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Veradermics’ Oral VDPHL01 Delivers Positive Study ‘207’ Phase 2 Clinical Trial Results in Female Pattern Hair Loss Ahead of Upcoming Phase 2/3 Study ‘306’ Readout

Key Takeaway: Veradermics, Incorporated announced positive topline results from its Phase 2 clinical trial of VDPHL01, an oral minoxidil formulation for female pattern hair loss. The trial demonstrated effectiveness in females with mild-to-moderate hair loss. This development positions VDPHL01 as a potential first FDA-approved oral treatment for this condition, with further studies planned.
Price reaction · baseline $110.17 (2026-07-14 close) · hit pre-market · 1 other MANE headline(s) in the window, move may be shared
day 0 close · peak
+12.3%
day 1
-3.9%
day 3
-3.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • Positive topline results from the Phase 2 trial.
  • Potential for VDPHL01 to be the first FDA-approved oral treatment for hair loss.
  • Focus on innovative therapeutics for pattern hair loss.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~53 mo
Minimal dilution risk
Lead asset
VDPHL01
Phase 3 · Androgenetic Alopecia

Full Press Release Details

Conference call will take place on Wednesday, July 15, 2026 at 8:00 am ET
NEW HAVEN, Conn.--(BUSINESS WIRE)--Veradermics, Incorporated (NYSE: MANE), a dermatologist-founded, late-stage biopharmaceutical company focused on developing innovative therapeutics for pattern hair loss, today announced it will host an investor call and live webcast on Wednesday, July 15, 2026 at 8:00 am ET to review results from female treatment arms of the Phase 2 open-label Study ‘207’ evaluating VDPHL01, a proprietary extended-release oral minoxidil tablet, in males and females with mild-to-moderate pattern hair loss.
Webcast Details:Time:Wednesday, July 15, 2026 at 8:00 a.m. ET.Joining:The event and the accompanying slides will be available on theEventspage in the Investors section of the Company’swebsite. A replay will be available following the call.
About VDPHL01VDPHL01 (extended-release minoxidil tablet) is a proprietary investigational, oral non-hormonal drug in Phase 3 development for pattern hair loss in both women and men. VDPHL01 leverages extended-release technology to deliver a minoxidil product with the potential for improved efficacy and safety. The proprietary extended-release formulation utilizes a gel matrix designed to deliver long-lasting, steady release of minoxidil for sustained absorption. VDPHL01 has been shown to avoid the high peak concentrations of immediate-release oral minoxidil, while extending time above the minimum hair growth threshold to increase time for hair to grow. If approved, VDPHL01 would be the only FDA-approved oral non-hormonal treatment for pattern hair loss in both male and female patients. VDPHL01 is protected by a broad library of patents and patent applications related to the key innovations of VDPHL01. The earliest expiring patent term is 2043.
About Pattern Hair LossPattern hair loss, also known as androgenetic alopecia, affects an estimated 80 million people in the United States (30 million women and 50 million men). Pattern hair loss can have a significant impact on quality of life, affecting an individual’s mental health and relationships. People with pattern hair loss often experience depression, low self-esteem and social withdrawal. There have been no new FDA-approved prescription medicines for pattern hair loss in nearly 30 years. In addition to prescription medicines, current treatments include over-the-counter “nutraceuticals” that produce inconsistent results and contribute to high dissatisfaction among patients and healthcare providers. The prevalence of pattern hair loss and the market demand for new treatments contribute to making it the largest aesthetics market worldwide, projected to reach approximately $30 billion by 2028.
About Veradermics, Inc.Veradermics is a dermatologist-founded, late clinical-stage biopharmaceutical company focused on developing innovative therapeutics for pattern hair loss. Veradermics aims to develop a focused portfolio of aesthetic dermatology product candidates targeting high-prevalence dermatologic conditions, with potential selective development of medical dermatology product candidates. Its lead program, VDPHL01, is being developed as an oral, non-hormonal treatment for men and women with pattern hair loss, to reduce the barriers to wide adoption of chronic hair loss therapy and potentially transform pattern hair loss treatment. VDPHL01 is an oral, extended-release proprietary formulation of minoxidil, a proven hair growth agent, designed to maximize minoxidil’s impact on hair restoration while minimizing the risk of cardiac activity. For additional information, visitwww.veradermics.comand follow us on LinkedIn and Instagram.

Frequently Asked Questions

What are the results of the Phase 2 trial for VDPHL01?

The Phase 2 trial showed positive topline results for VDPHL01 in treating female pattern hair loss.

What is VDPHL01?

VDPHL01 is a proprietary extended-release oral minoxidil formulation developed for pattern hair loss.

What is the significance of these results?

These results indicate VDPHL01's potential to be the first FDA-approved oral treatment for female pattern hair loss.

What is the next step for Veradermics?

Veradermics plans to conduct further studies, including a Phase 2/3 study for VDPHL01.

Last updated: Jul 15, 2026