Sotera Health Confirms Preliminary 2022 Full-Year Guidance in Conjunction with Incremental Debt Financing Cleveland, Ohio

Sotera Health Confirms Preliminary 2022 Full-Year Guidance

in Conjunction with Incremental Debt Financing

Cleveland, Ohio February 13, 2023 Sotera Health Company ( Sotera Health or the Company ) (NASDAQ: SHC),

a leading global provider of mission-critical end-to-end sterilization solutions, lab testing and advisory services for the healthcare industry, today announced its

intention to enter into a new senior secured Term Loan B facility in an aggregate principal amount of $425 million, which is expected to fund and close during the first quarter. The Company plans to use proceeds of this debt financing, along

with cash on hand, to: a) fund a previously announced planned $408 million ethylene oxide litigation settlement in Cook County, IL, b) pay down existing borrowings under the Company s revolving credit facility, and c) further enhance

Preliminary Financial Results for the Year Ended December 31, 2022

Our financial statements for the year ended December 31, 2022 are not yet complete. Accordingly and related to this incremental debt financing, we are

presenting preliminary estimates of certain financial information that we expect to report on February 28, 2023 for the year ended December 31, 2022. The following information is based on our internal management accounts and reporting as

of and for the year ended December 31, 2022, as compared to our audited results for the year ended December 31, 2021. Given the timing of these estimates, we have not completed our customary financial closing and review procedures but are

making these estimates available to facilitate the incremental debt financing.

The Company is reaffirming its expectation that 2022 full-year net

revenues will be within the previously announced guidance range of $995 million to $1.005 billion. The Company also is announcing that the 2022 full-year net loss is expected to be in a range of $226 million to $236 million,

which includes a $408 million legal reserve recorded in Q4 2022 related to the binding term sheets to settle 870+ ethylene oxide claims in Cook County, IL, subject to the satisfaction or waiver of the various conditions set forth in the term

sheets. Full-year Adjusted EBITDA will be in the previously announced guidance range of $500 million to $510 million. Adjusted EBITDA is a non-GAAP financial measure; a reconciliation of Adjusted

EBITDA to its most closely comparable GAAP figure is included at the end of this release.

The preliminary financial information included in this release

has been prepared by, and is the responsibility of, the Company s management. The preliminary estimated results of operations are subject to revision as we finalize our financial statements and disclosure for the year ended December 31,

2022, and such revisions may be significant. Estimates of financial results are inherently uncertain and we undertake no obligation to update this information before announcement of final results for 2022.

9100 South Hills Boulevard, Suite 300, Broadview Heights, OH 44147

440-262-1410 | soterahealth.com

In connection with our annual closing and review process for the fiscal year 2022, we may identify items that

would require us to make adjustments to the preliminary estimated results of operations set forth in this release. Accordingly, the final results and other disclosures for the year ended December 31, 2022 may differ materially from the

preliminary estimates being announced today. This preliminary estimated financial data should not be viewed as a substitute for financial statements prepared in accordance with U.S. GAAP. The Company expects to file its Annual Report on Form 10-K for the year ended December 31, 2022 on February 28, 2023, its previously announced reporting date. Ernst & Young LLP, our independent registered public accounting firm, has not audited,

reviewed, compiled, or applied agreed-upon procedures with respect to the preliminary estimated financial data for the year ended December 31, 2022 that we are presenting here. Accordingly, Ernst & Young LLP does not express an opinion

or any other form of assurance with respect thereto.

Non-GAAP Financial Measures

To supplement our consolidated financial statements presented in accordance with GAAP, we consider Adjusted EBITDA, a financial measure that is not based on

any standardized methodology prescribed by GAAP.

We define Adjusted EBITDA as net income (loss) before interest expense and the mark-to-market impact of derivatives not accounted for as hedges, income taxes, depreciation (including depreciation of Co-60 used in

our operations), amortization of intangible assets and certain other adjustments that we do not consider in our evaluation of our ongoing operating performance from period to period.

In evaluating Adjusted EBITDA, you should be aware that, in the future, we will incur expenses similar to the adjustments in this presentation. Our

presentation of Adjusted EBITDA should not be construed as suggesting that our future results will be unaffected by these expenses or any unusual or non-recurring items. When evaluating our performance, you

should consider Adjusted EBITDA alongside other financial performance measures, including our net income and other GAAP measures.

About Sotera Health:

Sotera Health Company is a leading global provider of mission-critical

end-to-end sterilization solutions and lab testing and advisory services for the healthcare industry. Sotera Health goes to market through three businesses

Sterigenics , Nordion and Nelson Labs . Sotera Health is committed to its

mission, Safeguarding Global Health .

Updates can be found from time to time on recent

developments in matters relevant to investors on the Investor Relations section of the Company s website at Investor Relations | Sotera Health. For developments related to Ethylene Oxide, updates can be found at Ethylene Oxide |

9100 South Hills Boulevard, Suite 300,

Broadview Heights, OH 44147

440-262-1410 | soterahealth.com

Forward-looking Statements

This release contains forward-looking statements that reflect management s expectations about future events and the Company s operating plans and

speak only as of the date hereof. You can identify these forward-looking statements by the use of forward-looking words such as will, may, plan, estimate, expect, could, or the

negative version of those words or other comparable words, including statements regarding the potential terms, timing and completion of the Term Loan B facility and the use of related proceeds. In addition, any statements that refer to expectations,

projections or other characterizations of future events or circumstances, are forward-looking statements. Any forward-looking statements contained in this release are based upon our historical performance and on our current plans, estimates and

expectations of the Company s future performance and the future performance of the markets in which the Company operates in light of information currently available to us. The inclusion of this forward-looking information should not be regarded

as a representation by us that the future plans, estimates or expectations contemplated by us will be achieved, and there can be no assurance that the proposed Term Loan B facility will be consummate on the terms described herein or at all. These

forward-looking statements are subject to various risks, uncertainties and assumptions relating to our operations, financial results, financial condition, business, prospects, growth strategy and liquidity. These risks and uncertainties include,

without limitation, any disruption in the availability or supply of, or increases in the price of, ethylene oxide ( EO ) or cobalt-60 ( Co-60 ),

including geopolitical risks related to the supply of Co-60 from Russia; foreign currency exchange rates and changes in those rates; changes in industry trends, environmental, health and safety regulations or

preferences; satisfaction of conditions to completing the settlement, including the participation by substantially all Illinois plaintiffs in the settlement; the impact of current and future legal proceedings and liability claims, including

litigation related to purported exposure to emissions of EO from our facilities in Illinois, Georgia and New Mexico and the possibility that other claims will be made in the future relating to these or other facilities; adverse judgments against two

of our subsidiaries in the EO tort litigation, which if the settlement is not successful may require an appellate bond or alternative form of security to appeal, and plaintiff efforts to enforce judgments against us, any of which may have an adverse

impact on our liquidity in the near and long terms; whether we will be able to close the new Term Loan B facility on expected terms or at all; uncertainty in the capital markets and other risks related to our ability to raise additional debt

financing on reasonable terms or at all, including availability of capital and the impact of future litigation developments on our ability to access capital markets; our ability to increase capacity at existing facilities, renew leases for our

leased facilities and build new facilities in a timely and cost-effective manner; competition for qualified employees in the industries in which we operate; the risks of doing business internationally; and any inability to pursue strategic

transactions or find suitable acquisition targets. For additional discussion of these risks and uncertainties, please refer to those described in the Company s Annual Report on Form 10-K for the year

ended December 31, 2021, and the Company s other filings with the SEC, including its Quarterly Reports on Form 10-Q, including under the headings Risk Factors and Cautionary Note

Regarding Forward-Looking Statements as well as the Current Report on Form 8-K filed by the Company on January 9, 2023 with the SEC disclosing the terms of the settlement and related risks.

9100 South Hills Boulevard, Suite 300,

Broadview Heights, OH 44147

440-262-1410 | soterahealth.com

INVESTOR RELATIONS CONTACTS:

Chief Marketing Officer, Sotera Health

Source: Sotera Health Company

9100 South Hills Boulevard, Suite 300,

Broadview Heights, OH 44147

440-262-1410 | soterahealth.com

Sotera Health Company

Non-GAAP Financial Measures

9100 South Hills Boulevard, Suite 300,

Broadview Heights, OH 44147

440-262-1410 | soterahealth.com

9100 South Hills Boulevard, Suite 300,

Broadview Heights, OH 44147

440-262-1410 | soterahealth.com