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VDPHL01

Phase 3

Androgenetic Alopecia | Small molecule | Dermatology |Veradermics, Incorporated|Last Updated: Aug 17, 2026

Target and mechanism

Molecular targetminoxidil
Target classHair Growth Agent
ModalitySmall molecule

Also known as VDPHL01 QD

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials3
Total Enrollment1,030

FDA Designations

No designations recorded

Clinical trial landscape

VDPHL01 · 4 trials · 6 indications

Phase 3 2Phase 2 2
NCT07146022Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)Androgenetic Alopecia (AGA)
ACTIVE NOT_RECRUITING552 Analytics
NCT06972264Safety and Efficacy of VDPHL01 in Males With AGAAndrogenetic Alopecia
ACTIVE NOT_RECRUITING480 Analytics
PHASE3ACTIVE NOT_RECRUITING
Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)
Androgenetic Alopecia (AGA)Unlock trial analytics
PHASE3ACTIVE NOT_RECRUITING
Safety and Efficacy of VDPHL01 in Males With AGA
Androgenetic AlopeciaUnlock trial analytics

Study Endpoints

Primary Endpoints

Changes in non-vellus Target Area Hair Counts (TAHC)
Month 6

Changes from baseline in non-vellus TAHC using digital image analysis at Month 6.

Subjects Evaluation of Treatment Benefit
Month 6

Subjects will rate their treatment benefit by responding to a hair assessment scale. The proportion of subjects by each response category will be reported at Month 6.

Changes in non-vellus Total Area Hair Count (TAHC)
Month 12

Change from baseline in non-vellus TAHC using digital image analysis at Month 12.

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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
VDPHL01 BIDEXPERIMENTALVDPHL01 will be taken orally twice a day (BID), once in the AM and once in the PM for the first 6 months of the study. After month 6, subject will continue VDPHL01 BID for an additional 6 months.
VDPHL01 QD and Placebo QDEXPERIMENTALPlacebo will be taken orally once a day (QD) in the AM or PM. VDPHL01 will be taken orally once a day (QD) in the AM or PM for the first 6 months of the study. After month 6, subject will continue this same dose regimen for an additional 6 months.
Placebo BID with treatment extension to VDPHL01 BIDPLACEBO_COMPARATORPlacebo will be taken orally twice a day (BID), once in the AM and once in the PM for the first 6 months of the study. After month 6, subject will switch to VDPHL01 BID group, and take VDPHL01 orally twice a day (BID), once in the AM and once in the PM for an additional 6 months.
Placebo BID with treatment extension to VDPHL01 QD and Placebo QDPLACEBO_COMPARATORPlacebo will be taken orally twice a day (BID), once in the AM and once in the PM for the first 6 months of the study. After month 6, subject will switch to VDPHL01 QD and Placebo QD group, and take placebo orally once a day in the AM or PM; VDPHL01 will be taken orally once a day in the AM or PM for an additional 6 months.
VDHPL01 BIDEXPERIMENTALVDPHL01 will be taken orally twice a day, once in the AM and once in the PM.
VDPHL01 TabletEXPERIMENTAL -

Interventions

NameTypeDescription
VDPHL01 QDDRUGVDPHL01 Extended Release (ER) Tablet
PlaceboDRUGPlacebo tablet
VDPHL01 BIDDRUGVDPHL01 Extended Release (ER) Tablet
VDPHL01DRUGVDPHL01 Extended Release (ER) Tablet
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Eligibility Criteria

Age Range18 Years to 65 Years
SexFEMALE
Healthy VolunteersNo
Study Sites71

Inclusion Criteria: * Subject is a female aged 18-65 years old; * Subject has a clinical diagnosis of mild to moderate AGA; * Subject is in good general health and has adequate renal and hepatic function; * Subject is willing to maintain at least 1/4 inch length hair during the study with the same ...

Countries:United States
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Recent Changes (Last 90 Days)

MEDIUMAug 17, 2026NCT07146022Status: RECRUITING → ACTIVE_NOT_RECRUITING
MEDIUMAug 17, 2026NCT07146022Status: RECRUITING → ACTIVE_NOT_RECRUITING

Frequently asked questions about VDPHL01

What is VDPHL01 used for?

VDPHL01 is an investigational small molecule being developed for androgenetic alopecia (AGA), also known as male or female pattern baldness. It is a hair growth agent that targets minoxidil. The drug is currently in Phase 3 clinical development and has not been approved by the FDA.

What does VDPHL01 target?

VDPHL01 targets minoxidil, a well-known hair growth agent. It is being studied as a treatment for androgenetic alopecia, which causes hair loss in both men and women. The drug is designed to address the underlying mechanisms of pattern baldness.

Who is developing VDPHL01?

VDPHL01 is being developed by Veradermics, Incorporated, a biopharmaceutical company. The company is conducting clinical trials to evaluate the safety and efficacy of VDPHL01 for the treatment of androgenetic alopecia in both male and female patients.

What phase is VDPHL01 in?

VDPHL01 is currently in Phase 3 clinical development. The company has completed Phase 2 trials and is now conducting Phase 3 studies to further evaluate the drug's safety and efficacy in treating androgenetic alopecia. The drug is investigational and not yet FDA approved.

What clinical trials is VDPHL01 in?

VDPHL01 is being studied in several clinical trials, including NCT06527365, NCT06724614, NCT06972264, and NCT07146022. These trials are evaluating the drug in males and females with androgenetic alopecia, with some studies specifically focused on male or female patients. All trials are active but not recruiting.

Is VDPHL01 the same as VDPHL01 QD?

Yes, VDPHL01 is also known as VDPHL01 QD. The 'QD' designation likely refers to a once-daily dosing regimen. Both names refer to the same investigational drug being developed by Veradermics for the treatment of androgenetic alopecia.