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Monte Rosa Therapeutics to Present Updated MRT-2359 Phase 1/2 Study Results

Key Takeaway: Monte Rosa Therapeutics will present updated results from its Phase 1/2 study of MRT-2359, targeting metastatic castration-resistant prostate cancer. The live conference call is scheduled for December 16, 2025, at 8:00 a.m. ET. The presentation will provide interim clinical results from the ongoing study, highlighting the company's advancements in molecular glue degrader medicines.
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Market Sentiment Analysis

POSITIVE FACTORS

  • Monte Rosa Therapeutics is advancing its innovative MGD-based medicines.
  • The interim results from the MRT-2359 study are being presented to stakeholders.
  • The company has a strong pipeline with first-in-class MGDs in various therapeutic areas.

Full Press Release Details

BOSTON, Dec. 15, 2025 (GLOBE NEWSWIRE) --Monte Rosa Therapeutics, Inc.(Nasdaq: GLUE), a clinical-stage biotechnology company developing novel molecular glue degrader (MGD)-based medicines, today announced that management will host a live conference call and webcast on Tuesday, December 16, 2025, at 8:00 a.m. ET. The webcast presentation will highlight interim clinical results from the ongoing Phase 1/2 study of the GSPT1-directed MGD MRT-2359 in heavily pretreated, metastatic castration-resistant prostate cancer (mCRPC) patients.
A webcast of the presentation will be accessible via the “Events & Presentations” section of Monte Rosa’s website atir.monterosatx.com. Registration for the conference call is available at the followinglink. An archived version of the webcast will be made available for 30 days following the presentation.
About Monte RosaMonte Rosa Therapeutics is a clinical-stage biotechnology company developing highly selective molecular glue degrader (MGD) medicines for patients living with serious diseases. MGDs are small molecule protein degraders that have the potential to treat many diseases that other modalities, including other degraders, cannot. Monte Rosa’s QuEEN™ (Quantitative and Engineered Elimination of Neosubstrates) discovery engine combines AI-guided chemistry, diverse chemical libraries, structural biology, and proteomics to rationally design MGDs with unprecedented selectivity. Monte Rosa has developed the industry’s leading pipeline of first-in-class and only-in-class MGDs, spanning autoimmune and inflammatory diseases, oncology, and beyond, with three programs in the clinic. Monte Rosa has ongoing collaborations with leading pharmaceutical companies in the areas of immunology, oncology and neurology. For more information, visitwww.monterosatx.com.

MediaCory Tromblee, Scient PRmedia@monterosatx.com

Frequently Asked Questions

What is the focus of the MRT-2359 study?

The MRT-2359 study focuses on heavily pretreated metastatic castration-resistant prostate cancer patients.

When will the conference call take place?

The conference call is scheduled for December 16, 2025, at 8:00 a.m. ET.

How can I access the webcast of the presentation?

The webcast can be accessed via the 'Events & Presentations' section of Monte Rosa's website.

What type of medicines is Monte Rosa developing?

Monte Rosa is developing novel molecular glue degrader-based medicines for serious diseases.

Last updated: Dec 15, 2025