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BriaCell Receives and Executes Letter of Intent to Advance Clinical Development of Breast and Prostate Cancer Immunotherapies

Key Takeaway: BriaCell Therapeutics Corp. has signed a letter of intent with Dr. Paula Pohlmann to advance the clinical development of its personalized cancer vaccines, Bria-OTS+ for breast cancer and Bria-PROS+ for prostate cancer. This agreement is seen as a major milestone for the company, aimed at enhancing treatment options for patients with advanced cancer. BriaCell's leadership is optimistic about the potential impact of these therapies on patient survival and quality of life.

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POSITIVE FACTORS

  • BriaCell has executed a significant agreement to advance cancer therapies.
  • The collaboration aims to improve treatment for patients with unmet medical needs.
  • The company expresses strong confidence in its novel vaccine platform.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+44%
120-day peak, hindsight
Typical move
14.8%
average across 8 past catalysts
Cash runway
~7 mo
Medium dilution risk
Lead asset
SV-BR-1-GM
Phase 3 · Breast Cancer

Full Press Release Details

• Agreement with a leading cancer treatment group to advance the clinical development of Bria-OTS+ (breast cancer) and Bria-PROS+ (prostate cancer), BriaCell’s novel off-the-shelf personalized cancer vaccines, marks a major milestone for BriaCell
PHILADELPHIA and VANCOUVER, British Columbia, March 07, 2024 (GLOBE NEWSWIRE) — BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) (TSX: BCT) (“BriaCell” or the “Company”), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, announces that it has received and executed a letter of intent with Paula Pohlmann, MD, MSc, PhD, Associate Professor, Department of Investigational Cancer Therapeutics and Breast Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX to advance the clinical development of Bria-OTS+ and Bria-PROS+, BriaCell’s personalized off-the-shelf cellular cancer vaccines in advanced breast cancer and prostate cancer, respectively.
“We are ecstatic about working with the team led by Dr. Pohlmann,” stated Dr. Williams, BriaCell’s President & CEO. “We strongly believe in the therapeutic potential of our novel personalized next-generation vaccine platform and this agreement will be invaluable to us as we advance the clinical development of our off-the-shelf therapies to those cancer patients with persistent unmet medical needs.”
“Through this agreement, we expect to further our understanding of our novel immunotherapy’s mechanism of action and its use in breast and prostate cancer patients,” stated Dr. Giuseppe Del Priore, BriaCell’s CMO. “Our shared goal is to improve the survival and quality of life in cancer patients who are fighting a disease with a poor prognosis and a short life expectancy.”
About BriaCell Therapeutics Corp.
BriaCell is a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care. More information is available at https://briacell.com/ .
Safe Harbor
This press release contains “forward-looking statements” that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “aim,” “should,” “will,” “would,” or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements, including those in relation to: whether the agreement with Dr. Pohlmann will advance the clinical development of Bria-OTS+ and Bria-PROS+, BriaCell’s personalized off-the-shelf cellular cancer vaccines in advanced breast cancer and prostate cancer, respectively; whether the agreement will be invaluable to BriaCell as it advances the clinical development of its off-the-shelf therapies to those cancer patients with persistent unmet medical needs; and whether the agreement will further BriaCell’s understanding of its novel immunotherapy’s mechanism of action and its use in breast and prostate cancer patients; are based on BriaCell’s current expectations and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. These and other risks and uncertainties are described more fully under the heading “Risks and Uncertainties” in the Company’s most recent Management’s Discussion and Analysis, under the heading “Risk Factors” in the Company’s most recent Annual Information Form, and under “Risks and Uncertainties” in the Company’s other filings with the Canadian securities regulatory authorities and the U.S. Securities and Exchange Commission, all of which are available under the Company’s profiles on SEDAR+ at www.sedarplus.ca and on EDGAR at www.sec.gov . Forward-looking statements contained in this announcement are made as of this date, and BriaCell Therapeutics Corp. undertakes no duty to update such information except as required under applicable law.
Neither the Toronto Stock Exchange nor its Regulation Services Provider (as that term is defined in the policies of the Toronto Stock Exchange) accepts responsibility for the adequacy or accuracy of this release.
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Frequently Asked Questions

What is the purpose of BriaCell's new agreement?

The agreement aims to advance the clinical development of Bria-OTS+ and Bria-PROS+, personalized cancer vaccines for breast and prostate cancer.

Who is BriaCell collaborating with?

BriaCell is collaborating with Dr. Paula Pohlmann from The University of Texas MD Anderson Cancer Center.

What are Bria-OTS+ and Bria-PROS+?

Bria-OTS+ and Bria-PROS+ are off-the-shelf personalized cellular cancer vaccines targeting advanced breast and prostate cancer.

What is BriaCell's goal with this agreement?

BriaCell aims to improve survival and quality of life for cancer patients with poor prognosis through this collaboration.

Last updated: Mar 7, 2024