Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01765764 | Bimatoprost for the Treatment of Eyebrow Hypotrichosis | PHASE3 | COMPLETED | 357 | — | — | Mar 13, 2013 | Feb 11, 2014 | Apr 23, 2019 | 2 | United States, Canada |
The physician evaluated eyebrow fullness using the 4-point GEBA Scale where: 1=very sparse, 2=sparse, 3=full and 4=very full. The percentage of participants with at least a 1-grade increase from Baseline is reported.
| Arm | Type | Description |
|---|---|---|
| Bimatoprost Solution BID | EXPERIMENTAL | Bimatoprost solution twice a day (BID) in the morning and in the evening applied to each eyebrow for 7 months. |
| Bimatoprost Solution QD | EXPERIMENTAL | Vehicle to bimatoprost solution in the morning and bimatoprost solution once a day (QD) in the evening applied to each eyebrow for 7 months. |
| Vehicle to Bimatoprost Solution BID | PLACEBO_COMPARATOR | Vehicle to bimatoprost twice a day (BID) in the morning and the evening applied to each eyebrow for 7 months. |
| Name | Type | Description |
|---|---|---|
| bimatoprost solution | DRUG | Bimatoprost solution once a day or twice a day applied to each eyebrow for 7 months. |
| Vehicle to bimatoprost solution | DRUG | Vehicle to bimatoprost solution once or twice a day applied to each eyebrow for 7 months. |
Inclusion Criteria: -Adult participants with eyebrow hypotrichosis (inadequate eyebrow growth). Exclusion Criteria: * Patients with disease, infection, or abnormality of the eyebrow area * Patients with permanent eyebrow loss due to over-grooming