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Sionna Therapeutics Announces Closing of $219.2 million Upsized Initial Public Offering, Including Full Exercise of Underwriters’ Option to Purchase Additional Shares

Key Takeaway: Sionna Therapeutics, a biopharmaceutical firm focused on cystic fibrosis treatment, has completed its upsized initial public offering, raising $219.2 million. The offering included 12,176,467 shares sold at a price of $18.00 each, with all shares sold by the company. Trading of its stock began on February 7, 2025, under the ticker SION on the Nasdaq. The funds will support the development of novel therapies aimed at normalizing cystic fibrosis transmembrane conductance regulator (CFTR) protein function.
Price reaction · baseline $25 (2025-02-07 close) · clean, no other SION news in the window
day 0 close
-11%
day 1
-18.4%
day 3 · peak
-18.9%

Market Sentiment Analysis

POSITIVE FACTORS

  • Successfully closed upsized IPO raising approximately $219.2 million.
  • Trading commenced on Nasdaq Global Market under ticker SION.
  • Sionna Therapeutics aims to revolutionize cystic fibrosis treatment with innovative medicines.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~37 mo
Minimal dilution risk
Lead asset
SION-719
Phase 2 · Cystic Fibrosis (CF)

Full Press Release Details

BOSTON, Feb. 10, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced the closing of its upsized initial public offering of 12,176,467 shares of its common stock at a public offering price of $18.00 per share, which includes 1,588,234 shares issued upon the full exercise by the underwriters of their option to purchase additional shares of common stock in the offering. All of the shares of common stock were sold by Sionna.
The gross proceeds to Sionna from the initial public offering were, including full exercise of the underwriters’ option to purchase additional shares, approximately $219.2 million, before deducting underwriting discounts and commissions and offering expenses. The shares commenced trading on the Nasdaq Global Market on February 7, 2025 under the ticker symbol “SION.”
Goldman Sachs & Co. LLC, TD Cowen, Stifel, and Guggenheim Securities acted as joint book-running managers for the offering.
A registration statement relating to the shares sold in the initial public offering has been filed with the Securities and Exchange Commission and was declared effective by on February 6, 2025. This offering was made only by means of a prospectus. A copy of the final prospectus may be obtained from Goldman Sachs & Co. LLC, Attention: Prospectus Department, 200 West Street, New York, NY 10282, via telephone: (866) 471-2526, via fax: 212 902-9316, or via email: prospectus-ny@ny.email.gs.com; TD Securities (USA) LLC, 1 Vanderbilt Avenue, New York, NY 10017, by telephone at (855) 495-9846, or by email at TD.ECM_Prospectus@tdsecurities.com; Stifel, Nicolaus & Company, Incorporated, Attention: Syndicate, One Montgomery Street, Suite 3700, San Francisco, CA 94104, by telephone at (415) 364-2720, or by email at syndprospectus@stifel.com; and Guggenheim Securities, LLC, Attention: Equity Syndicate Department, 330 Madison Avenue, 8th Floor, New York, NY 10017, or by telephone at (212) 518-9544 or by email at GSEquityProspectusDelivery@guggenheimpartners.com.
This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
About Sionna Therapeutics
Sionna Therapeutics is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for CF by developing novel medicines that normalize the function of the CFTR protein. Sionna’s goal is to deliver differentiated medicines for people living with CF that can restore their CFTR function to as close to normal as possible by directly stabilizing CFTR’s nucleotide-binding domain 1 (NBD1), which the company believes is central to potentially unlocking dramatic improvements in clinical outcomes and quality of life for people with CF. Leveraging more than a decade of the co-founders’ research on NBD1, the company is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in NBD1. Sionna is also developing a portfolio of complementary CFTR modulators that are designed to work synergistically with its NBD1 stabilizers to improve CFTR function.

Frequently Asked Questions

What did Sionna Therapeutics announce on February 10, 2025?

Sionna Therapeutics announced the closing of its upsized initial public offering.

How many shares were offered in Sionna's IPO?

Sionna's IPO included 12,176,467 shares of common stock.

What are Sionna's goals for cystic fibrosis treatment?

Sionna aims to develop medicines that normalize CFTR protein function.

What is the ticker symbol for Sionna's shares?

Sionna's shares trade under the ticker symbol 'SION'.

How much did Sionna raise from the IPO?

Sionna raised approximately $219.2 million from the IPO.

Last updated: Feb 10, 2025