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BriaCell Awarded National Cancer Institute Grant to Advance its Bria-OTS™ Immunotherapy for Cancer

Key Takeaway: BriaCell Therapeutics Corp. has been awarded a grant by the National Cancer Institute (NCI) to advance its Bria-OTS™ immunotherapy platform for treating advanced cancers, including breast, prostate, lung, and melanoma types. The grant is non-dilutive, helping to validate BriaCell's approach to personalized off-the-shelf therapies while potentially opening doors for future funding. The CEO emphasized the urgent need for effective cancer treatments and expressed gratitude towards the NCI. The development aims to address common issues in personalized cancer treatments such as manufacturing complexity and cost.

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POSITIVE FACTORS

  • BriaCell awarded a non-dilutive grant from the NCI, validating their approach.
  • The funding will support the development of innovative immunotherapy for serious cancers.
  • Promising clinical findings suggest potential for improved patient survival and quality of life.

Full Press Release Details

NCI award (non-dilutive grant) further validates novel personalized off-the-shelf immunotherapy approach; and may facilitate future non-dilutive funding opportunities
PHILADELPHIA and VANCOUVER, British Columbia, Aug. 16, 2023 (GLOBE NEWSWIRE) --  BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) (TSX: BCT) (“BriaCell” or the “Company”), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, is pleased to announce that the National Cancer Institute (NCI), the United States federal government's principal agency for cancer research and training, has awarded the Company a research grant to advance its platform of personalized off-the-shelf immunotherapies for cancer.
The grant award of non-dilutive funds is titled “An off-the-shelf tumor cell vaccine with HLA-matching alleles for the personalized treatment of advanced solid tumors”. The Company intends to use the funds for the development of Bria-OTS™, BriaCell’s novel personalized off-the-shelf immunotherapies for advanced metastatic breast cancer, prostate cancer, lung cancer, and melanoma.
“There is an urgent need for breakthrough cancer treatments that would improve both survival and quality of life of cancer patients, especially in those with advanced disease. Our clinical findings to date show promising top-line survival and quality of life outcomes in patients treated with our personalized immunotherapy,” stated Dr. William V. Williams, BriaCell’s President and CEO. “We would like to thank NCI for its generous support, recognizing the urgency for this unmet medical need, and considering our novel technology, among numerous other applicants, as a treatment that could potentially revolutionize cancer care. The NCI award further validates our approach and may facilitate future non-dilutive funding opportunities.”
“Historically, the manufacturing and administration of personalized cancer treatments have been very time-consuming, complicated, and costly,” stated Dr. Miguel Lopez-Lago, BriaCell’s Chief Scientific Officer. “Our cutting-edge off-the-shelf personalized immunotherapies have the potential to address all these issues and may represent a major advancement in cancer care.”
About BriaCell Therapeutics Corp.
BriaCell is a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care. More information is available at https://briacell.com/.
This press release contains “forward-looking statements” that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “aim,” “should,” “will,” “would,” or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements, including in relation to (i) intends to use the funds for the development of Bria-OTS™; (ii) the results of any research and development of Bria-OTS™; (iii) ability to obtain future non-dilutive funding; and (iv) the ability to address issues relating to manufacturing and administration of personalized cancer treatments, are based on BriaCell’s current expectations and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. These and other risks and uncertainties are described more fully under the heading “Risks and Uncertainties” in the Company's most recent Management’s Discussion and Analysis, under the heading "Risk Factors" in the Company's most recent Annual Information Form, and under “Risks and Uncertainties” in the Company's other filings with the Canadian securities regulatory authorities and the U.S. Securities and Exchange Commission, all of which are available under the Company's profiles on SEDAR at www.sedar.com and on EDGAR at www.sec.gov. Forward-looking statements contained in this announcement are made as of this date, and BriaCell Therapeutics Corp. undertakes no duty to update such information except as required under applicable law.
Neither the Toronto Stock Exchange nor its Regulation Services Provider (as that term is defined in the policies of the Toronto Stock Exchange) accepts responsibility for the adequacy or accuracy of this release.
William V. Williams, MD
Director of Public Relations
Investor Relations Contact:

Frequently Asked Questions

What grant did BriaCell receive from NCI?

BriaCell was awarded a research grant from the NCI to advance personalized off-the-shelf immunotherapies.

How will BriaCell use the NCI grant funds?

The funds will support the development of Bria-OTS™, targeting advanced breast, prostate, lung cancers, and melanoma.

What does Bria-OTS™ aim to address?

Bria-OTS™ aims to provide breakthrough, customizable treatments for advanced cancer patients.

Why is the NCI award important for BriaCell?

The NCI award validates BriaCell's approach and may lead to future funding opportunities.

What is the goal of BriaCell's immunotherapy?

The goal is to improve survival and quality of life for patients with advanced cancer.

Last updated: Aug 16, 2023