Full Press Release Details
Receives Additional 180-day Grace Period to Regain Compliance with Nasdaq's Bid Price Rule
San Francisco, CA (November 8, 2023):
Jaguar Health, Inc. (NASDAQ:JAGX) ("Jaguar" or the "Company") today announced that on November 8, 2023 the Company
received formal notice that the Listing Qualifications Staff (the "Staff") of The Nasdaq Stock Market LLC has granted Jaguar
an additional 180-day grace period, through May 6, 2024, to regain compliance with the $1.00 bid price requirement for continued listing
on The Nasdaq Capital Market. The Staff noted that the Company meets all other applicable requirements for initial and continued listing
on The Nasdaq Capital Market. To evidence compliance, the Company must report a closing bid price of at least $1.00 per share for a minimum
of ten consecutive business days on or before May 6, 2024.
"We are pleased to have obtained
additional time from Nasdaq to evidence compliance with the bid price requirement," Lisa Conte, Jaguar's president and CEO, said.
"Our paramount near-term clinical activity is our Phase 3 pivotal OnTarget trial of Mytesi for the follow-on indication of the
preventative treatment of cancer therapy-related diarrhea, an indication we also refer to as chemotherapy-induced overactive bowel (CIOB)
- which includes symptoms such as chronic debilitating diarrhea, GI urgency, and GI incontinence. Top line results from this pivotal
study are expected before Thanksgiving."
Jaguar is supporting investigator-initiated
and investigator IND proof-of-concept studies of crofelemer for the rare disease indications of microvillus inclusion disease (MVID)
and short bowel syndrome (SBS) with intestinal failure in the US, EU and Middle East/North Africa (MENA) regions, with results expected
before the end of 2023 and in 2024. In accordance with the guidelines of specific EU countries, published data from such clinical investigations
could support reimbursed early patient access to crofelemer for SBS or MVID for these debilitating conditions.
Crofelemer has been granted Orphan Drug
Designation (ODD) by the FDA and the European Medicines Agency (EMA) for both MVID and SBS with intestinal failure. The ODD programs
in the U.S. and European Union qualify sponsors to receive potential incentives to develop therapies for the diagnosis, prevention, or
treatment of rare diseases or conditions.
About the Jaguar Health Family of
Jaguar Health, Inc. (Jaguar) is a commercial
stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest
areas for people and animals with gastrointestinal distress, specifically associated with overactive bowel, which includes symptoms such
as chronic debilitating diarrhea, urgency, bowel incontinence, and cramping pain. Jaguar family company Napo Pharmaceuticals focuses
on developing and commercializing human prescription pharmaceuticals for essential supportive care and management of neglected gastrointestinal
symptoms across multiple complicated disease states. Napo Pharmaceuticals' crofelemer drug product candidate is the subject of
the OnTarget study, an ongoing pivotal Phase 3 clinical trial for preventive treatment of chemotherapy-induced overactive bowel (CIOB)
in adults with cancer on targeted therapy. Jaguar family company Napo Therapeutics is an Italian corporation Jaguar established in Milan,
Italy in 2021 focused on expanding crofelemer access in Europe and specifically for orphan and/or rare diseases. Jaguar Animal Health
is a Jaguar tradename. Magdalena Biosciences, a joint venture formed by Jaguar and Filament Health Corp. that emerged from Jaguar's
Entheogen Therapeutics Initiative (ETI), is focused on developing novel prescription medicines derived from plants for mental health
For more information about:
Jaguar Health, visit https://jaguar.health
Napo Pharmaceuticals, visit www.napopharma.com
Napo Therapeutics, visit napotherapeutics.com
Magdalena Biosciences, visit magdalenabiosciences.com
Visit Jaguar on LinkedIn: https://www.linkedin.com/company/jaguar-health/
Visit Jaguar on X: https://twitter.com/Jaguar_Health
Visit Jaguar on Instagram: https://www.instagram.com/jaguarhealthcommunity/
Forward-Looking Statements
Certain statements in this press release
constitute "forward-looking statements." These include statements regarding Jaguar's expectation that top line results
of the OnTarget study will be available before Thanksgiving 2023. In some cases, you can identify forward-looking statements by terms
such as "may," "will," "should," "expect," "plan," "aim," "anticipate,"
"could," "intend," "target," "project," "contemplate," "believe,"
"estimate," "predict," "potential" or "continue" or the negative of these terms or other
similar expressions. The forward-looking statements in this release are only predictions. Jaguar has based these forward-looking statements
largely on its current expectations and projections about future events. These forward-looking statements speak only as of the date of
this release and are subject to a number of risks, uncertainties and assumptions, some of which cannot be predicted or quantified and
some of which are beyond Jaguar's control. Except as required by applicable law, Jaguar does not plan to publicly update or revise
any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or
Source: Jaguar Health, Inc.