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Xalatan

Phase 2

Open-Angle Glaucoma | Small molecule | Cardiovascular |Alcon Inc.|Last Updated: Jul 29, 2008

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment150
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00465621Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular HypertensionPHASE2 COMPLETED 150Mar 1, 2007 -Jul 29, 20081 United States
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Study Endpoints
Primary Endpoints
Mean IP Change from Baseline
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelSINGLE_GROUP
PurposeTREATMENT
Interventions
NameTypeDescription
XalatanDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Open-angle glaucoma * ocular hypertension Exclusion Criteria: \- VA worse than 0.60

Countries:United States
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Competitive Landscape -Open-Angle Glaucoma 9 trials