Full Press Release Details
Life Sciences Proposes Public Offering
Colo.-(BUSINESS WIRE)- February 19, 2026 - TriSalus Life Sciences, Inc. (Nasdaq: TLSI) ("TriSalus" or the
"Company"), an oncology focused medical technology company advancing novel drug delivery technologies alongside standard-of-care
therapies to improve outcomes for patients with solid tumors, today announced that it intends to offer to sell shares of its common stock
in an underwritten public offering. All of the shares to be sold in the offering are to be sold by TriSalus. In addition, TriSalus intends
to grant the underwriters a 30-day option to purchase up to 15% of the total number of shares of common stock sold in the offering, on
the same terms and conditions. The offering is subject to market and other conditions, and there can be no assurance as to whether or
when the offering may be completed, or as to the actual size or terms of the offering.
Street Capital Markets is acting as the sole book-runner for the proposed offering.
shares are being offered and sold by the Company pursuant to an effective shelf registration statement on Form S-3 (File No. 333-291509)
previously filed with the U.S. Securities and Exchange Commission (the "SEC") on November 13, 2025 and declared effective
by the SEC on December 4, 2025. The offering of such shares is being made only by means of a prospectus supplement that forms a part
of the registration statement. A preliminary prospectus supplement and accompanying base prospectus relating to the offering has been
or will be filed with the SEC and will be available for free on the SEC's website at http://www.sec.gov. When available, copies
of the preliminary prospectus supplement and the accompanying base prospectus relating to the offering may be obtained from Lake Street
Capital Markets, LLC at 121 South Eighth Street, Suite 1000, Minneapolis, MN 55402, or e-mail at prospectus@lakestreetcm.com. The final
terms of the proposed offering will be disclosed in a final prospectus supplement to be filed with the SEC.
press release shall not constitute an offer to sell or the solicitation of an offer to buy any of the securities described herein, nor
shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation, or sale would be unlawful
prior to registration or qualification under the securities laws of any such state or other jurisdiction.
TriSalus Life Sciences
Life Sciences is an oncology focused medical technology company seeking to transform outcomes for patients with solid tumors by
integrating its innovative delivery technology with standard-of-care therapies, and with its investigational immunotherapeutic, nelitolimod,
a class C Toll-like receptor 9 agonist, for a range of different therapeutic and technology applications. The Company's platform
includes devices that utilize a proprietary drug delivery technology and a clinical stage investigational immunotherapy. The Company's
three FDA-cleared devices use its proprietary Pressure-Enabled Drug Delivery (PEDD) approach to deliver a range of therapeutics:
the TriNav Infusion System and TriNav Infusion System LV for hepatic arterial infusion of liver tumors and the Pancreatic Retrograde
Venous Infusion System for pancreatic tumors. The PEDD technology is a novel delivery approach designed to address the anatomic limitations
of arterial infusion for the pancreas. The PEDD approach modulates pressure and flow in a manner that delivers more therapeutic to the
tumor and is designed to reduce undesired delivery to normal tissue, bringing the potential to improve patient outcomes. Nelitolimod,
the Company's investigational immunotherapeutic candidate, is designed to improve patient outcomes by treating the immunosuppressive
environment created by many tumors and which can make current immunotherapies ineffective in the liver and pancreas. Patient data generated
during Pressure-Enabled Regional Immuno-Oncology (PERIO) clinical trials support the hypothesis that nelitolimod delivered via
the PEDD technology may have favorable immune effects within the liver and systemically. The target for nelitolimod, TLR9, is expressed
across cancer types and the mechanical barriers addressed by the PEDD technology are commonly present as well. The Company is in the
final stages of data completion for a number of phase 1 clinical trials and will begin exploring partnership opportunities for development.
statements made in this press release are "forward-looking statements" within the meaning of Section 27A of the Securities
Act and Section 21E of the Securities Exchange Act of 1934, as amended, and are subject to the safe harbor created thereby under the
Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as "become,"
"may," "intend," "will," "expect," "anticipate," "believe" or
other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking
statements include, but are not limited to, statements regarding the expected trading commencement and closing date, TriSalus's
business, the commercial potential of its TriNav Infusion System, TriSalus's proprietary PEDD approach, the potential therapeutic
benefits and commercial potential of Nelitolimod, and TriSalus's technologies and other products in development. Such statements
are subject to certain risks and uncertainties, including, but not limited to, those inherent in the process of developing and commercializing
medical devices that are safe and effective for human use, discovering, developing and commercializing medicines that are safe and effective
to use as human therapeutics, and the endeavor of building a business around such medical devices and medicines. TriSalus's forward-looking
statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from
those expressed or implied by such forward-looking statements. Although TriSalus's forward-looking statements reflect the good
faith judgment of its management, these statements are based only on facts and factors currently known by TriSalus. As a result, you
are cautioned not to rely on these forward-looking statements. These and other risks concerning TriSalus's products and programs
are described in additional detail in TriSalus's preliminary prospectus supplement, annual report on Form 10-K, and most recent
Form 10-Q, which are on file with the Securities and Exchange Commission (the "SEC") and available at the SEC's website
(www.SEC.gov). These forward-looking statements are made as of the date of this press release, and TriSalus assumes no obligation
to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking
statements, except as required by law.
Feffer, Managing Director