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The Jean Perrin Center, with participation from the Toulouse Oncopole and the Bordeaux University Hospital Center, will analyze biopsy samples from patients with advanced colorectal, breast, melanoma or lung cancer using CGP enabled by Illumina's TruSight™ Oncology 500 assay.
"Personalized treatments that target cancer mutations have improved prognosis greatly, helping us direct patients to the best option for them," explained Professor Pascal Pujol , President of the French Society for Predictive and Personalized Medicine, and Head of the Oncogenetics Department at Montpellier University Hospital. "It is critical to ensure that the use of comprehensive analysis based on large DNA and RNA panels becomes part of routine practice so that patients can benefit from the best possible care."
SeqOne Genomics, a French deep tech company offering high performance genomic analysis solutions, has been selected by the three centers for analysis of the data and generation of clinical reports that outline possible treatment options and clinical trial eligibility. Illumina is providing sequencing reagents and biostatistician expertise.
About TruSight Oncology 500 Portfolio
TSO 500 is a Research Use Only pan-cancer assay that enables Comprehensive Genomic Profiling from tissue biopsy samples. Designed to identify known and emerging tumor biomarkers across 523 genes, TSO 500 utilizes both DNA and RNA from tumor samples to identify key variants critical for cancer development and progression, such as small DNA variants, fusions, and splice variants. In addition, the assay assesses key immune-oncology biomarkers, such as Tumor Mutational Burden (TMB) and Microsatellite Instability (MSI). TSO 500 ctDNA shares similar DNA panel content design to the tissue-based assay but utilizes ctDNA from blood as input material. Due to the TSO 500 portfolio's comprehensive biomarker content, labs can consolidate multiple single gene or small panel workflows into a single assay, saving biopsy specimen and time. Based on the content of TSO 500, Illumina will be adding an in vitro diagnostic (IVD) test to the TSO portfolio. This comprehensive tissue-based tumor profiling assay will have similar chemistry and analytics to TSO 500. To learn more about the TSO 500 portfolio, click here.
About Illumina Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. To learn more, visit www.illumina.com and connect with us on Twitter , Facebook , LinkedIn , Instagram , and YouTube .
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SOURCE Illumina, Inc.