Recent Updates
Recently added Catalysts
MGNX Negative Sentiment Score: 25/100

MacroGenics (MGNX) Investigating Three of Five Patient Deaths in TAMARACK Study of Vobra Duo, Stock Flat After May 10, 2024 Crash – Hagens Berman

Key Takeaway: MacroGenics, Inc. (MGNX) is facing scrutiny over its TAMARACK study of the antibody-drug conjugate MGC018 following the investigation into five patient deaths. The interim safety data released in April indicated improved tolerability, leading to a significant rise in share prices. However, subsequent disclosures of the patient fatalities resulted in a dramatic 77% drop in stock value and analyst downgrades over safety concerns. The company is currently investigating the deaths of three patients and has yet to update investors on its findings.

Market Sentiment Analysis

POSITIVE FACTORS

  • MacroGenics had previously observed increased safety and tolerability in an interim readout.
  • The TAMARACK study initially led to a significant share price increase for MacroGenics.

CONCERNS & RISKS

  • Five patient deaths in the TAMARACK study have raised serious safety concerns.
  • The company's share price fell drastically by about 77% following the safety disclosure.
  • Analysts, including Stifel, have downgraded MacroGenics due to discrepancies in safety data.

Full Press Release Details

SAN FRANCISCO, July 10, 2024 (GLOBE NEWSWIRE) -- Hagens Berman urges MacroGenics, Inc. (NASDAQ: MGNX) investors who suffered substantial losses to submit your losses now.
Contact the Firm Now: MGNX@hbsslaw.com
Investigation into MacroGenics, Inc. (MGNX):
The current investigation scrutinizes the accuracy of MacroGenics’ statements regarding data from its Phase 2 TAMARACK study of the antibody-drug conjugate MGC018, known as “vobra duo,” in patients with metastatic castration-resistant prostate cancer (mCRPC).
On Apr. 3, 2024, MacroGenics released interim safety data from the TAMARACK study, as detailed in an abstract submitted to the American Society of Clinical Oncology on Feb. 6, 2024. The company stated, “Preliminary safety data from TAMARACK suggest that reducing the dose and frequency of vobra duo improves its safety and tolerability in men with mCRPC.” This announcement led to a significant increase in MacroGenics’ share price, which rose by $4.11, or approximately 30%, on Apr. 4, 2024.
However, the positive sentiment was short-lived. On May 10, 2024, MacroGenics disclosed that five patients in the study had died. This revelation caused the company’s share price to plummet by $11.36, or about 77%, on the same day, prompting numerous analyst downgrades.
Additionally, Seeking Alpha reported that “Stifel was quick to downgrade MacroGenics (MGNX) after the TAMARACK readout, which, according to the firm, raised concerns over the drug’s safety and tolerability and appeared vastly different from previously disclosed abstract results.”
While the company said it was investigating the deaths of three patients in the study, it has not yet provided an update to investors.
“We’re investigating whether MacroGenics may have misled investors about its Phase 2 TAMARACK interim safety data,” said Reed Kathrein, the Hagens Berman partner leading the investigation.
If you invested in MacroGenics and have substantial losses submit your losses now »
If you’d like more information about the MacroGenics investigation, read more »
Hagens Berman is a global plaintiffs’ rights complex litigation firm focusing on corporate accountability. The firm is home to a robust practice and represents investors as well as whistleblowers, workers, consumers and others in cases achieving real results for those harmed by corporate negligence and other wrongdoings. Hagens Berman’s team has secured more than $2.9 billion in this area of law. More about the firm and its successes can be found at hbsslaw.com. Follow the firm for updates and news at @ClassActionLaw.
Reed Kathrein, 844-916-0895

Tags

Frequently Asked Questions

What is the investigation into MacroGenics about?

The investigation focuses on the accuracy of MacroGenics’ statements regarding the Phase 2 TAMARACK study data for MGC018 in patients with mCRPC.

What happened to MacroGenics shares on May 10, 2024?

Shares of MacroGenics plummeted by $11.36, roughly 77%, following the disclosure of five patient deaths in the TAMARACK study.

Why did MacroGenics receive analyst downgrades?

Analysts, including Stifel, downgraded MacroGenics due to concerns about the safety and tolerability of vobra duo after the TAMARACK study results.

How can affected MacroGenics investors act?

Investors who faced significant losses in MacroGenics are urged to submit their losses now for potential legal action.

Last updated: Jul 10, 2024