To determine the single-dose (after the first single-agent dose) and combination-dose (afer the 2nd combination dose) pharmacokinetics (PK) of AZD7762.
Assessed after each course of treatment
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALAZD7762 monotherapy followed by AZD7762 + gemcitabine

Interventions

NameTypeDescription
AZD7762DRUGintravenous infusion
GemcitabineDRUGweekly intravenous infusion
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Histologically or cytologically confirmed malignancy that is metastatic or unresectable and for which standard curative or palliative measures do not exist or are no longer effective * ECOG performance status of 0 or 1 * Patient and tumor type must be suitable for treatment wi...

Countries:United States
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Competitive Landscape -Other Solid Tumors 9 trials (matched to "Solid Tumors")

Frequently asked questions about AZD7762

What is AZD7762 used for?

AZD7762 is an investigational small molecule being studied for the treatment of solid tumors. It is in Phase 1 clinical development and has been evaluated in a completed clinical trial involving patients with advanced solid malignancies.

Who makes AZD7762?

AZD7762 is being developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker symbol AZN.

What phase is AZD7762 in?

AZD7762 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed.

What clinical trials is AZD7762 in?

AZD7762 has been studied in one completed Phase 1 clinical trial, identified as NCT00413686. This trial assessed the safety of AZD7762 administered alone and in combination with gemcitabine in patients with advanced solid malignancies.

Is AZD7762 FDA approved?

AZD7762 is not FDA approved. It is an investigational drug that has completed a Phase 1 clinical trial, but it remains in clinical development and has not received regulatory approval.