Recent Updates
Recently added Catalysts

ARGX-117

Phase 2

Delayed Graft Function | Monoclonal antibody | Other |argenx SE|Last Updated: Mar 18, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment103
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05907096ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft FunctionPHASE2 ACTIVE NOT_RECRUITING 103Feb 17, 2024Jul 31, 2026Mar 18, 202645 United States, Australia +9
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
eGFR at 24 weeks posttransplant
Up to 24 weeks

Estimated glomerular filtration rate

Secondary Endpoints
Proportion of participants with Delayed Graft Function (DGF)
Up to 52 weeks
Proportion of participants with fDGF
Up to 52 weeks
Duration of dialysis treatment for DGF within the first 30 days posttransplant
up to 30 days
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
ARGX-117EXPERIMENTALPatients receiving ARGX-117 intravenous infusions
PlaceboPLACEBO_COMPARATORPatients receiving placebo intravenous infusions
Interventions
NameTypeDescription
ARGX-117BIOLOGICALIntravenous administration of ARGX-117
PlaceboOTHERIntravenous administration of placebo
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 70 Years
SexALL
Healthy VolunteersNo
Study Sites45

Inclusion Criteria: * Is at least the local legal age of consent for clinical studies and at least aged 18 years and less than 70 years * Agree to use contraceptive measures consistent with local regulations * Are diagnosed with ESRD and have been stable on chronic dialysis for at least 3 months * ...

Countries:United StatesAustraliaAustriaBelgiumBrazilCanadaFranceItalyPortugalSpainSweden
Unlock Eligibility Criteria
Recent Changes (Last 90 Days)
LOWMay 26, 2026NCT05907096primaryCompletionDate: changed
LOWMay 24, 2026NCT05907096studyFirstPostDate: changed