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TriSalus Life Sciences, Inc.

TLSI
MedTech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$4.13
▼ -0.12 · -2.82%

Financials

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52W LOW $2.2052W HIGH $7.95
Volume
275.54 K
Value Traded
1.56 M
Short % Float
8.75%
-4.4%Week
-13.24%1 Month
-0.24%3 Month
-2.13%6 Month
-66.9%5 Year
-70.36%All Time

Cash Data

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  • Burn Trend
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Key Stats

Market Cap
254.30 M
EPS (TTM)
-0.46
P/E Ratio
-
Ent. Value
241.08 M
Total Shares
61.57 M
Float Shares
38.22 M
Insiders
37.93%
Institutions
35.38%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

TLSI Catalyst Timeline

Dated clinical, regulatory and corporate events for TriSalus Life Sciences, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for TriSalus Life Sciences, Inc.

113Total events
6Upcoming
19Tier-1 (high impact)
2020 to 2026Coverage

Upcoming catalysts 2

T2Product Launch
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T2Product Launch
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TriNav®Advance

Event history 50

▲FDA ApprovalFDA Decision
FDA 510(k) clearance for TriNav Advance PEDD device
liver embolizationsource ↗
●Quarterly UpdateCorporate
TriSalus reports second quarter 2026 financial results
▲Reimbursement / PricingPost-Market
CMS establishes G-code extending reimbursement for vascular embolization procedures using pressure-generating catheter
◆Oral PresentationPresentation
Virtual KOL event featuring new real-world evidence for Pressure-Enabled Drug Delivery in liver cancer
liver cancersource ↗
●R&D DayPresentation
Hosted virtual KOL event discussing new real-world evidence for PEDD in liver cancer
liver cancersource ↗
●PublicationPresentation
Submitted for publication data from PEDIR study evaluating tumor-to-normal ratio in HCC and hypovascular tumors
hepatocellular carcinoma and hypovascular tumorssource ↗
▲PublicationPresentation
Real-world PEDD study published in Journal of Comparative Effectiveness Research
liver tumorssource ↗
●Quarterly UpdateCorporate
2026 revenue guidance revised to $54M-$57M
▲Trial InitiationTrial
Launch of PREDICTT clinical trial evaluating Pressure-Enabled Drug Delivery in liver tumors
liver tumorssource ↗
◆Oral PresentationPresentation
Novel Approaches to Uterine Artery Embolization: A Clinical Assessment of Safety and Efficacy Using a Pressure Enabled Drug Delivery Device
Uterine fibroidssource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How TLSI actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2023-06-30SD-101 Phase 1 data readout Phase 1
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D23 / 100
Pipeline Score
$35M
Pipeline Value
Not rated
Valuation Signal
1
Drugs Scored
0.1x
rNPV / MCap
Top 88%
Micro Cap
(rank 579 of 658)
Percentile Rank
TriSalus Life Sciences, Inc. faces pipeline headwinds (23/100), with $368M risk-adjusted pipeline value, led by SD-101 in Prostatic Neoplasms (Phase 2).
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
SD-101 Small moleculeCompletedNCT03007732Prostatic NeoplasmsPhase 2 COMPLETED 23Mar 31, 2025
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Clinical Trial Results

Readouts, endpoints and source filings for every TLSI program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
SD-101 uveal melanoma liver metastasesPhase 12023-06-12treatment related serious adverse event rate: 5%; patients enrolled: 39; treatment naive patients: 5; patients failed prior therapy: 81%; stable disease patients: 15; partial response patients: 1; ct DNA decrease patients: 8; evaluable patients: 13Read MoreTriSalus Life Sciences Presents Additional Data for SD-101 Delivered by the Proprietary PEDD Method with the TriNav Device for Uveal Melanoma Liver Metastases at the ASCO 2023 Annual Meeting New datRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Stevens JenniferOfficer (Chief Regulatory Officer)Sell -316 123,794 held$4.39 10/05/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in TLSI for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

TLSI Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

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LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

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Competitive positioning

How TLSI ranks across every disease it competes in

Competitive Position is a premium feature
See how TLSI ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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TLSI News

TLSI
Sep 22, 2026
TLSIFDA Updates

TriSalus Life Sciences Receives FDA Clearance for TriNav® Advance, Strengthening Comprehensive Pressure-Enabled Drug Delivery™ (PEDD™) Portfolio for Liver Embolization

TriSalus Life Sciences has received FDA 510(k) clearance for TriNav® Advance, enhancing its Pressure-Enabled Drug Delivery™ (PEDD™) portfolio. This new device aims to improve treatment delivery for patients with solid tumors, integrating advanced technology with existing therapies. The clearance marks a significant step in TriSalus's commitment to oncology innovation.

Read more →
TLSI
Aug 31, 2026
TLSIConferences/Events

TriSalus Life Sciences to Participate in the H.C. Wainwright & Company 28th Annual Global Investment Conference

TriSalus Life Sciences will participate in the H.C. Wainwright & Company 28th Annual Global Investment Conference. This event is significant for the company as it allows them to engage with investors and showcase their developments. Participation in such conferences can enhance their visibility in the biopharma sector.

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TLSI
Aug 6, 2026
TLSIGeneral
▲ +15.2%on this news

TriSalus Life Sciences Reports Second Quarter 2026 Results

TriSalus Life Sciences reported its financial results for Q2 2026, highlighting significant year-over-year and sequential growth. The company is focused on integrating novel delivery technologies with standard therapies to improve treatment for solid tumors. This operational update reflects the company's commitment to advancing oncology care.

Read more →
TLSI
Jul 29, 2026
TLSIConferences/Events

TriSalus Life Sciences to Participate in the Canaccord Genuity 46th Annual Growth Conference

TriSalus Life Sciences will participate in the Canaccord Genuity 46th Annual Growth Conference, featuring CEO Mary Szela and CFO David Patience. The event will include one-on-one meetings, highlighting the company's commitment to oncology and investor engagement. This participation reflects the company's ongoing efforts to enhance its visibility in the biopharma sector.

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TLSI
Jul 16, 2026
TLSIConferences/Events

TriSalus Life Sciences to Host Second Quarter 2026 Financial Results Conference Call

TriSalus Life Sciences, an oncology-focused company, has announced a conference call scheduled for August 6, 2026. The call will discuss the financial results for the quarter ending June 30, 2026. This event highlights the company's commitment to transparency and investor engagement.

Read more →
TLSI
Jun 10, 2026
TLSIConferences/Events
▲ +6.3%on this news· ran to +26% by day 3

TriSalus Life Sciences to Host Virtual KOL Event on June 24 Featuring New Real-World Evidence for Pressure-Enabled Drug Delivery™ in Liver Cancer

TriSalus Life Sciences is set to host a virtual Key Opinion Leader (KOL) event on June 24. The event will showcase new real-world evidence regarding their Pressure-Enabled Drug Delivery™ technology specifically for liver cancer treatment. This initiative highlights the company's commitment to advancing therapeutic options in oncology.

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TLSI
May 12, 2026
TLSIGeneral

Real-World PEDD Study Published in the Journal of Comparative Effectiveness Research Shows Improved Clinical Outcomes and Meaningful Charge Avoidance

The article discusses a real-world study published in the Journal of Comparative Effectiveness Research that highlights improved clinical outcomes and charge avoidance related to PEDD. However, specific details about the study's findings or implications are not provided in the text.

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TLSI
May 12, 2026
TLSIGeneral

TriSalus Life Sciences Reports First Quarter 2026 Results Demonstrating Commercial and Clinical Progress for Facilitating Long-Term Growth

TriSalus Life Sciences has reported its first quarter 2026 results, highlighting both commercial and clinical advancements aimed at fostering long-term growth. The report indicates the company's ongoing efforts to enhance its market position and clinical outcomes. However, specific details regarding financial performance or clinical data were not disclosed in the article.

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TLSI
May 4, 2026
TLSIPhases

TriSalus Life Sciences Announces Launch of PREDICTT Clinical Trial Evaluating Pressure-Enabled Drug Delivery in Liver Tumors

TriSalus Life Sciences has announced the launch of the PREDICTT clinical trial, which aims to evaluate a novel pressure-enabled drug delivery system for treating liver tumors. This innovative approach could enhance the effectiveness of therapies for patients with this challenging condition. The trial represents a significant step forward in cancer treatment methodologies.

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TLSI
Apr 28, 2026
TLSIConferences/Events

TriSalus Life Sciences to Host First Quarter 2026 Financial Results Conference Call

TriSalus Life Sciences will host a conference call on May 12, 2026, to discuss its financial results for Q1 2026. The company focuses on integrating novel delivery technology with standard therapies for solid tumors. Their investigational immunotherapeutic, nelitolimod, aims to enhance treatment outcomes by addressing immunosuppressive environments. A press release will precede the call.

Read more →
TLSI
Apr 9, 2026
TLSIConferences/Events

TriSalus Life Sciences to Present New Data at the 2026 Society of Interventional Radiology Annual Scientific Meeting

TriSalus Life Sciences will present new data at the Society of Interventional Radiology Annual Scientific Meeting in April 2026. The company will showcase its Pressure Enabled Drug Delivery platform, which aims to enhance therapeutic delivery for solid tumors. Presentations will include findings on hepatic tumor penetration and uterine artery embolization. The data supports the potential of PEDD in improving treatment outcomes.

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TLSI
Apr 7, 2026
TLSIGeneral

TriSalus Life Sciences Appoints Richard Marshall, M.D., as Chief Medical Officer

TriSalus Life Sciences has announced the appointment of Richard Marshall, M.D., as their new Chief Medical Officer. This strategic move is expected to enhance the company's leadership team. Further details regarding his previous experience and future plans at TriSalus were not disclosed in the announcement.

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TLSI
Feb 26, 2026
TLSIConferences/Events

TriSalus Life Sciences to Host Fourth Quarter 2025 Financial Results Conference Call

TriSalus Life Sciences will host a conference call on March 5, 2026, to discuss its financial results for Q4 2025. The call will provide insights into the company's performance and future plans, including its innovative drug delivery technologies and investigational immunotherapeutic, nelitolimod. A press release will precede the call, and a replay will be available afterward.

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TLSI
Feb 20, 2026
TLSIGeneral
▲ +18.2%on this news

TriSalus Life Sciences Announces Pricing of $40.0 Million Public Offering

TriSalus Life Sciences has announced the pricing of its public offering, selling 9,756,100 shares at $4.10 each, aiming to raise approximately $40 million. The offering is expected to close around February 23, 2026, pending customary closing conditions. Lake Street Capital Markets is the sole book-runner for this offering.

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TLSI
Feb 19, 2026
TLSIGeneral

TriSalus Life Sciences Proposes Public Offering

TriSalus Life Sciences, an oncology-focused medical technology company, announced its intent to conduct an underwritten public offering of its common stock. The offering entails all shares being sold by the company, with underwriters receiving an option for additional shares. The final terms of the offering will be disclosed in a prospectus supplement to be filed with the SEC. Various aspects of the public offering and TriSalus's future potential treatments are discussed in light of market conditions and regulatory compliance.

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TLSI
Feb 10, 2026
TLSIGeneral

TriSalus Life Sciences Appoints Veteran Healthcare Investor Michael Stansky to its Board of Directors

TriSalus Life Sciences has appointed Michael Stansky to its Board of Directors, effective February 4, 2026, following the resignation of Dr. Arjun Desai. Stansky brings 40 years of experience in investment management and healthcare, which the company believes will support its strategic growth objectives. The board expressed gratitude for Desai's contributions during his tenure.

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TLSI
Jul 24, 2025
TLSIGeneral

TriSalus Life Sciences Announces Expiration and Results of Exchange Offer and Consent Solicitation Relating to Series A Convertible Preferred Stock

TriSalus Life Sciences has successfully completed its exchange offer for Series A Convertible Preferred Stock, with nearly 99% of shares tendered in the process. The exchange allows holders to convert their preferred shares into common stock at a ratio of 3.3 shares. The SEC's effective declaration of the registration statement facilitates this transition, which is expected to be finalized by August 1, 2025. The initiative highlights the company's ongoing focus on oncology advancements and improving patient outcomes.

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TLSI
May 30, 2025
TLSIGeneral
▼ -8.8%on this news

TriSalus Life Sciences Announces Chief Financial Officer Transition with Appointment of David B. Patience

TriSalus Life Sciences has announced the appointment of David B. Patience as Chief Financial Officer, effective July 1, 2025. He succeeds James E. Young, who stepped down for personal reasons. David Patience brings extensive experience from his previous role as CFO at Accelerate Diagnostics and has a strong background in strategic product planning and market analysis. The transition aims to maintain stability while leveraging Patience's financial leadership in the company's growth efforts.

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TLSI
Apr 30, 2025
TLSIGeneral
▼ -10.3%on this news

TriSalus Life Sciences Announces $22.0 Million Preliminary Q1 2025 Unaudited Financial Results

TriSalus Life Sciences has announced a private placement of $22 million, aimed at accelerating current and future applications of its cancer treatment technologies. Preliminary financial results for Q1 2025 indicate a revenue of approximately $9.2 million, reflecting a 42% growth compared to Q1 2024. The company plans to simplify its capital structure through an exchange offer for its Series A Convertible Preferred Stock, which is expected to enhance operational efficiency. The funds raised will be utilized for working capital and corporate purposes, as the company continues to advance its innovative therapies for solid tumors.

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About TriSalus Life Sciences, Inc.

Westminster, CO 102 employees trisaluslifesci.com
Headquarters6272 WEST 91ST AVENUE, WESTMINSTER, CO, 80031
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