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Johnson & Johnson reports Q4 and Full-Year 2025 results

Key Takeaway: Johnson & Johnson reported strong financial results for Q4 and full-year 2025, highlighting significant growth in its Innovative Medicine and MedTech segments. The company emphasized its robust pipeline and portfolio, which are expected to drive continued growth. However, challenges such as the impact of STELARA in Immunology and uncertainties in future financial predictions were noted.
Price reaction · baseline $218.21 (2026-01-20 close) · hit pre-market · clean, no other JNJ news in the window
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Market Sentiment Analysis

POSITIVE FACTORS

  • Strong portfolio and pipeline driving growth.
  • Innovative products in key therapeutic areas.
  • Positive sales growth in Innovative Medicine and MedTech.

CONCERNS & RISKS

  • Impact from STELARA in Immunology offsetting growth.
  • Uncertainty in predicting future financial outcomes.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+34%
120-day peak, hindsight
Typical move
1.6%
average across 15 past catalysts
Lead asset
Canagliflozin
Phase 3 · Diabetes Mellitus, Type 2

Full Press Release Details

NEW BRUNSWICK, N.J.--(BUSINESS WIRE)--Johnson & Johnson (NYSE: JNJ) today announced results for fourth-quarter and full-year 2025. “2025 was a catapult year for Johnson & Johnson, fueled by the strongest portfolio and pipeline in our history,” said Joaquin Duato, Chairman and Chief Executive Officer, Johnson & Johnson. “Last year kicked off a new era of accelerated growth, driven by medical innovation that is transforming lives in our six key businesses: Oncology, Immunology, Neuroscience, Cardiovascular, Surgery, and Vision. In each of these important areas, our leadership is expanding driven by game-changing science and technology.”

Overall financial results

Q4 Full Year
($ in Millions, except EPS) 2025 2024 % Change 2025 2024 % Change
Reported Sales $24,564 $22,520 9.1% $94,193 $88,821 6.0%
Net Earnings $5,116 $3,431 49.1% $26,804 $14,066 90.6%
EPS (diluted) $2.10 $1.41 48.9% $11.03 $5.79 90.5%
Q4 Full Year
Non-GAAP* ($ in Millions, except EPS) 2025 2024 % Change 2025 2024 % Change
Operational Sales1,2 7.1% 5.3%
Adjusted Operational Sales1,3 6.1% 4.2%
Adjusted Net Earnings1,4 $6,009 $4,946 21.5% $26,215 $24,242 8.1%
Adjusted EPS (diluted)1,4 $2.46 $2.04 20.6% $10.79 $9.98 8.1%
Free Cash Flow5,6 ~$19,700 $19,842
1 Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules
2 Excludes the impact of translational currency
3 Excludes the net impact of acquisitions and divestitures and translational currency
4 Excludes intangible amortization expense and special items
5 Non-GAAP measure; defined as cash flow from operating activities, less additions to property, plant and equipment. Cash flow from operations, the most directly comparable GAAP financial measure, will be included in subsequent SEC filings.
6 Full year 2025 is estimated as of January 21, 2026.
Note: values may have been rounded

Regional sales results

Q4 % Change
($ in Millions) 2025 2024 Reported Operational1,2 Currency AdjustedOperational1,3
U.S. $14,195 $13,204 7.5% 7.5 - 5.7
International 10,369 9,316 11.3 6.6 4.7 6.8
Worldwide $24,564 $22,520 9.1% 7.1 2.0 6.1
Full Year % Change
($ in Millions) 2025 2024 Reported Operational1,2 Currency AdjustedOperational1,3
U.S. $53,752 $50,302 6.9% 6.9 - 4.9
International 40,441 38,519 5.0 3.4 1.6 3.3
Worldwide $94,193 $88,821 6.0% 5.3 0.7 4.2
1 Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules
2 Excludes the impact of translational currency
3 Excludes the net impact of acquisitions and divestitures and translational currency
Note: values may have been rounded

Segment sales results

Q4 % Change
($ in Millions) 2025 2024 Reported Operational1,2 Currency AdjustedOperational1,3
Innovative Medicine $15,763 $14,332 10.0% 7.9 2.1 6.2
MedTech 8,801 8,188 7.5 5.8 1.7 5.9
Worldwide $24,564 $22,520 9.1% 7.1 2.0 6.1
Full Year % Change
($ in Millions) 2025 2024 Reported Operational1,2 Currency AdjustedOperational1,3
Innovative Medicine $60,401 $56,964 6.0% 5.3 0.7 4.1
MedTech 33,792 31,857 6.1 5.4 0.7 4.3
Worldwide $94,193 $88,821 6.0% 5.3 0.7 4.2
1 Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules
2 Excludes the impact of translational currency
3 Excludes the net impact of acquisitions and divestitures and translational currency
Note: values may have been rounded

Full-year 2025 segment commentary:

Operational sales* reflected below excludes the impact of translational currency.

Innovative Medicine

Innovative Medicine worldwide operational sales grew 5.3%*, with net acquisitions and divestitures positively impacting growth by 1.2% primarily due to CAPLYTA. Growth was driven primarily by DARZALEX, CARVYKTI, ERLEADA, and RYBREVANT/LAZCLUZE in Oncology, TREMFYA and SIMPONI/SIMPONI ARIA in Immunology, and SPRAVATO in Neuroscience. Growth was partially offset by an approximate (1,040) basis points impact from STELARA in Immunology.

MedTech

MedTech worldwide operational sales grew 5.4%*, with net acquisitions and divestitures positively impacting growth by 1.1% primarily due to Shockwave. Growth was driven primarily by electrophysiology products and Abiomed in Cardiovascular and wound closure products in General Surgery.

Full-year 2026 guidance:

Johnson & Johnson does not provide GAAP financial measures on a forward-looking basis because the company is unable to predict with reasonable certainty the ultimate outcome of legal proceedings, unusual gains and losses, acquisition-related expenses, and purchase accounting fair value adjustments without unreasonable effort. These items are uncertain, depend on various factors, and could be material to Johnson & Johnson's results computed in accordance with GAAP.
($ in Billions, except EPS) January 2026
Adjusted Operational Sales1,2Change vs. Prior Year / Mid-point 5.4% – 6.4% / 5.9%
Operational Sales2/ Mid-pointChange vs. Prior Year / Mid-point $99.5B – $100.5B / $100.0B5.7% – 6.7% / 6.2%
Estimated Reported Sales3/ Mid-pointChange vs. Prior Year / Mid-point $100.0B – $101.0B / $100.5B6.2% – 7.2% / 6.7%
Adjusted Operational EPS (Diluted)2,4/ Mid-pointChange vs. Prior Year / Mid-point $11.28 – $11.48 / $11.384.5% – 6.5% / 5.5%
Adjusted EPS (Diluted)3,4/ Mid-pointChange vs. Prior Year / Mid-point $11.43 – $11.63 / $11.535.9% – 7.9% / 6.9%
1 Non-GAAP financial measure; excludes the net impact of acquisitions and divestitures
2 Non-GAAP financial measure; excludes the impact of translational currency
3 Calculated using Euro Average Rate: January 2026 = $1.17 (Illustrative purposes only)
4 Non-GAAP financial measure; excludes intangible amortization expense and special items
Note: percentages may have been rounded
Other modeling considerations will be provided on thewebcast.

Notable announcements in the quarter:

The information contained in this section should be read together with Johnson & Johnson’s other disclosures filed with the Securities and Exchange Commission, including its Current Reports on Form 8-K, Quarterly Reports on Form 10-Q and Annual Reports on Form 10-K. Copies of these filings are available online atwww.sec.gov,www.jnj.comor on request from Johnson & Johnson. The reader is also encouraged to review all other news releases and information available in the Investor Relations section of the company’s website atInvestor News, as well asInnovative Medicine Newsroom,MedTech News & Events, andwww.factsabouttalc.com.
Regulatory Johnson & Johnson Submits OTTAVA Robotic Surgical System to the U.S. Food and Drug Administration1 Press Release
Johnson & Johnson Receives FDA Approval for TRUFILL n‑BCA Liquid Embolic System for the Treatment of Symptomatic Chronic Subdural Hematoma Press Release
U.S. FDA Approval of RYBREVANT FASPRO (amivantamab and hyaluronidase-lpuj) Enables the Simplest, Shortest Administration Time for a First-Line Combination Regimen when Combined with LAZCLUZE (lazertinib) Press Release
U.S. FDA approves AKEEGA as the first precision therapy for BRCA2-mutated metastatic castration-sensitive prostate cancer with 54% reduction in disease progression vs standard of care Press Release
DARZALEX FASPRO is the first and only treatment approved by the U.S. FDA for patients with high-risk smoldering multiple myeloma Press Release
FDA approval of CAPLYTA (lumateperone) has the potential to reset treatment expectations, offering hope for remission in adults with major depressive disorder Press Release
Data Releases New clinical data highlights CAPLYTA (lumateperone) as a promising option for achieving remission in adults with major depressive disorder1 Press Release
TECVAYLI monotherapy demonstrates superior progression-free and overall survival versus standard of care as early as first relapse in patients with multiple myeloma predominantly refractory to anti-CD38 therapy and lenalidomide1 Press Release
RYBREVANT (amivantamab-vmjw) longer-term results show promising and durable responses in difficult-to-treat colorectal cancer1 Press Release
Johnson & Johnson unveils new data showing nipocalimab is the first and only investigational FcRn blocker with potential to reduce systemic lupus erythematosus (SLE) activity in a Phase 2 study1 Press Release
Unprecedented results from the Phase 3 MajesTEC-3 study support TECVAYLI plus DARZALEX FASPRO as a potential standard of care as early as second line for patients with relapsed/refractory multiple myeloma Press Release
Earlier use of CARVYKTI demonstrated lasting treatment-free remissions at 2.5 years in patients with relapsed or refractory multiple myeloma Press Release
Johnson & Johnson's INLEXZO (gemcitabine intravesical system) delivers 74 percent disease-free survival at one year in BCG-unresponsive, high-risk, papillary-only NMIBC Press Release
New long-term data reinforces TREMFYA (guselkumab) as the only IL-23 inhibitor proven to substantially inhibit structural joint damage in active psoriatic arthritis Press Release
Johnson & Johnson announces first head-to-head study comparing IMAAVY with an alternative FcRn blocker in generalized myasthenia gravis (gMG) at AANEM Annual Meeting Press Release
Icotrokinra maintains standout combination of therapeutic benefit and a favorable safety profile in once-daily pill through 28 weeks in ulcerative colitis Press Release
TREMFYA (guselkumab), the first and only IL-23 inhibitor with a fully subcutaneous treatment regimen, demonstrates durable remission in Crohn's disease at two years Press Release
Published in The Lancet: Nipocalimab significantly decreased Sjögren's disease (SjD) activity and severity through substantial reduction in Sjögren's-related autoantibodies Press Release
Icotrokinra long-term results affirm promise of targeted oral peptide with high rates of durable skin clearance and favorable safety profile in difficult-to-treat scalp and genital psoriasis Press Release
Subcutaneous amivantamab delivers promising 45 percent overall response rate with median duration of 7.2 months in recurrent or metastatic head and neck cancer Press Release
TECVAYLI plus DARZALEX FASPRO combination regimen significantly improves progression-free survival and overall survival versus standard of care Press Release
Other Johnson & Johnson Reaches Agreement with U.S. Government to Improve Access to Medicines and Lower Costs for Millions of Americans; Delivers on U.S. Manufacturing and Innovation Investments1 Press Release
Johnson & Johnson completes acquisition of Halda Therapeutics and its novel platform to revolutionize cancer treatment and enable next-generation oral therapies Press Release
Johnson & Johnson Announces Intent to Separate Its Orthopaedics Business Press Release
1Subsequent to the quarter

Webcast information:

Johnson & Johnson will conduct a conference call with investors to discuss this earnings release today at 8:30 a.m., Eastern Time. A simultaneous webcast of the call for investors and other interested parties may be accessed by visiting theJohnson & Johnson website. A replay and podcast will be available approximately two hours after the live webcast in the Investor Relations section of the company's website atevents-and-presentations.

About Johnson & Johnson:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more atwww.jnj.com.

Non-GAAP financial measures:

* “Operational sales growth” excluding the impact of translational currency, “adjusted operational sales growth” excluding the net impact of acquisitions and divestitures and translational currency, as well as “adjusted net earnings”, “adjusted diluted earnings per share” and “adjusted operational diluted earnings per share” excluding after-tax intangible amortization expense and special items, are non-GAAP financial measures and should not be considered replacements for, and should be read together with, the most comparable GAAP financial measures. Except for guidance measures, reconciliations of these non-GAAP financial measures to the most directly comparable GAAP financial measures can be found in the accompanying financial schedules of the earnings release and the Investor Relations section of the company's website atquarterly results.
Copies of the financial schedules accompanying this earnings release are available on the company’s website atquarterly results. These schedules include supplementary sales data, a condensed consolidated statement of earnings, reconciliations of non-GAAP financial measures, and sales of key products/franchises. Additional information on Johnson & Johnson, including adjusted income before tax by segment, anInnovative Medicine pipelineof selected compounds in late stage development and a copy of today’s earnings call presentation can also be found in the Investor Relations section of the company's website atquarterly results.

Note to investors concerning forward-looking statements:

This press release contains “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things: future operating and financial performance, product development, and market position and business strategy. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Johnson & Johnson. Risks and uncertainties include, but are not limited to: economic factors, such as interest rate and currency exchange rate fluctuations or changes to applicable laws and regulations; competition, including technological advances, new products and patents attained by competitors; challenges inherent in new product research and development, including uncertainty of clinical success and obtaining regulatory approvals; uncertainty of commercial success for new and existing products; challenges to patents; the impact of patent expirations; the ability of the Company to successfully execute strategic plans, including restructuring plans; the impact of business combinations and divestitures; manufacturing difficulties or delays, internally or within the supply chain; product efficacy or safety concerns resulting in product recalls or regulatory action; significant adverse litigation or government action, including related to product liability claims; changes to applicable laws and regulations, including tax laws and global health care reforms; trends toward health care cost containment; changes in behavior and spending patterns of purchasers of health care products and services; financial instability of international economies and legal systems and sovereign risk; and increased scrutiny of the health care industry by government agencies. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson’s most recent Annual Report on Form 10-K, including in the sections captioned “Cautionary Note Regarding Forward-Looking Statements” and “Item 1A. Risk Factors,” and in Johnson & Johnson’s subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. Copies of these filings are available online atwww.sec.gov,www.jnj.com,investor.jnj.com, or on request from Johnson & Johnson. Any forward-looking statement made in this release speaks only as of the date of this release. Johnson & Johnson does not undertake to update any forward-looking statement as a result of new information or future events or developments.
Johnson & Johnson and Subsidiaries
Supplementary Sales Data
(Unaudited; Dollars in Millions) FOURTH QUARTER TWELVE MONTHS
Percent Change Percent Change
2025 2024 Total Operations Currency 2025 2024 Total Operations Currency
Sales to customers by
segment of business
Innovative Medicine
U.S. $ 9,689 8,977 7.9 % 7.9 - $ 36,344 33,970 7.0 % 7.0 -
International 6,074 5,355 13.4 7.9 5.5 24,057 22,994 4.6 2.9 1.7
15,763 14,332 10.0 7.9 2.1 60,401 56,964 6.0 5.3 0.7
MedTech
U.S. 4,506 4,227 6.6 6.6 - 17,408 16,332 6.6 6.6 -
International 4,295 3,961 8.5 4.9 3.6 16,384 15,525 5.5 4.1 1.4
8,801 8,188 7.5 5.8 1.7 33,792 31,857 6.1 5.4 0.7
U.S. 14,195 13,204 7.5 7.5 - 53,752 50,302 6.9 6.9 -
International 10,369 9,316 11.3 6.6 4.7 40,441 38,519 5.0 3.4 1.6
Worldwide $ 24,564 22,520 9.1 % 7.1 2.0 $ 94,193 88,821 6.0 % 5.3 0.7
Note:Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.
Johnson & Johnson and Subsidiaries
Supplementary Sales Data
(Unaudited; Dollars in Millions) FOURTH QUARTER TWELVE MONTHS
Percent Change Percent Change
2025 2024 Total Operations Currency 2025 2024 Total Operations Currency
Sales to customers by
geographic area
U.S. $ 14,195 13,204 7.5 % 7.5 - $ 53,752 50,302 6.9 % 6.9 -
Europe 5,598 4,921 13.8 5.2 8.6 21,535 20,212 6.5 2.4 4.1
Western Hemisphere excluding U.S. 1,271 1,135 12.0 11.0 1.0 4,875 4,714 3.4 8.4 (5.0 )
Asia-Pacific, Africa 3,500 3,260 7.4 7.2 0.2 14,031 13,593 3.2 3.1 0.1
International 10,369 9,316 11.3 6.6 4.7 40,441 38,519 5.0 3.4 1.6
Worldwide $ 24,564 22,520 9.1 % 7.1 2.0 $ 94,193 88,821 6.0 % 5.3 0.7
Note:Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely.
Johnson & Johnson and Subsidiaries
Condensed Consolidated Statement of Earnings
(Unaudited; in Millions Except Per Share Figures) FOURTH QUARTER
2025 2024 PercentIncrease(Decrease)
Amount Percentto Sales Amount Percentto Sales
Sales to customers $ 24,564 100.0 $ 22,520 100.0 9.1
Cost of products sold 7,968 32.4 7,128 31.6 11.8
Gross Profit 16,596 67.6 15,392 68.4 7.8
Selling, marketing and administrative expenses 6,753 27.5 6,453 28.6 4.6
Research and development expense 4,252 17.3 5,298 23.5 (19.7 )
In-process research and development impairments 81 0.3 17 0.1
Interest (income) expense, net (23 ) (0.1 ) (144 ) (0.6 )
Other (income) expense, net 483 2.0 (161 ) (0.7 )
Restructuring 84 0.4 42 0.2
Earnings before provision for taxes on income 4,966 20.2 3,887 17.3 27.8
(Benefit from)/Provision for taxes on income (150 ) (0.6 ) 456 2.1 (132.9 )
Net earnings $ 5,116 20.8 $ 3,431 15.2 49.1
Net earnings per share (Diluted) $ 2.10 $ 1.41 48.9
Average shares outstanding (Diluted) 2,439.0 2,427.1
Effective tax rate (3.0 ) % 11.7 %
Adjusted earnings before provision for taxes and net earnings (1)
Earnings before provision for taxes on income $ 7,046 28.7 $ 5,421 24.1 30.0
Net earnings $ 6,009 24.5 $ 4,946 22.0 21.5
Net earnings per share (Diluted) $ 2.46 $ 2.04 20.6
Effective tax rate 14.7 % 8.8 %
(1) See Reconciliation of Non-GAAP Financial Measures.
Johnson & Johnson and Subsidiaries
Condensed Consolidated Statement of Earnings
(Unaudited; in Millions Except Per Share Figures) TWELVE MONTHS
2025 2024 PercentIncrease(Decrease)
Amount Percentto Sales Amount Percentto Sales
Sales to customers $ 94,193 100.0 $ 88,821 100.0 6.0
Cost of products sold 30,256 32.1 27,471 30.9 10.1
Gross Profit 63,937 67.9 61,350 69.1 4.2
Selling, marketing and administrative expenses 23,676 25.1 22,869 25.7 3.5
Research and development expense 14,665 15.6 17,232 19.4 (14.9 )
In-process research and development impairments 81 0.1 211 0.2
Interest (income) expense, net (85 ) (0.1 ) (577 ) (0.6 )
Other (income) expense, net (7,209 ) (7.6 ) 4,694 5.3
Restructuring 228 0.2 234 0.3
Earnings before provision for taxes on income 32,581 34.6 16,687 18.8 95.2
Provision for taxes on income 5,777 6.1 2,621 3.0 120.4
Net earnings $ 26,804 28.5 $ 14,066 15.8 90.6
Net earnings per share (Diluted) $ 11.03 $ 5.79 90.5
Average shares outstanding (Diluted) 2,429.4 2,429.4
Effective tax rate 17.7 % 15.7 %
Adjusted earnings before provision for taxes and net earnings (1)
Earnings before provision for taxes on income $ 31,681 33.6 $ 28,979 32.6 9.3
Net earnings $ 26,215 27.8 $ 24,242 27.3 8.1
Net earnings per share (Diluted) $ 10.79 $ 9.98 8.1
Effective tax rate 17.3 % 16.3 %
(1) See Reconciliation of Non-GAAP Financial Measures.
Johnson & Johnson and Subsidiaries
Reconciliation of Non-GAAP Financial Measures
Fourth Quarter Twelve Months Ended
(Dollars in Millions Except Per Share Data) 2025 2024 2025 2024
Net Earnings, after tax- as reported $5,116 $3,431 $26,804 $14,066
Pre-tax Adjustments
Litigation related 854 (16) (6,040) 5,450
Intangible Asset Amortization expense 1,186 1,171 4,621 4,526
Restructuring related1 210 62 512 269
Acquisition, integration and divestiture related (190) 298 285 1,226
IPR&D impairments 81 17 81 211
(Gains)/losses on securities (100) (68) (427) 306
Orthopaedics Separation related 48 - 48 -
COVID-19 Vaccine related costs - 23 - 100
Medical Device Regulation - 47 - 204
Other (9) - 20 -
Tax Adjustments
Tax impact on special item adjustments2 (445) (80) 381 (2,135)
Tax legislation and other tax related (742) 61 (70) 19
Adjusted Net Earnings, after tax $6,009 $4,946 $26,215 $24,242
Average shares outstanding (Diluted) 2,439.0 2,427.1 2,429.4 2,429.4
Adjusted net earnings per share (Diluted) $2.46 $2.04 $10.79 $9.98
Operational adjusted net earnings per share (Diluted) $2.35 $10.58
Notes:
1 In fiscal 2023, the company completed a prioritization of its research and development (R&D) investment within the Innovative Medicine segment to focus on the most promising medicines with the greatest benefit to patients. This resulted in the exit of certain programs within therapeutic areas. The R&D program exits were primarily in infectious diseases and vaccines including the discontinuation of its respiratory syncytial virus (RSV) adult vaccine program, hepatitis and HIV development. The restructuring expense of $102 million in fiscal 2024 included the termination of partnered and non-partnered program costs, asset impairments and asset divestments. This program was completed in Q4 2024.
In fiscal 2023, the company initiated a restructuring program of its Orthopaedics franchise within the MedTech segment to streamline operations by exiting certain markets, product lines and distribution network arrangements. The restructuring expense of $162 million in the fiscal fourth quarter of 2025 ($307 million Q4 2025 YTD) and $60 million in the fiscal fourth quarter of 2024 ($167 million Q4 2024 YTD) primarily includes costs related to market and product exits. This program was substantially completed in Q4 2025.
In fiscal 2025, the company initiated a restructuring program of its Surgery franchise within the MedTech segment to simplify and focus operations by exiting certain non-strategic product lines and optimize select sites across the network. The restructuring expense of $48 million in the fiscal fourth quarter of 2025 ($205 million Q4 2025 YTD) primarily includes costs related to asset impairments and market and product exits. This program is expected to be substantially completed by the end of fiscal year 2026.
2 The tax impact related to special item adjustments reflects the current and deferred income taxes associated with the above pre-tax special items in arriving at adjusted earnings.
Johnson & Johnson and Subsidiaries
Reconciliation of Non-GAAP Financial Measure
Adjusted Operational Sales Growth
FOURTH QUARTER 2025 ACTUAL vs. 2024 ACTUAL
Segments
Innovative Medicine MedTech Total
WW As Reported 10.0% 7.5% 9.1%
U.S. 7.9% 6.6% 7.5%
International 13.4% 8.5% 11.3%
WW Currency 2.1 1.7 2.0
U.S. - - -
International 5.5 3.6 4.7
WW Operational 7.9% 5.8% 7.1%
U.S. 7.9% 6.6% 7.5%
International 7.9% 4.9% 6.6%
Caplyta (1.7) (1.1)
U.S. (2.8) (1.9)
International 0.0 0.0
All Other Acquisitions and Divestitures (A&D) 0.0 0.1 0.1
U.S. 0.0 0.1 0.1
International 0.1 0.2 0.2
WW Adjusted Operational Ex A&D 6.2% 5.9% 6.1%
U.S. 5.1% 6.7% 5.7%
International 8.0% 5.1% 6.8%
Note:Percentages are based on actual, non-rounded figures and may not sum
Johnson & Johnson and Subsidiaries
Reconciliation of Non-GAAP Financial Measure
Adjusted Operational Sales Growth
TWELVE MONTHS 2025 ACTUAL vs. 2024 ACTUAL
Segments
Innovative Medicine MedTech Total
WW As Reported 6.0% 6.1% 6.0%
U.S. 7.0% 6.6% 6.9%
International 4.6% 5.5% 5.0%
WW Currency 0.7 0.7 0.7
U.S. - - -
International 1.7 1.4 1.6
WW Operational 5.3% 5.4% 5.3%
U.S. 7.0% 6.6% 6.9%
International 2.9% 4.1% 3.4%
Shockwave (1.4) (0.5)
U.S. (2.1) (0.7)
International (0.5) (0.2)
Caplyta (1.2) (0.7)
U.S. (2.1) (1.4)
International 0.0 0.0
All Other Acquisitions and Divestitures (A&D) 0.0 0.3 0.1
U.S. 0.0 0.3 0.1
International 0.1 0.2 0.1
WW Adjusted Operational Ex A&D 4.1% 4.3% 4.2%
U.S. 4.9% 4.8% 4.9%
International 3.0% 3.8% 3.3%
Note:Percentages are based on actual, non-rounded figures and may not sum
REPORTED SALES vs. PRIOR PERIOD ($MM) REPORTED SALES vs. PRIOR PERIOD ($MM)
FOURTH QUARTER TWELVE MONTHS
% Change % Change
INNOVATIVE MEDICINE SEGMENT(2) 2025 2024 Reported Operational(1) Currency 2025 2024 Reported Operational(1) Currency
ONCOLOGY
US $ 3,793 3,019 25.6 % 25.6 % - $ 13,659 10,854 25.8 % 25.8 % -
Intl 3,069 2,476 23.9 % 17.3 % 6.6 % 11,721 9,926 18.1 % 15.6 % 2.5 %
WW 6,861 5,497 24.8 % 21.9 % 2.9 % 25,380 20,781 22.1 % 20.9 % 1.2 %
CARVYKTI
US 420 304 38.2 % 38.2 % - 1,492 869 71.6 % 71.6 % -
Intl 135 31 * * * 395 94 * * *
WW 555 334 65.8 % 63.2 % 2.6 % 1,887 963 95.9 % 94.3 % 1.6 %
DARZALEX
US 2,332 1,799 29.6 % 29.6 % - 8,266 6,588 25.5 % 25.5 % -
Intl 1,571 1,285 22.3 % 16.2 % 6.1 % 6,085 5,082 19.7 % 17.5 % 2.2 %
WW 3,903 3,084 26.6 % 24.1 % 2.5 % 14,351 11,670 23.0 % 22.0 % 1.0 %
ERLEADA
US 405 342 18.6 % 18.6 % - 1,453 1,282 13.4 % 13.4 % -
Intl 554 442 25.3 % 17.5 % 7.8 % 2,121 1,717 23.5 % 20.1 % 3.4 %
WW 959 784 22.4 % 18.0 % 4.4 % 3,574 2,999 19.2 % 17.2 % 2.0 %
IMBRUVICA
US 207 250 (17.4 )% (17.4 )% - 892 1,020 (12.5 )% (12.5 )% -
Intl 478 481 (0.8 )% (7.5 )% 6.7 % 1,931 2,018 (4.3 )% (6.7 )% 2.4 %
WW 684 731 (6.5 )% (10.9 )% 4.4 % 2,823 3,038 (7.1 )% (8.6 )% 1.5 %
RYBREVANT / LAZCLUZE(3)
US 146 101 45.6 % 45.6 % - 534 257 * * -
Intl 70 21 * * * 200 70 * * *
WW 216 122 78.0 % 76.5 % 1.5 % 734 327 * * *
TALVEY
US 105 68 53.8 % 53.8 % - 340 241 40.9 % 40.9 % -
Intl 44 17 * * * 123 46 * * *
WW 149 85 75.8 % 73.1 % 2.7 % 463 287 61.3 % 60.3 % 1.0 %
TECVAYLI
US 110 108 2.7 % 2.7 % - 444 418 6.3 % 6.3 % -
Intl 66 38 72.2 % 65.1 % 7.1 % 226 131 72.8 % 70.4 % 2.4 %
WW 176 146 20.8 % 18.9 % 1.9 % 670 549 22.1 % 21.5 % 0.6 %
ZYTIGA / abiraterone acetate
US 5 9 (41.4 )% (41.4 )% - 23 34 (33.2 )% (33.2 )% -
Intl 115 127 (9.9 )% (11.1 )% 1.2 % 480 597 (19.7 )% (20.5 )% 0.8 %
WW 119 135 (11.9 )% (13.0 )% 1.1 % 502 631 (20.4 )% (21.2 )% 0.8 %
OTHER ONCOLOGY
US 61 39 54.8 % 54.8 % - 214 145 47.5 % 47.5 % -
Intl 39 36 8.4 % 3.0 % 5.4 % 162 172 (6.0 )% (7.8 )% 1.8 %
WW 100 75 32.9 % 30.3 % 2.6 % 376 317 18.5 % 17.5 % 1.0 %
See footnotes at end of schedule
REPORTED SALES vs. PRIOR PERIOD ($MM) REPORTED SALES vs. PRIOR PERIOD ($MM)
FOURTH QUARTER TWELVE MONTHS
% Change % Change
2025 2024 Reported Operational(1) Currency 2025 2024 Reported Operational(1) Currency
IMMUNOLOGY
US $ 2,495 2,856 (12.6 )% (12.6 )% - $ 9,872 11,355 (13.1 )% (13.1 )% -
Intl 1,364 1,383 (1.4 )% (5.5 )% 4.1 % 5,856 6,473 (9.5 )% (10.2 )% 0.7 %
WW 3,860 4,238 (8.9 )% (10.3 )% 1.4 % 15,728 17,828 (11.8 )% (12.0 )% 0.2 %
REMICADE
US 248 231 7.1 % 7.1 % - 1,171 1,009 16.0 % 16.0 % -
US Exports(4) 11 9 17.1 % 17.1 % - 74 98 (24.8 )% (24.8 )% -
Intl 110 117 (5.6 )% (7.3 )% 1.7 % 523 497 5.3 % 6.2 % (0.9 )%
WW 370 359 3.2 % 2.6 % 0.6 % 1,768 1,605 10.2 % 10.5 % (0.3 )%
SIMPONI / SIMPONI ARIA
US 287 262 9.6 % 9.6 % - 1,193 1,082 10.3 % 10.3 % -
Intl 345 321 7.4 % 3.7 % 3.7 % 1,475 1,108 33.1 % 32.8 % 0.3 %
WW 632 583 8.4 % 6.4 % 2.0 % 2,668 2,190 21.8 % 21.7 % 0.1 %
STELARA
US 766 1,699 (54.9 )% (54.9 )% - 3,847 6,720 (42.7 )% (42.7 )% -
Intl 462 650 (28.8 )% (32.3 )% 3.5 % 2,230 3,641 (38.7 )% (39.3 )% 0.6 %
WW 1,230 2,349 (47.7 )% (48.6 )% 0.9 % 6,078 10,361 (41.3 )% (41.5 )% 0.2 %
TREMFYA
US 1,145 654 75.1 % 75.1 % - 3,529 2,443 44.5 % 44.5 % -
Intl 445 295 50.9 % 44.0 % 6.9 % 1,626 1,227 32.5 % 30.4 % 2.1 %
WW 1,589 949 67.6 % 65.4 % 2.2 % 5,155 3,670 40.5 % 39.8 % 0.7 %
OTHER IMMUNOLOGY
US 39 0 * * - 59 3 * * -
Intl 2 0 * * * 2 0 * * *
WW 40 0 * * * 61 3 * * *
NEUROSCIENCE
US 1,439 1,148 25.4 % 25.4 % - 5,151 4,398 17.1 % 17.1 % -
Intl 675 628 7.6 % 4.3 % 3.3 % 2,686 2,718 (1.2 )% (1.8 )% 0.6 %
WW 2,115 1,775 19.1 % 17.9 % 1.2 % 7,837 7,115 10.1 % 9.9 % 0.2 %
CAPLYTA(5)
US 249 - * * - 700 - * * -
Intl - - - - - - - - - -
WW 249 - * * - 700 - * * -
CONCERTA / Methylphenidate
US 6 33 (79.6 )% (79.6 )% - 82 134 (38.6 )% (38.6 )% -
Intl 126 125 (0.3 )% (1.4 )% 1.1 % 502 507 (1.2 )% (0.7 )% (0.5 )%
WW 132 159 (17.1 )% (17.8 )% 0.7 % 584 641 (9.0 )% (8.6 )% (0.4 )%
INVEGA SUSTENNA / XEPLION /INVEGA TRINZA / TREVICTA
US 704 796 (11.5 )% (11.5 )% - 2,725 3,125 (12.8 )% (12.8 )% -
Intl 281 267 5.2 % 1.9 % 3.3 % 1,085 1,097 (1.1 )% (1.8 )% 0.7 %
WW 986 1,063 (7.3 )% (8.2 )% 0.9 % 3,810 4,222 (9.8 )% (9.9 )% 0.1 %
SPRAVATO
US 438 269 63.0 % 63.0 % - 1,485 929 59.9 % 59.9 % -
Intl 64 28 * * * 210 148 41.9 % 39.1 % 2.8 %
WW 503 297 69.0 % 67.8 % 1.2 % 1,696 1,077 57.4 % 57.0 % 0.4 %
OTHER NEUROSCIENCE
US 40 49 (18.3 )% (18.3 )% - 159 210 (24.5 )% (24.5 )% -
Intl 205 206 (0.7 )% (4.3 )% 3.6 % 889 965 (7.9 )% (8.7 )% 0.8 %
WW 245 255 (4.1 )% (6.9 )% 2.8 % 1,048 1,175 (10.9 )% (11.5 )% 0.6 %
See footnotes at end of schedule
REPORTED SALES vs. PRIOR PERIOD ($MM) REPORTED SALES vs. PRIOR PERIOD ($MM)
FOURTH QUARTER TWELVE MONTHS
% Change % Change
2025 2024 Reported Operational(1) Currency 2025 2024 Reported Operational(1) Currency
PULMONARY HYPERTENSION
US $ 865 819 5.7 % 5.7 % - $ 3,223 3,143 2.6 % 2.6 % -
Intl 319 274 16.4 % 12.2 % 4.2 % 1,214 1,140 6.5 % 4.9 % 1.6 %
WW 1,184 1,092 8.4 % 7.4 % 1.0 % 4,437 4,282 3.6 % 3.2 % 0.4 %
OPSUMIT / OPSYNVI
US 458 408 11.9 % 11.9 % - 1,633 1,557 4.8 % 4.8 % -
Intl 185 162 14.8 % 10.9 % 3.9 % 692 668 3.7 % 2.1 % 1.6 %
WW 643 570 12.7 % 11.6 % 1.1 % 2,325 2,225 4.5 % 4.0 % 0.5 %
UPTRAVI
US 397 391 1.6 % 1.6 % - 1,536 1,511 1.7 % 1.7 % -
Intl 94 75 26.9 % 20.8 % 6.1 % 366 307 19.4 % 17.4 % 2.0 %
WW 491 465 5.7 % 4.7 % 1.0 % 1,902 1,817 4.7 % 4.3 % 0.4 %
OTHER PULMONARY HYPERTENSION
US 10 19 (43.7 )% (43.7 )% - 54 75 (27.0 )% (27.0 )% -
Intl 39 38 2.6 % 1.2 % 1.4 % 155 165 (6.2 )% (6.8 )% 0.6 %
WW 49 57 (12.5 )% (13.5 )% 1.0 % 209 240 (12.7 )% (13.0 )% 0.3 %
INFECTIOUS DISEASES
US 303 331 (8.5 )% (8.5 )% - 1,264 1,354 (6.6 )% (6.6 )% -
Intl 505 443 13.9 % 5.6 % 8.3 % 1,977 2,042 (3.2 )% (6.5 )% 3.3 %
WW 807 774 4.3 % (0.4 )% 4.7 % 3,241 3,396 (4.6 )% (6.5 )% 1.9 %
EDURANT / rilpivirine
US 5 7 (39.1 )% (39.1 )% - 26 31 (18.4 )% (18.4 )% -
Intl 379 315 20.6 % 11.1 % 9.5 % 1,461 1,241 17.7 % 13.0 % 4.7 %
WW 383 322 19.2 % 9.9 % 9.3 % 1,486 1,272 16.9 % 12.2 % 4.7 %
PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA
US 294 321 (8.4 )% (8.4 )% - 1,226 1,311 (6.5 )% (6.5 )% -
Intl 89 86 3.6 % (2.9 )% 6.5 % 353 401 (11.9 )% (13.7 )% 1.8 %
WW 383 407 (5.8 )% (7.2 )% 1.4 % 1,579 1,712 (7.7 )% (8.1 )% 0.4 %
OTHER INFECTIOUS DISEASES
US 4 1 92.9 % 92.9 % - 12 11 6.6 % 6.6 % -
Intl 37 43 (14.5 )% (18.0 )% 3.5 % 163 401 (59.3 )% (59.5 )% 0.2 %
WW 40 45 (9.9 )% (13.2 )% 3.3 % 175 412 (57.5 )% (57.7 )% 0.2 %
CARDIOVASCULAR / METABOLISM / OTHER
US 794 805 (1.4 )% (1.4 )% - 3,175 2,866 10.8 % 10.8 % -
Intl 142 153 (6.3 )% (10.7 )% 4.4 % 603 696 (13.3 )% (13.8 )% 0.5 %
WW 936 957 (2.2 )% (2.9 )% 0.7 % 3,778 3,562 6.1 % 6.0 % 0.1 %
XARELTO
US 687 676 1.7 % 1.7 % - 2,633 2,373 11.0 % 11.0 % -
Intl - - - - - - - - - -
WW 687 676 1.7 % 1.7 % - 2,633 2,373 11.0 % 11.0 % -
OTHER
US 107 130 (17.4 )% (17.4 )% - 542 494 9.8 % 9.8 % -
Intl 142 153 (6.3 )% (10.7 )% 4.4 % 603 696 (13.3 )% (13.8 )% 0.5 %
WW 249 281 (11.4 )% (13.8 )% 2.4 % 1,145 1,189 (3.7 )% (4.0 )% 0.3 %
TOTAL INNOVATIVE MEDICINE
US 9,689 8,977 7.9 % 7.9 % - 36,344 33,970 7.0 % 7.0 % -
Intl 6,074 5,355 13.4 % 7.9 % 5.5 % 24,057 22,994 4.6 % 2.9 % 1.7 %
WW $ 15,763 14,332 10.0 % 7.9 % 2.1 % $ 60,401 56,964 6.0 % 5.3 % 0.7 %
See footnotes at end of schedule
REPORTED SALES vs. PRIOR PERIOD ($MM) REPORTED SALES vs. PRIOR PERIOD ($MM)
FOURTH QUARTER TWELVE MONTHS
% Change % Change
MEDTECH SEGMENT(2) 2025 2024 Reported Operational(1) Currency 2025 2024 Reported Operational(1) Currency
CARDIOVASCULAR
US $ 1,374 1,221 12.5 % 12.5 % - $ 5,305 4,513 17.5 % 17.5 % -
Intl 925 841 10.1 % 6.8 % 3.3 % 3,623 3,194 13.4 % 11.9 % 1.5 %
WW 2,299 2,062 11.5 % 10.1 % 1.4 % 8,928 7,707 15.8 % 15.2 % 0.6 %
ELECTROPHYSIOLOGY
US 746 681 9.5 % 9.5 % - 2,891 2,738 5.6 % 5.6 % -
Intl 679 640 6.2 % 3.2 % 3.0 % 2,743 2,529 8.5 % 7.3 % 1.2 %
WW 1,425 1,321 7.9 % 6.5 % 1.4 % 5,634 5,267 7.0 % 6.4 % 0.6 %
ABIOMED
US 358 308 16.5 % 16.5 % - 1,393 1,213 14.9 % 14.9 % -
Intl 102 77 33.1 % 25.4 % 7.7 % 358 284 26.4 % 22.0 % 4.4 %
WW 460 384 19.8 % 18.3 % 1.5 % 1,751 1,496 17.1 % 16.2 % 0.9 %
SHOCKWAVE
US 238 202 18.0 % 18.0 % - 897 442 * * -
Intl 80 56 42.3 % 40.7 % 1.6 % 249 122 * * *
WW 318 258 23.3 % 22.9 % 0.4 % 1,146 564 * * *
OTHER CARDIOVASCULAR
US 31 31 (0.1 )% (0.1 )% - 124 120 3.1 % 3.1 % -
Intl 64 68 (6.7 )% (8.8 )% 2.1 % 273 260 4.9 % 4.1 % 0.8 %
WW 95 99 (4.6 )% (6.1 )% 1.5 % 397 380 4.3 % 3.8 % 0.5 %
ORTHOPAEDICS
US 1,520 1,460 4.2 % 4.2 % - 5,720 5,689 0.5 % 0.5 % -
Intl 918 856 7.3 % 2.3 % 5.0 % 3,538 3,470 2.0 % (0.2 )% 2.2 %
WW 2,438 2,315 5.3 % 3.5 % 1.8 % 9,258 9,158 1.1 % 0.3 % 0.8 %
HIPS
US 284 272 4.3 % 4.3 % - 1,080 1,057 2.1 % 2.1 % -
Intl 154 146 5.5 % 0.4 % 5.1 % 594 581 2.2 % 0.1 % 2.1 %
WW 439 418 4.7 % 2.9 % 1.8 % 1,674 1,638 2.1 % 1.4 % 0.7 %
KNEES
US 251 238 5.1 % 5.1 % - 924 922 0.2 % 0.2 % -
Intl 181 160 13.7 % 9.2 % 4.5 % 663 623 6.5 % 4.6 % 1.9 %
WW 432 398 8.6 % 6.8 % 1.8 % 1,587 1,545 2.7 % 2.0 % 0.7 %
TRAUMA
US 543 514 5.6 % 5.6 % - 2,058 2,013 2.2 % 2.2 % -
Intl 270 250 7.9 % 2.7 % 5.2 % 1,088 1,036 5.0 % 2.7 % 2.3 %
WW 813 764 6.4 % 4.7 % 1.7 % 3,146 3,049 3.2 % 2.4 % 0.8 %
SPINE, SPORTS & OTHER
US 442 434 1.9 % 1.9 % - 1,658 1,696 (2.2 )% (2.2 )% -
Intl 312 300 4.2 % (0.7 )% 4.9 % 1,193 1,230 (3.0 )% (5.3 )% 2.3 %
WW 756 735 2.8 % 0.8 % 2.0 % 2,852 2,926 (2.5 )% (3.5 )% 1.0 %
See footnotes at end of schedule
REPORTED SALES vs. PRIOR PERIOD ($MM) REPORTED SALES vs. PRIOR PERIOD ($MM)
FOURTH QUARTER TWELVE MONTHS
% Change % Change
2025 2024 Reported Operational(1) Currency 2025 2024 Reported Operational(1) Currency
SURGERY
US $ 1,081 1,038 4.2 % 4.2 % - $ 4,157 4,003 3.9 % 3.9 % -
Intl 1,563 1,469 6.4 % 3.4 % 3.0 % 5,980 5,842 2.4 % 1.5 % 0.9 %
WW 2,644 2,507 5.5 % 3.7 % 1.8 % 10,137 9,845 3.0 % 2.5 % 0.5 %
ADVANCED
US 489 478 2.5 % 2.5 % - 1,900 1,838 3.4 % 3.4 % -
Intl 687 673 1.9 % (0.8 )% 2.7 % 2,678 2,650 1.0 % 0.1 % 0.9 %
WW 1,175 1,151 2.2 % 0.6 % 1.6 % 4,577 4,488 2.0 % 1.5 % 0.5 %
GENERAL
US 592 560 5.6 % 5.6 % - 2,258 2,165 4.3 % 4.3 % -
Intl 876 795 10.2 % 6.9 % 3.3 % 3,302 3,192 3.4 % 2.7 % 0.7 %
WW 1,468 1,357 8.3 % 6.3 % 2.0 % 5,560 5,358 3.8 % 3.3 % 0.5 %
VISION
US 531 509 4.3 % 4.3 % - 2,225 2,128 4.6 % 4.6 % -
Intl 889 794 11.9 % 8.5 % 3.4 % 3,243 3,018 7.4 % 5.9 % 1.5 %
WW 1,420 1,303 8.9 % 6.8 % 2.1 % 5,468 5,146 6.3 % 5.3 % 1.0 %
CONTACT LENSES / OTHER
US 417 396 5.3 % 5.3 % - 1,754 1,684 4.1 % 4.1 % -
Intl 592 541 9.3 % 5.3 % 4.0 % 2,157 2,049 5.3 % 3.2 % 2.1 %
WW 1,008 937 7.6 % 5.3 % 2.3 % 3,910 3,733 4.8 % 3.6 % 1.2 %
SURGICAL
US 113 113 0.6 % 0.6 % - 471 444 6.1 % 6.1 % -
Intl 297 252 17.7 % 15.3 % 2.4 % 1,086 969 12.1 % 11.6 % 0.5 %
WW 411 365 12.4 % 10.8 % 1.6 % 1,558 1,413 10.2 % 9.9 % 0.3 %
TOTAL MEDTECH
US 4,506 4,227 6.6 % 6.6 % - 17,408 16,332 6.6 % 6.6 % -
Intl 4,295 3,961 8.5 % 4.9 % 3.6 % 16,384 15,525 5.5 % 4.1 % 1.4 %
WW $ 8,801 8,188 7.5 % 5.8 % 1.7 % $ 33,792 31,857 6.1 % 5.4 % 0.7 %
Note:Columns and rows within tables may not add due to rounding. Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely
* Percentage greater than 100% or not meaningful
(1) Operational growth excludes the effect of translational currency
(2) Unaudited
(3) Includes the sales of RYBREVANT and RYBREVANT + LAZCLUZE
(4) Reported as U.S. sales
(5) Acquired with Intra-Cellular Therapies on April 2, 2025
Johnson & Johnson and Subsidiaries
GAAP to Non-GAAP Reconciliation
$ in Millions
Quarter to Date
Innovative Medicine Fourth QuarterDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Fourth QuarterDec. 28, 2025Non-GAAP
Cost of products sold $ 3,976 (704 ) (11 ) 3,261
Selling, marketing and admin expenses 3,456 3,456
Research and development expense 3,466 3,466
Other segment items (193 ) 16 (11 ) (52 ) 101 4 (135 )
Adjusted Income Before Tax by Segment 5,058 704 (16 ) 11 - 63 (101 ) - - (4 ) 5,715
MedTech Fourth QuarterDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Fourth QuarterDec. 28, 2025Non-GAAP
Cost of products sold $ 3,973 (482 ) (56 ) 3,435
Selling, marketing and admin expenses 3,035 3,035
Research and development expense 786 786
Other segment items 806 (818 ) (70 ) (154 ) 290 (1 ) (48 ) 5 10
Adjusted Income Before Tax by Segment 201 482 818 70 210 (290 ) 1 48 - (5 ) 1,535
Expenses not allocated to segments Fourth QuarterDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Fourth QuarterDec. 28, 2025Non-GAAP
Cost of products sold $ 19 19
Selling, marketing and admin expenses 262 262
Research and development expense - -
Other segment items 12 (52 ) (37 ) (77 )
Adjusted Income Before Tax by Segment (293 ) - 52 - - 37 - - - - (204 )
Johnson & Johnson Consolidated Fourth QuarterDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Fourth QuarterDec. 28, 2025Non-GAAP
Cost of products sold $ 7,968 (1,186 ) (56 ) (11 ) 6,715
Selling, marketing and admin expenses 6,753 6,753
Research and development expense 4,252 4,252
Other (Income) / Expense 483 (854 ) (70 ) 201 100 (48 ) 9 (179 )
In-process research and development impairments 81 (81 ) -
Interest (Income)/Expense (23 ) (23 )
Restructuring 84 (84 ) -
Adjusted Income Before Tax 4,966 1,186 854 81 210 (190 ) (100 ) 48 - (9 ) 7,046
Provision for taxes on income (150 ) 226 32 18 35 149 (23 ) 11 742 (3 ) 1,037
Net Earnings $ 5,116 960 822 63 175 (339 ) (77 ) 37 (742 ) (6 ) 6,009
Johnson & Johnson and Subsidiaries
GAAP to Non-GAAP Reconciliation
$ in Millions
Quarter to Date
Innovative Medicine Fourth QuarterDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Fourth QuarterDec. 29, 2024Non-GAAP
Cost of products sold $ 3,514 (685 ) 2,829
Selling, marketing and admin expenses 3,312 3,312
Research and development expense 3,698 (6 ) 3,692
Other segment items (201 ) 41 (17 ) (2 ) (12 ) 50 (17 ) (158 )
Adjusted Income Before Tax by Segment 4,009 685 (41 ) 17 2 12 (50 ) - 23 - 4,657
MedTech Fourth QuarterDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Fourth QuarterDec. 29, 2024Non-GAAP
Cost of products sold $ 3,596 (477 ) (20 ) (153 ) (18 ) 2,928
Selling, marketing and admin expenses 2,836 (4 ) 2,832
Research and development expense 1,600 (25 ) 1,575
Other segment items 84 (9 ) 29 (40 ) (115 ) 18 (33 )
Adjusted Income Before Tax by Segment 72 486 (29 ) - 60 268 (18 ) 47 - - 886
Expenses not allocated to segments Fourth QuarterDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Fourth QuarterDec. 29, 2024Non-GAAP
Cost of products sold $ 18 18
Selling, marketing and admin expenses 305 305
Research and development expense - -
Other segment items (129 ) (54 ) (18 ) (201 )
Adjusted Income Before Tax by Segment (194 ) - 54 - - 18 - - - - (122 )
Johnson & Johnson Consolidated Fourth QuarterDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Fourth QuarterDec. 29, 2024Non-GAAP
Cost of products sold $ 7,128 (1,162 ) (20 ) (153 ) (18 ) 5,775
Selling, marketing and admin expenses 6,453 (4 ) 6,449
Research and development expense 5,298 (25 ) (6 ) 5,267
Other (Income) / Expense (161 ) (9 ) 16 (145 ) 68 (17 ) (248 )
In-process research and development impairments 17 (17 ) -
Interest (Income)/Expense (144 ) (144 )
Restructuring 42 (42 ) -
Adjusted Income Before Tax 3,887 1,171 (16 ) 17 62 298 (68 ) 47 23 - 5,421
Provision for taxes on income 456 171 (158 ) 4 3 80 (34 ) 9 5 (61 ) 475
Net Earnings $ 3,431 1,000 142 13 59 218 (34 ) 38 18 61 4,946
Johnson & Johnson and Subsidiaries
GAAP to Non-GAAP Reconciliation
$ in Millions
Year to Date
Innovative Medicine Twelve MonthsDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Twelve MonthsDec. 28, 2025Non-GAAP
Cost of products sold $ 15,646 (2,706 ) (35 ) 12,905
Selling, marketing and admin expenses 11,375 11,375
Research and development expense 11,827 11,827
Other segment items (713 ) 90 (11 ) (327 ) 265 (10 ) (706 )
Adjusted Income Before Tax by Segment 22,266 2,706 (90 ) 11 - 362 (265 ) - - 10 25,000
MedTech Twelve MonthsDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Twelve MonthsDec. 28, 2025Non-GAAP
Cost of products sold $ 14,549 (1,915 ) (91 ) (52 ) 12,491
Selling, marketing and admin expenses 11,354 11,354
Research and development expense 2,838 37 2,875
Other segment items 938 (896 ) (70 ) (421 ) 135 162 (48 ) (10 ) (210 )
Adjusted Income Before Tax by Segment 4,113 1,915 896 70 512 (120 ) (162 ) 48 - 10 7,282
Expenses not allocated to segments Twelve MonthsDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Twelve MonthsDec. 28, 2025Non-GAAP
Cost of products sold $ 61 61
Selling, marketing and admin expenses 947 947
Research and development expense - -
Other segment items (7,210 ) 6,846 (43 ) (407 )
Adjusted Income Before Tax by Segment 6,202 - (6,846 ) - - 43 - - - - (601 )
Johnson & Johnson Consolidated Twelve MonthsDec. 28, 2025GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Orthopaedics Separation Related Tax legislation and other tax related Other Twelve MonthsDec. 28, 2025Non-GAAP
Cost of products sold $ 30,256 (4,621 ) (91 ) (87 ) 25,457
Selling, marketing and admin expenses 23,676 23,676
Research and development expense 14,665 37 14,702
Other (Income) / Expense (7,209 ) 6,040 (193 ) (235 ) 427 (48 ) (20 ) (1,238 )
In-process research and development impairments 81 (81 ) -
Interest (Income)/Expense (85 ) (85 )
Restructuring 228 (228 ) -
Adjusted Income Before Tax 32,581 4,621 (6,040 ) 81 512 285 (427 ) 48 - 20 31,681
Provision for taxes on income 5,777 829 (1,509 ) 18 93 267 (96 ) 11 70 6 5,466
Net Earnings $ 26,804 3,792 (4,531 ) 63 419 18 (331 ) 37 (70 ) 14 26,215
Johnson & Johnson and Subsidiaries
GAAP to Non-GAAP Reconciliation
$ in Millions
Year to Date
Innovative Medicine Twelve MonthsDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Twelve MonthsDec. 29, 2024Non-GAAP
Cost of products sold $ 14,036 (2,772 ) (8 ) 11,256
Selling, marketing and admin expenses 10,906 10,906
Research and development expense 13,529 (25 ) 13,504
Other segment items (426 ) (358 ) (211 ) (102 ) (66 ) 76 (67 ) (1,154 )
Adjusted Income Before Tax by Segment 18,919 2,772 358 211 102 66 (76 ) - 100 - 22,452
MedTech Twelve MonthsDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Twelve MonthsDec. 29, 2024Non-GAAP
Cost of products sold $ 13,345 (1,745 ) (35 ) (359 ) (84 ) 11,122
Selling, marketing and admin expenses 10,812 (16 ) 10,796
Research and development expense 3,703 (69 ) (104 ) 3,530
Other segment items 257 (9 ) 14 (132 ) (587 ) (30 ) (487 )
Adjusted Income Before Tax by Segment 3,740 1,754 (14 ) - 167 1,015 30 204 - - 6,896
Expenses not allocated to segments Twelve MonthsDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Twelve MonthsDec. 29, 2024Non-GAAP
Cost of products sold $ 90 90
Selling, marketing and admin expenses 1,151 1,151
Research and development expense - -
Other segment items 4,731 (5,106 ) (145 ) (352 ) (872 )
Adjusted Income Before Tax by Segment (5,972 ) - 5,106 - - 145 352 - - - (369 )
Johnson & Johnson Consolidated Twelve MonthsDec. 29, 2024GAAP Intangible asset amortization Litigation related In-process research and development impairments Restructuring related Acquisition, integration and divestiture related (Loss)/gain on securities Medical Device Regulation COVID-19 Vaccine Related Costs Tax legislation and other tax related Twelve MonthsDec. 29, 2024Non-GAAP
Cost of products sold $ 27,471 (4,517 ) (35 ) (359 ) (84 ) (8 ) 22,468
Selling, marketing and admin expenses 22,869 (16 ) 22,853
Research and development expense 17,232 (69 ) (104 ) (25 ) 17,034
Other (Income) / Expense 4,694 (9 ) (5,450 ) (798 ) (306 ) (67 ) (1,936 )
In-process research and development impairments 211 (211 ) -
Interest (Income)/Expense (577 ) (577 )
Restructuring 234 (234 ) -
Adjusted Income Before Tax 16,687 4,526 5,450 211 269 1,226 306 204 100 - 28,979
Provision for taxes on income 2,621 644 1,066 47 45 302 (29 ) 38 22 (19 ) 4,737
Net Earnings $ 14,066 3,882 4,384 164 224 924 335 166 78 19 24,242

Frequently Asked Questions

What were Johnson & Johnson's Q4 2025 results?

Johnson & Johnson reported strong financial results for Q4 2025, driven by growth in its Innovative Medicine and MedTech segments.

What factors contributed to JNJ's growth in 2025?

Growth was fueled by a strong portfolio, innovative products, and successful sales in Oncology, Immunology, and Neuroscience.

What challenges did Johnson & Johnson face in 2025?

The company faced challenges such as the impact of STELARA in Immunology and uncertainties in predicting future financial outcomes.

When will JNJ hold its investor conference call?

Johnson & Johnson will conduct a conference call with investors today at 8:30 a.m. Eastern Time.

Last updated: Jan 21, 2026