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Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) - December 5, 2025

Key Takeaway: Taysha Gene Therapies announced the grant of stock options to two new employees as part of its 2023 Inducement Plan, complying with Nasdaq Listing Rule 5635(c)(4). The options, totaling 212,000 shares, have an exercise price of $4.49 and will vest over four years. Taysha focuses on AAV-based gene therapies for severe CNS diseases, with its lead program targeting Rett syndrome.
Price reaction · baseline $5.05 (2025-12-05 close) · clean, no other TSHA news in the window
day 0 close
+7.9%
day 1
+5.1%
day 3 · peak
+14.1%

Market Sentiment Analysis

POSITIVE FACTORS

  • Taysha is advancing innovative gene therapies for severe CNS diseases.
  • The company has granted stock options to new employees, indicating growth.
  • Taysha's lead program targets Rett syndrome, addressing a significant unmet need.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+67%
120-day peak, hindsight
Typical move
1.7%
average across 4 past catalysts
Cash runway
~33 mo
Minimal dilution risk
Lead asset
TSHA-101
Phase 1 · Infantile GM2 Gangliosidosis (Disorder)

Full Press Release Details

DALLAS, Dec. 05, 2025 (GLOBE NEWSWIRE) -- Taysha Gene Therapies, Inc. (Nasdaq: TSHA) (Taysha or the Company), a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system (CNS), today announced that, on December 3, 2025, the Compensation Committee of Taysha's Board of Directors granted two new employees, in the aggregate, options to purchase 212,000 shares of the Company's common stock in connection with their employment. The stock options were granted under the Taysha Gene Therapies, Inc. 2023 Inducement Plan as an inducement material to the individuals entering employment with Taysha in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options have an exercise price of $4.49 which is equal to the closing price of Taysha's common stock on the date of grant. Each stock option has a 10-year term and will vest over four years, with 25% of the option vesting on the first anniversary of the vesting commencement date and the remaining 75% of the option vesting in equal monthly installments over the 36 months thereafter. Vesting of each stock option is subject to such employee's continued service to Taysha on each vesting date.
About Taysha Gene TherapiesTaysha Gene Therapies (Nasdaq: TSHA) is a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system. Its lead clinical program TSHA-102 is in development for Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. With a singular focus on developing transformative medicines, Taysha aims to address severe unmet medical needs and dramatically improve the lives of patients and their caregivers. The Company’s management team has proven experience in gene therapy development and commercialization. Taysha leverages this experience, its manufacturing process and a clinically and commercially proven AAV9 capsid in an effort to rapidly translate treatments from bench to bedside. For more information, please visithttp://www.tayshagtx.com.

Company Contact:Hayleigh CollinsSenior Director, Corporate Communications and Investor RelationsTaysha Gene Therapies, Inc.hcollins@tayshagtx.com

Media Contact:Carolyn HawleyInizio EvokeCarolyn.hawley@inizioevoke.com

Frequently Asked Questions

What is the purpose of the stock options granted?

The stock options were granted as an inducement for new employees under Nasdaq Listing Rule 5635.

How many shares were granted in total?

A total of 212,000 shares were granted to two new employees.

What is the exercise price of the stock options?

The exercise price of the stock options is $4.49.

What is Taysha's focus in biotechnology?

Taysha focuses on advancing AAV-based gene therapies for severe CNS diseases.

What condition does Taysha's lead program target?

Taysha's lead program targets Rett syndrome, a rare neurodevelopmental disorder.

Last updated: Dec 8, 2025