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Zymeworks Inc.

$25.88

-0.7 (-2.59%)

C 44Pipeline Score Fair Value Pharma · Commercial
Market Cap
1.88 B
EPS
-1.37
P/E Ratio
-
Value Trade
19.47 M
SEC Financials
Q1 2026
  • Dilution Risk

    5%
  • Revenue

    2.41 M

  • R&D Expenses

    34.46 M

  • Operating CF

    -45.72 M


  • Total Assets

    478.21 M

  • Total Liabilities

    314.63 M

  • Equity

    163.59 M

  • D/E Ratio

    12,345

4.53 %
Week
-9.82 %
1 Month
10.58 %
3 Month
7.51 %
6 Month
-14.43 %
5 Year
89.7 %
All Time
Cash Data
Healthy
  • Cash Position

    403.84 M

  • Monthly Burn

    15.24 M

  • Runway

    24.6 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 7, 2026
Overview
Volume
483.25 K
52 Week Range
11.02 - 29.75
% held by Insiders
4.3 %
% held by Institutions
98.94 %
Enterprise Value
1.78 B
Total Shares
73.77 M
Short %
9.5 %
Float Shares
45.96 M
Company Description
HQ: 108 PATRIOT DRIVE, SUITE A, MI...
Employees:264

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
Ziihera (zanidatamab-hrii) first-line HER2-positive unresectable locally advanced or metastatic gastroesophageal adenocarcinoma (GEA)
BreakthroughPriorityAccelerated
PDUFA

Subscribe to access the data.

Antibody-Drug Conjugates (ADCs)
Oncology
Ziihera (zanidatamab-hrii) first-line HER2-positive unresectable locally advanced or metastatic gastroesophageal adenocarcinoma (GEA)
BreakthroughPriorityAccelerated
PDUFA

Subscribe to access the data.

Antibody-Drug Conjugates (ADCs)
Oncology
Ziihera (zanidatamab-hrii) first-line HER2-positive unresectable locally advanced or metastatic gastroesophageal adenocarcinoma (GEA)
BreakthroughPriorityAccelerated
PDUFA

Subscribe to access the data.

Antibody-Drug Conjugates (ADCs)
Oncology
Unlock Upcoming Catalyst data

Catalyst Timeline

Dated clinical, regulatory & corporate events for Zymeworks Inc.

264Total events
15Upcoming
73Tier-1 (high impact)
2022 – 2027Coverage

Upcoming catalysts 15

Aug 25, 2026
T1PDUFA Date
PDUFA target action date of August 25, 2026 for zanidatamab sBLA
ZanidatamabApprovedfirst-line HER2-positive unresectable locally advanced or metastatic gastroesophageal adenocarcinoma
Dec 2026
T2Runway Guidance Update
Cash resources expected to fund operations through at least end of 2026
2027
T2Enrollment Complete
Jazz expects to complete enrollment in 1H 2027
ZanidatamabApprovedmetastatic HER2+ breast cancerPhase 3
2027
T1Topline Readout
Top-line data readout for EmpowHER-303 expected later in 2027 or early 2028
ZanidatamabApprovedmetastatic HER2+ breast cancerPhase 3
2027
T2Enrollment Complete
Jazz expects to complete enrollment in EmpowHER-303 in 1H 2027
ZanidatamabApprovedmetastatic HER2+ breast cancerPhase 3
2027
T1Topline Readout
Topline data readout for EmpowHER-303 expected later in 2027 or early 2028
ZanidatamabApprovedmetastatic HER2+ breast cancerPhase 3
2027
T2Pipeline Prioritization
Progress product candidates from ADVANCE R&D programs into clinical studies by 2027 and beyond
2027
T2Trial Initiation
Advance at least five novel medicines into clinical studies by 2027
Q1 2027
T2Milestone Payment
Expected $100 million milestone payment from Royalty Pharma related to TRELEGY ELLIPTA global net sales
COPD
TBD
T1Full Results
Data from Part 2a to be presented at a future medical meeting to inform dose selection
ZW191platinum-resistant ovarian cancerPhase 1
TBD
T2Milestone Payment
Anticipated $440M in regulatory milestone payments for Ziihera approvals in US, EU, Japan, China
Ziiheragastroesophageal adenocarcinoma
TBD
T2Milestone Payment
Potential near-term milestone payments for Ziihera regulatory approvals in GEA totaling $440M
ZanidatamabApprovedgastroesophageal adenocarcinoma
TBD
T2Publication
Publication in peer-reviewed journal planned
ZanidatamabApprovedHER2-positive locally advanced or metastatic gastroesophageal adenocarcinomaPhase 3
TBD
T2Trial Initiation
Phase 1 study for ZW191 actively recruiting
ZW191Phase 1
TBD
T2Milestone Payment
Up to $18M development and $186.5M commercial milestones for pasritamig
Pasritamig

Event history 249

Jun 29, 2026
Quarterly UpdateCorporate
Investor conference call to discuss acquisition
Jun 18, 2026
Partnership / LicenseCorporate
Partnership with Gandeeva to use cryo-EM for antibody drug discovery
Jun 14, 2026
Oral PresentationZW191Presentation
Presented new Phase 1 data for ZW191 at ESMO Gynaecological Cancers Congress 2026
platinum-resistant ovarian cancer, endometrial cancersource ↗
Jun 14, 2026
Enrollment CompleteZW191Trial
Completed enrollment in Part 2a dose optimization cohort (~60 PROC patients randomized to 6.4 or 9.6 mg/kg Q3W)
platinum-resistant ovarian cancersource ↗
Jun 2026
Oral PresentationZanidatamabApprovedPresentation
Jazz to present PD-L1 subgroup data from HERIZON-GEA-01 at ASCO
first-line HER2-positive GEAsource ↗
Jun 2026
Interim AnalysisZanidatamabApprovedTrial
Second interim overall survival analysis for HERIZON-GEA-01 expected mid-2026
first-line HER2-positive GEAsource ↗
Jun 2026
IND SubmissionIND
Planned IND filing for fifth candidate in 1H 2026
May 14, 2026
ATM ProgramCorporate
Board authorizes 2026 share repurchase program of up to $125 million
May 14, 2026
Equity OfferingCorporate
Share repurchase program authorized up to $125 million
May 13, 2026
R&D DayPresentation
Management to participate in upcoming investor conferences
May 7, 2026
Quarterly UpdateCorporate
Reported Q1 2026 financial results; cash $403.8M
May 7, 2026
Runway Guidance UpdateCorporate
Expect cash resources to fund operations beyond 2028, including anticipated milestone payments
Drug Pipeline Intelligence
C44
Pipeline Score
$497M
Pipeline Value
Fair Value
Valuation Signal
6
Drugs Scored
0.9x
rNPV / MCap
Top 63%
Micro Cap
(rank 338 of 911)
Percentile Rank
Zymeworks Inc. carries a moderate pipeline score (44/100), with $1.2B risk-adjusted pipeline value, led by Futibatinib in Biliary Tract Neoplasms (Phase 3).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
Futibatinib
Small molecule
Biliary Tract NeoplasmsPhase 3NCT0561581842% $871M RECRUITING 800 - -Jun 1, 2028MODERATE_RISKLOW
May 26, 2026
Unlock Drug Pipeline Intelligence
Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
ZW191
Fast Track
platinum-resistant ovarian cancer and endometrial cancer
Phase 1
2026-06-14

c ORR FRα positive: 78.6%; c ORR FRα negative: 47.4%; overall c ORR: 58.8%; c ORR dose range: 65.2%; c ORR endometrial FRα negative: 40.0%; disease control rate FRα positive: 100.0%; disease control rate FRα negative: 89.5%; median progression free survival: 7.6 months

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Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

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ZW191
Fast Track
platinum-resistant ovarian cancer and endometrial cancer
Phase 1
2026-06-14

c ORR FRα positive: 78.6%; c ORR FRα negative: 47.4%; overall c ORR: 58.8%; c ORR dose range: 65.2%; c ORR endometrial FRα negative: 40.0%; disease control rate FRα positive: 100.0%; disease control rate FRα negative: 89.5%; median progression free survival: 7.6 months

Read More

Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

Read More
ZW191
Fast Track
platinum-resistant ovarian cancer and endometrial cancer
Phase 1
2026-06-14

c ORR FRα positive: 78.6%; c ORR FRα negative: 47.4%; overall c ORR: 58.8%; c ORR dose range: 65.2%; c ORR endometrial FRα negative: 40.0%; disease control rate FRα positive: 100.0%; disease control rate FRα negative: 89.5%; median progression free survival: 7.6 months

Read More

Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

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Unlock Clinical Trial Results data
Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
ZYME Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
2026-08-21 0.00 0 - - - - - -
2026-08-21 0.00 0 - - - - - -
2026-08-21 0.00 0 - - - - - -
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
Unlock Option Chain data
Unlock Options Chart data
Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
ZYME
Jun 29, 2026
ZYMEGeneral

Zymeworks to Acquire Theravance Biopharma, Inc.

Zymeworks has announced its acquisition of Theravance Biopharma for $17 per share, totaling approximately $929 million. This acquisition includes YUPELRI®, the only approved nebulized LAMA for COPD, which is expected to enhance Zymeworks' portfolio and generate significant cash flow. The deal is supported by a non-recourse financing structure, minimizing capital risk and is anticipated to close in the second half of 2026.

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ZYME
Jun 18, 2026
ZYMEGeneral

Gandeeva and Zymeworks Use Cryo-EM to Accelerate Antibody Drug Discovery

Gandeeva Therapeutics and Zymeworks have formed a partnership to utilize cryo-electron microscopy (cryo-EM) for antibody drug discovery. This collaboration aims to visualize antibody-antigen interfaces at high resolution, particularly focusing on small and flexible antigens. The ability to obtain near-atomic resolution structures is expected to significantly enhance the selection and optimization of antibody leads.

Read more →
ZYME
Jun 14, 2026
ZYMEPhases

Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

Zymeworks presented promising Phase 1 data for ZW191, an antibody-drug conjugate targeting folate receptor alpha, at the ESMO Gynaecological Cancers Congress 2026. The data revealed a confirmed objective response rate of 78.6% in FRα-positive ovarian cancer patients and 47.4% in FRα-negative patients. The therapy exhibited a favorable safety profile, with manageable adverse events, supporting its continued clinical development.

Read more →
ZYME
May 27, 2026
ZYMEPhases

BeOne Medicines Announces Phase 3 HERIZON-GEA Data Published in NEJM and Presented at ASCO 2026

BeOne Medicines Announces Phase 3 HERIZON-GEA Data Published in NEJM and Presented at ASCO 2026

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ZYME
May 27, 2026
ZYMEPhases

Phase 3 HERIZON-GEA-01 Results Published in The New England Journal of Medicine Show Durable and Consistent Survival Benefit with Ziihera® (zanidatamab-hrii) Combinations in First-Line HER2+ Locally Advanced or Metastatic GEA

Phase 3 HERIZON-GEA-01 Results Published in The New England Journal of Medicine Show Durable and Consistent Survival Benefit with Ziihera® (zanidatamab-hrii) Combinations in First-Line HER2+ Locally Advanced or Metastatic GEA

Read more →
ZYME
May 14, 2026
ZYMEGeneral

Zymeworks Announces Share Repurchase Program of up to $125 Million of its Common Stock Vancouver, British Columbia (

Zymeworks Inc. has announced a share repurchase program allowing for the repurchase of up to $125 million of its common stock. This decision is part of a strategic initiative to enhance capital allocation and provide returns to shareholders, while also preserving financial flexibility to invest in research and development projects. The company has terminated its previous repurchase program from 2025, having bought back over 4 million shares. The new program demonstrates Zymeworks' focus on long-term value creation.

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ZYME
May 13, 2026
ZYMEConferences/Events

Zymeworks Announces Participation in Upcoming Investor Conferences - May 13, 2026

Zymeworks Inc. announced its participation in upcoming investor conferences, highlighting its commitment to engaging with the investment community. The company is focused on managing a portfolio of licensed healthcare assets and developing innovative biotherapeutics targeting difficult-to-treat diseases. Zymeworks continues to advance its pipeline, leveraging proprietary technology and strategic partnerships.

Read more →
ZYME
May 8, 2026
ZYMEConferences/Events
▼ -10.2%on this newsshared move

Zymeworks to Present at Respiratory Innovation Summit

Zymeworks to Present at Respiratory Innovation Summit

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ZYME
May 7, 2026
ZYMEFDA Updates

Document Zymeworks Provides Corporate Update and Reports First Quarter 2026 Financial Results Jazz announced U.S. FDA acceptance with Priority Review of Supplemental Biologics License Application (sBLA) for zanidatamab i

Zymeworks Inc. reported its financial results for Q1 2026, highlighting significant regulatory achievements for zanidatamab, which has a PDUFA date set for August 25, 2026. The company also shared promising clinical data for ZW191, showing a 56% objective response rate in ovarian cancer patients. Zymeworks is financially robust, with $403.8 million in cash and equivalents. Additionally, changes to the leadership team were announced to improve strategic execution.

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ZYME
May 7, 2026
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports First Quarter 2026 Financial Results

Zymeworks Provides Corporate Update and Reports First Quarter 2026 Financial Results

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ZYME
Apr 29, 2026
ZYMEFDA Updates

U.S. FDA Grants Priority Review to BeOne Medicines’ TEVIMBRA in First-Line HER2+ GEA

U.S. FDA Grants Priority Review to BeOne Medicines’ TEVIMBRA in First-Line HER2+ GEA

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ZYME
Apr 27, 2026
ZYMEFDA Updates

Jazz Pharmaceuticals Announces FDA Acceptance and Priority Review of Supplemental Biologics License Application for Ziihera® (zanidatamab-hrii) Combinations in First-Line HER2+ Locally Advanced or Metastatic GEA

Jazz Pharmaceuticals Announces FDA Acceptance and Priority Review of Supplemental Biologics License Application for Ziihera® (zanidatamab-hrii) Combinations in First-Line HER2+ Locally Advanced or Metastatic GEA

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ZYME
Apr 21, 2026
ZYMEPhases

Zymeworks Presents New Phase 1 Data for ZW191, a Folate Receptor Alpha-Targeting ADC at AACR Annual Meeting 2026

Zymeworks presented promising Phase 1 data for ZW191, an ADC targeting folate receptor alpha, at the AACR Annual Meeting 2026. The therapy showed a 61% confirmed objective response rate in platinum-resistant ovarian cancer and demonstrated manageable safety. The study supports further development of ZW191 for patients with limited treatment options in ovarian and endometrial cancers.

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ZYME
Apr 17, 2026
ZYMEPhases

Zymeworks Presents New Preclinical Data at AACR 2026 Highlighting Broad Antibody-Drug Conjugate Programs Including Novel RAS-Targeting Platform

Zymeworks Presents New Preclinical Data at AACR 2026 Highlighting Broad Antibody-Drug Conjugate Programs Including Novel RAS-Targeting Platform

Read more →
ZYME
Apr 16, 2026
ZYMEConferences/Events

Zymeworks to Report First Quarter 2026 Financial Results and Host Conference Call on May 7, 2026

Zymeworks Inc. will report its first quarter 2026 financial results on May 7, 2026, after market close. A conference call and webcast will follow at 4:30 PM ET to discuss the results and provide a corporate update. The event will be accessible via Zymeworks' website.

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ZYME
Apr 9, 2026
ZYMEGeneral

Zymeworks Announces Additional Leadership Appointments to Advance Next Phase of Growth

Zymeworks Announces Additional Leadership Appointments to Advance Next Phase of Growth

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ZYME
Apr 9, 2026
ZYMEConferences/Events

Zymeworks to Present at the AACR Oncology Industry Partnering Event

Zymeworks to Present at the AACR Oncology Industry Partnering Event

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ZYME
Apr 1, 2026
ZYMEGeneral

Zymeworks Appoints Kristin Stafford as Chief Financial Officer

Zymeworks Inc. has appointed Kristin Stafford as Chief Financial Officer, effective April 1, 2026. Stafford brings significant experience from her previous roles, including at Royalty Pharma and Ernst & Young. Her expertise is expected to contribute to Zymeworks' strategic goals and operational excellence as the company advances its biotherapeutics pipeline.

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ZYME
Mar 30, 2026
ZYMEFDA Updates

Zymeworks Receives U.S. FDA Fast Track Designation for ZW191, an FRα-Targeting Antibody-Drug Conjugate

Zymeworks has been granted Fast Track designation by the FDA for ZW191, an antibody-drug conjugate targeting folate receptor-α, aimed at treating advanced or metastatic platinum-resistant ovarian cancer. The ongoing Phase 1 clinical trial is assessing the drug's safety and preliminary anti-tumor activity. This designation underscores Zymeworks' commitment to addressing significant unmet medical needs in oncology.

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ZYME
Mar 24, 2026
ZYMEConferences/Events

Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. has announced its participation in two upcoming investor conferences. The management will engage in virtual meetings and present at the Needham 25th Annual Virtual Healthcare Conference on April 15, followed by the 2026 Bloom Burton & Co. Healthcare Investor Conference in Toronto on April 21. This participation highlights Zymeworks' commitment to investor engagement and its ongoing development of innovative biotherapeutics.

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ZYME
Mar 18, 2026
ZYMEConferences/Events

Zymeworks Announces Presentations for Ziihera® (zanidatamab-hrii) at 2026 AACR Annual Meeting

Zymeworks Announces Presentations for Ziihera® (zanidatamab-hrii) at 2026 AACR Annual Meeting

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ZYME
Mar 17, 2026
ZYMEConferences/Events

Zymeworks to Present Clinical and Preclinical Data on ADC Programs Including Novel RAS ADC Platform at AACR Annual Meeting

Zymeworks announced the presentation of new clinical and preclinical data at the AACR Annual Meeting, showcasing their ADC programs, including ZW191, which targets folate receptor alpha. The data highlights ZW191's potential effectiveness in advanced solid tumors and the promising activity of new ADC candidates against RAS-mutated cancers. The presentations will occur between April 17-22, 2026, in San Diego, CA.

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ZYME
Mar 2, 2026
ZYMEGeneral

Zymeworks and Royalty Pharma Enter into $250 Million Royalty-Backed Note Financing

Zymeworks has entered into a $250 million royalty-backed note financing agreement with Royalty Pharma. The deal allows Zymeworks to receive 30% of worldwide tiered royalties on Ziihera sales, while retaining 70% of the royalties during the repayment period. This funding is aimed at strengthening Zymeworks' balance sheet and supporting its strategic initiatives, including stock repurchases and potential acquisitions.

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ZYME
Mar 2, 2026
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2025 Financial Results

Zymeworks Inc. provided a corporate update alongside its financial results for 2025, reporting a 39% increase in total revenue to $106 million. The company highlighted significant milestones for its HER2-targeted therapy, Ziihera, and announced a $250 million royalty-backed financing arrangement with Royalty Pharma. Despite a net loss of $81.1 million, Zymeworks maintains a strong cash position and is focused on executing its strategic priorities in 2026.

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ZYME
Mar 2, 2026
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2025 Financial Results Supplemental Biologics License Application for Ziihera (zanidatamab-hrii) to be completed by our partner Jazz i

Zymeworks has released its fourth quarter and full year 2025 financial results, reporting a revenue increase of 39% and a 34% reduction in net loss compared to 2024. The company is preparing to submit a Supplemental Biologics License Application for its drug Ziihera in HER2-positive gastroesophageal adenocarcinoma, with a projected launch between late 2026 and early 2027. Additionally, Zymeworks highlighted its innovative financing strategy through a $250 million royalty-backed note, which is intended to support its ongoing share repurchase program and future acquisitions.

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ZYME
Feb 12, 2026
ZYMEConferences/Events

Zymeworks To Report Fourth Quarter and Full Year 2025 Financial Results and Host Conference Call on March 2, 2026

Zymeworks Inc. will report its fourth quarter and full year 2025 financial results on March 2, 2026. A conference call and webcast will follow the announcement at 8:30 am ET to discuss the results and provide a corporate update. The company is known for its innovative biotherapeutics aimed at challenging diseases.

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ZYME
Jan 12, 2026
ZYMEGeneral

Zymeworks Announces Leadership Appointments and Transitions to Align with Evolution of Corporate Strategy

Zymeworks Announces Leadership Appointments and Transitions to Align with Evolution of Corporate Strategy

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ZYME
Jan 11, 2026
ZYMEGeneral

Zymeworks Outlines Strategic Priorities and Outlook for 2026

Zymeworks Outlines Strategic Priorities and Outlook for 2026

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ZYME
Jan 6, 2026
ZYMEGeneral
▼ -5.1%on this news

Ziihera® (zanidatamab-hrii) Combinations Achieve Unprecedented Results in First-Line HER2+ Locally Advanced or Metastatic GEA including more than Two Years Median Overall Survival Benefit

Ziihera® (zanidatamab-hrii) Combinations Achieve Unprecedented Results in First-Line HER2+ Locally Advanced or Metastatic GEA including more than Two Years Median Overall Survival Benefit

Read more →
ZYME
Dec 31, 2025
ZYMEGeneral

Zymeworks Outlines Strategic Priorities and Outlook for 2026 Positive Phase 3 HERIZON-GEA-01 results for Ziihera (zanidatamab-hrii) in first-line HER2-positive (HER2+) gastroesophageal adenocarcinoma (GEA) presented at A

Zymeworks has outlined its strategic priorities for 2026 following a transformative year in 2025. The company reported substantial advancements in its clinical programs, especially for its pipeline assets, Ziihera and pasritamig. With a strong financial foundation, Zymeworks plans to leverage revenues from partnered programs while pursuing strategic acquisitions. Moreover, the firm has authorized a $125 million share repurchase program to bolster shareholder value amidst a broader focus on sustainable growth and disciplined capital allocation.

Read more →
ZYME
Dec 2, 2025
ZYMEConferences/Events

Zymeworks Announces Participation in Upcoming Conferences

Zymeworks Announces Participation in Upcoming Conferences

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ZYME
Nov 18, 2025
ZYMEGeneral

Zymeworks Announces Strategic Initiative to Optimize Value of Licensed Products by Building a Diversified Portfolio of Revenue-Generating Assets Strategy will combine internal innovation, licensing, and strategic acquisi

Zymeworks Inc. has unveiled a strategic initiative to enhance revenue from its licensed products, focusing on building a diversified portfolio. This strategy hinges on leveraging expected cash flows from upcoming regulatory approvals for Ziihera and pasritamig. The company anticipates significant milestone payments and royalty revenues, positioning itself as a royalty-driven organization. Zymeworks aims to reinvest proceeds from product commercialization while maintaining a focus on internal R&D and strategic partnerships.

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ZYME
Nov 18, 2025
ZYMEGeneral

Zymeworks Appoints Scott Platshon as Acting Chief Investment Officer

Zymeworks Appoints Scott Platshon as Acting Chief Investment Officer

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ZYME
Nov 17, 2025
ZYMEPhases
▲ +29%on this newsshared move

Zymeworks Announces Positive HERIZON-GEA-01 Phase 3 Results Supporting Ziihera (zanidatamab-hrii) as HER2-Targeted Agent-of-Choice and New Standard of Care in First-Line HER2-Positive Locally Advanced or Metastatic Gastr

Zymeworks announced positive topline results from the Phase 3 HERIZON-GEA-01 trial, demonstrating that Ziihera (zanidatamab-hrii), in combination with chemotherapy and possibly the PD-1 inhibitor Tevimbra, is effective for first-line treatment of HER2-positive gastroesophageal adenocarcinoma. The drug's safety profile aligns with previous results, indicating no new risks. Expectations are set for Jazz Pharmaceuticals to present the findings at a medical meeting and seek adoption into NCCN Guidelines. Zymeworks looks to expand Ziihera's regulatory approval as a leading therapy for this indication.

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ZYME
Nov 6, 2025
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results

Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results

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ZYME
Nov 4, 2025
ZYMEPhases

Zymeworks Presents New Preclinical Data at the Society for Immunotherapy of Cancer Conference

Zymeworks Presents New Preclinical Data at the Society for Immunotherapy of Cancer Conference

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ZYME
Nov 4, 2025
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results Encouraging Phase 1 data on ZW191, an antibody-drug conjugate (ADC) targeting folate receptor- (FR ), presented at the AACR-NC

Zymeworks Inc. reported its financial results for Q3 2025 and provided an update on its clinical programs. The company showcased promising Phase 1 data for its antibody-drug conjugate ZW191, achieving a 53% overall objective response rate. Additionally, the first patient has been dosed in the Phase 1 trial of ZW251 for hepatocellular carcinoma. Zymeworks also achieved a significant milestone payment of $25 million from Johnson & Johnson, while highlighting a cash runway projected into the second half of 2027.

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ZYME
Oct 23, 2025
ZYMEPhases

Zymeworks Presents Initial Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺ at AACR-NCI-EORTC Conference

Zymeworks Presents Initial Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺ at AACR-NCI-EORTC Conference

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ZYME
Oct 16, 2025
ZYMEConferences/Events

Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025

Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025

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ZYME
Oct 13, 2025
ZYMEPhases

Zymeworks to Present Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺, at AACR-NCI-EORTC International Conference

Zymeworks to Present Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺, at AACR-NCI-EORTC International Conference

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ZYME
Oct 9, 2025
ZYMEGeneral

Zymeworks Appoints Dr. Adam Schayowitz as Acting Chief Development Officer

Zymeworks Appoints Dr. Adam Schayowitz as Acting Chief Development Officer

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ZYME
Oct 7, 2025
ZYMEConferences/Events

Zymeworks Announces Upcoming Scientific Presentations at the Society for Immunotherapy of Cancer Annual Meeting

Zymeworks Announces Upcoming Scientific Presentations at the Society for Immunotherapy of Cancer Annual Meeting

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ZYME
Sep 26, 2025
ZYMEPhases

Zymeworks Presents Preclinical Data on ZW1528 at the European Respiratory Society Annual Congress

Zymeworks Presents Preclinical Data on ZW1528 at the European Respiratory Society Annual Congress

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ZYME
Sep 15, 2025
ZYMEConferences/Events

Zymeworks Announces Presentation at the European Respiratory Society (ERS) Congress 2025

Zymeworks Announces Presentation at the European Respiratory Society (ERS) Congress 2025

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ZYME
Sep 2, 2025
ZYMEPhases
▼ -5.4%on this news

Zymeworks Announces Decision to Discontinue Clinical Development of ZW171, a Mesothelin-directed T cell Engager Vancouver, British Columbia (

Zymeworks Inc. has announced the voluntary discontinuation of the clinical development of ZW171, a mesothelin-directed T cell engager. The decision follows the completion of planned dose escalation trials, where it was determined that the therapy's benefit-risk profile was not in line with expectations. While this outcome is disappointing, Zymeworks emphasizes its commitment to advancing other candidates in its pipeline, including ongoing trials for ZW191 and ZW251. The company remains focused on its broader goals despite this setback.

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ZYME
Aug 11, 2025
ZYMEGeneral

Zymeworks Strengthens Board of Directors with Appointments of Greg Ciongoli and Robert E. Landry Vancouver, British Columbia (

Zymeworks Inc. has announced the appointments of Greg Ciongoli and Robert E. Landry to its Board of Directors, effective August 10, 2025. Both appointees bring extensive financial and strategic leadership experience, which the company believes will enhance its growth strategy. Zymeworks is currently advancing its development programs, particularly with zanidatamab, which has received regulatory approvals in key markets. The company is optimistic about upcoming clinical data and its overall growth trajectory.

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ZYME
Aug 7, 2025
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Second Quarter 2025 Financial Results

Zymeworks Provides Corporate Update and Reports Second Quarter 2025 Financial Results

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ZYME
Aug 7, 2025
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Second Quarter 2025 Financial Results Investigational new drug (IND) application cleared by the United States Food and Drug Administration (FDA) for ZW251 with fir

Zymeworks Inc. reported its financial results for the second quarter of 2025, detailing significant progress including the FDA's clearance of their IND application for ZW251. The company highlighted international approval for zanidatamab in the treatment of HER2-positive biliary tract cancer and substantial revenue increases from existing partnerships in the quarter. With a strong cash position of $333.4 million, Zymeworks plans to initiate multiple Phase 1 trials in the coming year and aligns its strategy around anticipated milestone streams and royalty revenues. This update reflects the company's ongoing commitment to advancing its oncology and other therapeutic programs.

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ZYME
Jul 28, 2025
ZYMEFDA Updates

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate

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ZYME
Jul 17, 2025
ZYMEConferences/Events
▲ +7.1%on this news

Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025

Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025

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ZYME
Jul 10, 2025
ZYMEGeneral

Zymeworks Wins Life Sciences BC 2025 Company of the Year Award

Zymeworks Wins Life Sciences BC 2025 Company of the Year Award

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ZYME
May 30, 2025
ZYMEFDA Updates

Zymeworks Announces NMPA Approval of Zanidatamab in China for Adults with Previously Treated, Unresectable or Metastatic HER2-high expression (IHC3+) Biliary Tract Cancer Zanidatamab is the first and only dual HER2-targe

Zymeworks Inc. has announced that the National Medical Products Administration (NMPA) in China has granted conditional approval for zanidatamab, a dual HER2-targeted bispecific antibody, for the treatment of adults with previously treated unresectable or metastatic HER2-positive biliary tract cancer. This marks a significant milestone as it is the first antibody of its kind approved for this indication in China. The approval brings hope to patients with high unmet needs and poor prognoses and could potentially benefit Zymeworks financially through milestone payments and royalties.

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ZYME
May 22, 2025
ZYMEConferences/Events

Zymeworks Announces Presentations Highlighting Breadth of Oncology Portfolio at Upcoming Medical Conferences

Zymeworks Announces Presentations Highlighting Breadth of Oncology Portfolio at Upcoming Medical Conferences

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ZYME
May 19, 2025
ZYMEPhases

Zymeworks Presents Preclinical Data on ZW1528 at the American Thoracic Society International Conference

Zymeworks Presents Preclinical Data on ZW1528 at the American Thoracic Society International Conference

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ZYME
May 8, 2025
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports First Quarter 2025 Financial Results

Zymeworks Provides Corporate Update and Reports First Quarter 2025 Financial Results

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ZYME
May 8, 2025
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports First Quarter 2025 Financial Results Six posters presented at the American Association for Cancer Research (AACR) annual meeting Appointment of Dr. Sabeen Mekan as

Zymeworks has provided a corporate update and reported its first quarter 2025 financial results, revealing $321.6 million in cash resources. The company presented six posters during the AACR annual meeting, highlighting advancements in its biotherapeutic pipeline. Additionally, Dr. Sabeen Mekan has been appointed as Senior Vice President of Clinical Development, bringing extensive experience to further enhance the company's oncology portfolio. Zymeworks remains well-capitalized and poised for ongoing developments in cancer treatment and other diseases.

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ZYME
Apr 25, 2025
ZYMEPhases

Zymeworks Presents New Data from Multiple Development Programs at 2025 AACR Annual Meeting

Zymeworks Presents New Data from Multiple Development Programs at 2025 AACR Annual Meeting

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ZYME
Apr 21, 2025
ZYMEGeneral

Zymeworks Appoints Dr. Sabeen Mekan as Senior Vice President, Clinical Development

Zymeworks Appoints Dr. Sabeen Mekan as Senior Vice President, Clinical Development

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ZYME
Apr 17, 2025
ZYMEConferences/Events

Zymeworks to Report First Quarter 2025 Financial Results and Host Conference Call on May 8, 2025

Zymeworks to Report First Quarter 2025 Financial Results and Host Conference Call on May 8, 2025

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ZYME
Mar 31, 2025
ZYMEPhases

Zymeworks to Present Preclinical Data on ZW1528 at the American Thoracic Society Annual Meeting

Zymeworks to Present Preclinical Data on ZW1528 at the American Thoracic Society Annual Meeting

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ZYME
Mar 25, 2025
ZYMEPhases

Zymeworks to Present Preclinical Data on T cell Engager and Antibody-Drug Conjugate Platforms in Six Posters at AACR Annual Meeting

Zymeworks to Present Preclinical Data on T cell Engager and Antibody-Drug Conjugate Platforms in Six Posters at AACR Annual Meeting

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ZYME
Mar 5, 2025
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2024 Financial Results First-in-human global studies initiated for ZW191, an antibody-drug conjugate (ADC) engineered to target folate

Zymeworks Inc. has provided a corporate update alongside its fourth quarter and full year 2024 financial results. The company has initiated first-in-human studies for two key candidates, ZW191 and ZW171, targeting specific cancer indications. Additionally, the FDA granted accelerated approval for Ziihera, expanding Zymeworks' commercial opportunities. Financially, Zymeworks reported $324.2 million in cash resources and aims to utilize these funds into 2027, though it has paused the Phase 1 studies of ZW220 amid resource shifts.

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ZYME
Mar 5, 2025
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2024 Financial Results

Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2024 Financial Results

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ZYME
Feb 26, 2025
ZYMEGeneral

Zymeworks Announces Achievement of $14 Million Milestone from GSK Collaboration

Zymeworks Announces Achievement of $14 Million Milestone from GSK Collaboration

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ZYME
Feb 18, 2025
ZYMEGeneral

Zymeworks Announces Appointment of Oleg Nodelman to Board of Directors Vancouver, British Columbia (

Zymeworks Inc. has announced the appointment of Oleg Nodelman to its board of directors, effective February 17, 2025. Nodelman, the Founder and Managing Director of EcoR1 Capital, brings over two decades of investment management experience in biotechnology. His appointment is part of Zymeworks' ongoing board renewal process aimed at leveraging expertise to enhance growth and support the company's mission of developing innovative therapies. This restructuring aligns with Zymeworks’ commitments toward addressing challenging medical conditions such as cancer and autoimmune diseases.

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ZYME
Feb 13, 2025
ZYMEConferences/Events

Zymeworks To Report Fourth Quarter and Full Year 2024 Financial Results and Host Conference Call on March 5, 2025

Zymeworks To Report Fourth Quarter and Full Year 2024 Financial Results and Host Conference Call on March 5, 2025

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ZYME
Jan 8, 2025
ZYMEGeneral

Zymeworks Outlines Strategic Priorities and Outlook for 2025 and 2026

Zymeworks Outlines Strategic Priorities and Outlook for 2025 and 2026

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ZYME
Dec 31, 2024
ZYMEClinical Trials

Zymeworks Outlines Strategic Priorities and Outlook for 2025 and 2026 Investigational new drug (IND) applications for initiating first-in-human studies for ZW220 and ZW251 in solid tumors anticipated in 2025 IND applicat

Zymeworks Inc. has outlined its strategic priorities for 2025 and 2026, highlighting a pipeline of investigational new drugs aimed at treating solid tumors. The company has reported significant achievements, including FDA approval for zanidatamab and strong financial resources. They anticipate initiating first-in-human studies for ZW220 and ZW251 in 2025. Zymeworks plans to present at the J.P. Morgan Healthcare Conference in January 2025 to further discuss its innovative approaches and pipeline advancements.

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ZYME
Dec 12, 2024
ZYMEConferences/Events

Zymeworks Hosts R&D Day Highlighting Continued Clinical Progress in Oncology Programs and Expansion into Autoimmune and Inflammatory Diseases

Zymeworks Hosts R&D Day Highlighting Continued Clinical Progress in Oncology Programs and Expansion into Autoimmune and Inflammatory Diseases

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ZYME
Nov 21, 2024
ZYMEFDA Updates
▼ -6%on this news

FDA Grants U.S. Approval of Ziihera (zanidatamab-hrii) for the Treatment of Adults with Previously Treated, Unresectable or Metastatic HER2-positive (IHC 3+) Biliary Tract Cancer (BTC) Ziihera is the first and only dual

Zymeworks Inc. announced FDA approval for Ziihera (zanidatamab-hrii), a dual HER2-targeted therapy for adults with previously treated, unresectable or metastatic HER2-positive biliary tract cancer. The drug gained accelerated approval following promising clinical trial results demonstrating a 52% objective response rate and a median duration of response of 14.9 months. Zymeworks has partnered with Jazz Pharmaceuticals for its development and commercialization rights, earning an initial milestone payment of $25 million. Continued approval will depend on further confirmation of clinical benefits in ongoing trials.

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ZYME
Nov 7, 2024
ZYMEPhases
▲ +7.4%on this news

Zymeworks Presents Preclinical Data on ZW171 at the Society for Immunotherapy of Cancer (SITC) Conference

Zymeworks Presents Preclinical Data on ZW171 at the Society for Immunotherapy of Cancer (SITC) Conference

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ZYME
Nov 5, 2024
ZYMEPhases

Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW191 in Folate Receptor-⍺ Expressing Advanced Solid Tumors

Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW191 in Folate Receptor-⍺ Expressing Advanced Solid Tumors

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ZYME
Oct 31, 2024
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Third Quarter 2024 Financial Results

Zymeworks Provides Corporate Update and Reports Third Quarter 2024 Financial Results

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ZYME
Oct 31, 2024
ZYMEPhases

Document Zymeworks Provides Corporate Update and Reports Third Quarter 2024 Financial Results First patient dosed in Phase 1 clinical trial evaluating ZW171 in advanced mesothelin (MSLN)-expressing cancers Preclinical da

Zymeworks Inc. reported its third quarter 2024 financial results, highlighting the dosing of the first patient in a Phase 1 trial evaluating ZW171. The company also presented preclinical data on promising candidates ZW220 and ZW251. With $374.9 million in cash available, Zymeworks anticipates a solid cash runway into the second half of 2027. Additionally, potential breakthroughs are on the horizon with partner Jazz Pharmaceuticals' zanidatamab expected for a potential FDA approval in late November 2024 for patients with biliary tract cancer.

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ZYME
Oct 25, 2024
ZYMEPhases

Zymeworks Presents New Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference

Zymeworks Presents New Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference

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ZYME
Oct 21, 2024
ZYMEPhases

Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW171 in Advanced Mesothelin-Expressing Cancers

Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW171 in Advanced Mesothelin-Expressing Cancers

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ZYME
Oct 10, 2024
ZYMEConferences/Events

Zymeworks To Report Third Quarter 2024 Financial Results and Host Conference Call on October 31, 2024

Zymeworks To Report Third Quarter 2024 Financial Results and Host Conference Call on October 31, 2024

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ZYME
Oct 8, 2024
ZYMEGeneral

Dr. Raffaele Colombo Honored as a PharmaVoice 100 Winner

Dr. Raffaele Colombo Honored as a PharmaVoice 100 Winner

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ZYME
Oct 7, 2024
ZYMEConferences/Events

Zymeworks Announces Upcoming Scientific Presentation at the Society for Immunotherapy of Cancer Annual Meeting

Zymeworks Announces Upcoming Scientific Presentation at the Society for Immunotherapy of Cancer Annual Meeting

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ZYME
Sep 18, 2024
ZYMEPhases

Zymeworks to Present Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference

Zymeworks to Present Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference

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ZYME
Sep 16, 2024
ZYMEPhases

Zymeworks Presents Updated Phase 2 Data for Zanidatamab Demonstrating Increased mPFS in HER2-Positive Metastatic Gastroesophageal Adenocarcinoma at ESMO 2024

Zymeworks Presents Updated Phase 2 Data for Zanidatamab Demonstrating Increased mPFS in HER2-Positive Metastatic Gastroesophageal Adenocarcinoma at ESMO 2024

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ZYME
Sep 9, 2024
ZYMEPhases

Zymeworks Showcases New and Updated Clinical Data for Zanidatamab at ESMO 2024

Zymeworks Showcases New and Updated Clinical Data for Zanidatamab at ESMO 2024

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ZYME
Aug 1, 2024
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Second Quarter 2024 Financial Results

Zymeworks Provides Corporate Update and Reports Second Quarter 2024 Financial Results

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ZYME
Aug 1, 2024
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Second Quarter 2024 Financial Results Reported $395.9 million in cash resources as of

Zymeworks has provided a corporate update alongside its Q2 2024 financial results, reporting significant cash resources of $395.9 million, ensuring operational runway into the second half of 2027. Key developments include the Priority Review designation granted for zanidatamab as a second-line treatment for HER2-positive biliary tract cancer, with a target action date set for November 2024. Additionally, the FDA has cleared IND applications for two investigational products, ZW171 and ZW191, with clinical trials set to commence in the latter half of 2024. Notably, the company has also made the decision to discontinue the development of zanidatamab zovodotin, redirecting resources to more promising candidates.

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ZYME
Aug 1, 2024
ZYMEGeneral

Zymeworks Announces Share Repurchase Program of up to $60 Million of its Common Stock Zymeworks intends to commence the Share Repurchase Program with $30.0 million in initial repurchases anticipated to begin promptly and

Zymeworks Inc. has announced a Share Repurchase Program amounting to $60 million to buy back its common stock. The company plans to initiate this program with an immediate repurchase of $30 million, reflecting its confidence in future prospects and commitment to delivering value to shareholders. The remaining $30 million is reserved for future repurchases based on market conditions, showcasing strategic flexibility. Overall, this initiative is aimed at enhancing shareholder value while supporting ongoing growth opportunities.

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ZYME
Jul 25, 2024
ZYMEGeneral

Zymeworks Appoints Leone Patterson as Chief Business and Financial Officer Vancouver, British Columbia (

Zymeworks Inc. has announced the appointment of Leone Patterson as its Chief Business and Financial Officer, effective September 1, 2024. Patterson, who has over 20 years of experience in the biotechnology sector, is expected to play a vital role in guiding the company's financial strategies and supporting its growth objectives. This leadership change comes as Zymeworks aims to enhance its pipeline of novel therapies aimed at difficult-to-treat diseases. Zymeworks continues to make progress towards its strategic goals, which include advancing multiple product candidates into clinical studies in the coming years.

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ZYME
Jul 22, 2024
ZYMEFDA Updates

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW191, a Novel Folate Receptor-⍺ Targeted Topoisomerase I Inhibitor Antibody-Drug Conjugate

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW191, a Novel Folate Receptor-⍺ Targeted Topoisomerase I Inhibitor Antibody-Drug Conjugate

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ZYME
Jul 11, 2024
ZYMEConferences/Events
▲ +6.8%on this news

Zymeworks To Report Second Quarter 2024 Financial Results and Host Conference Call on August 1, 2024

Zymeworks To Report Second Quarter 2024 Financial Results and Host Conference Call on August 1, 2024

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ZYME
Jun 17, 2024
ZYMEFDA Updates
▼ -5.5%on this news

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW171, a novel 2+1 T-cell Targeting Bispecific Antibody for Mesothelin-expressing Cancers

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW171, a novel 2+1 T-cell Targeting Bispecific Antibody for Mesothelin-expressing Cancers

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ZYME
Jun 10, 2024
ZYMEGeneral

Zymeworks Announces China NMPA Acceptance of Biologics License Application for Zanidatamab for Second-Line Treatment of Biliary Tract Cancer

Zymeworks Announces China NMPA Acceptance of Biologics License Application for Zanidatamab for Second-Line Treatment of Biliary Tract Cancer

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ZYME
May 29, 2024
ZYMEGeneral

Introducing Pride in Biotech

Introducing Pride in Biotech

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ZYME
May 29, 2024
ZYMEFDA Updates

Zanidatamab Granted Priority Review for HER2-Positive Metastatic Biliary Tract Cancer

Zanidatamab Granted Priority Review for HER2-Positive Metastatic Biliary Tract Cancer

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ZYME
May 2, 2024
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports First Quarter 2024 Financial Results

Zymeworks Provides Corporate Update and Reports First Quarter 2024 Financial Results

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ZYME
May 2, 2024
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports First Quarter 2024 Financial Results Reported $420.5 million in cash resources as of

Zymeworks Inc. reported its financial results for Q1 2024, revealing $420.5 million in cash resources that could sustain its operations until mid-2027. The company progresses its pipeline, particularly with zanidatamab for biliary tract cancers, as they anticipate a Phase 3 trial initiation later this year. Despite a significant decrease in revenue compared to the previous year, Zymeworks remains committed to advancing innovative solutions in oncology. The company also plans to submit two investigational new drug applications this year, reinforcing its development strategy.

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ZYME
Apr 11, 2024
ZYMEConferences/Events

Zymeworks To Report First Quarter 2024 Financial Results and Host Conference Call on May 2, 2024

Zymeworks To Report First Quarter 2024 Financial Results and Host Conference Call on May 2, 2024

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ZYME
Apr 8, 2024
ZYMEPhases

Zymeworks Presents New Data from Multiple Preclinical Development Programs at 2024 American Association for Cancer Research Annual Meeting

Zymeworks Presents New Data from Multiple Preclinical Development Programs at 2024 American Association for Cancer Research Annual Meeting

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ZYME
Apr 2, 2024
ZYMEGeneral
▼ -6.6%on this news

Zanidatamab Biologics License Application for Previously Treated HER2-Positive Metastatic Biliary Tract Cancer Completed

Zanidatamab Biologics License Application for Previously Treated HER2-Positive Metastatic Biliary Tract Cancer Completed

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ZYME
Mar 28, 2024
ZYMEGeneral

Zymeworks Announces Appointment of Dr. Neil Gallagher to its Board of Directors Vancouver, British Columbia (

Zymeworks Inc. has announced the appointment of Dr. Neil Gallagher to its Board of Directors, effective April 2, 2024. Dr. Gallagher brings over 20 years of experience in drug development, particularly in oncology, and is expected to enhance the company's governance and oversight. His leadership will aid in advancing Zymeworks' clinical programs and expanding its pipeline of biotherapeutics. This staffing move reflects the company's ongoing commitment to improving the standard of care for patients with challenging diseases.

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ZYME
Mar 6, 2024
ZYMEFDA Updates

Document Zymeworks Reports Fourth Quarter and Full Year 2023 Financial Results Reported $456.3 million in cash resources as of

Zymeworks Inc. reported a strong financial position with $456.3 million in cash as of December 31, 2023, allowing projected operational capacity into 2027. The company announced the initiation of a rolling biologics license application (BLA) for its drug zanidatamab in the U.S. for biliary tract cancers, with expected regulatory submission completion set for the first half of 2024. Additionally, two investigational new drug (IND) submissions are planned for the current year, highlighting Zymeworks' commitment to progressing its clinical and preclinical pipeline in innovative therapies. Upcoming data from pivotal trials and presentations at major conferences further indicate a transformative year ahead for the biopharma company.

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ZYME
Mar 6, 2024
ZYMEGeneral

Zymeworks Reports Fourth Quarter and Full Year 2023 Financial Results

Zymeworks Reports Fourth Quarter and Full Year 2023 Financial Results

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ZYME
Mar 5, 2024
ZYMEPhases

Zymeworks to Present Preclinical Data on Antibody-Drug Conjugate and Multispecific Platforms at the American Association for Cancer Research Annual Meeting

Zymeworks to Present Preclinical Data on Antibody-Drug Conjugate and Multispecific Platforms at the American Association for Cancer Research Annual Meeting

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ZYME
Feb 14, 2024
ZYMEConferences/Events

Zymeworks To Host Fourth Quarter and Full Year 2023 Results Conference Call

Zymeworks To Host Fourth Quarter and Full Year 2023 Results Conference Call

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ZYME
Feb 8, 2024
ZYMEGeneral

Zymeworks Announces Appointment of Dr. Alessandra Cesano to its Board of Directors Vancouver, British Columbia (

Zymeworks Inc. has appointed Dr. Alessandra Cesano to its board of directors, effective February 8, 2024, succeeding Dr. Kenneth Hillan. Dr. Cesano's extensive experience in drug development and cancer immunology is expected to enhance the company's governance and pipeline of therapeutics. Her prior roles include serving as Chief Medical Officer at ESSA Pharmaceuticals and NanoString Technologies. Zymeworks aims to leverage her expertise as it focuses on advancing novel oncology treatments for difficult-to-treat cancers.

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ZYME
Jan 4, 2024
ZYMEGeneral

Zymeworks Outlines Strategic Priorities and Outlook for 2024 and 2025

Zymeworks Outlines Strategic Priorities and Outlook for 2024 and 2025

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ZYME
Jan 4, 2024
ZYMEGeneral

Zymeworks Announces Additional Leadership Appointments

Zymeworks Announces Additional Leadership Appointments

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ZYME
Dec 31, 2023
ZYMEGeneral

Zymeworks Outlines Strategic Priorities and Outlook for 2024 and 2025 Company well-positioned for further progress and broadening of R&D pipeline Cash resources of approximately $455 million as of

Zymeworks Inc. has outlined its strategic priorities for 2024 and 2025, emphasizing its strong financial position with approximately $455 million in cash resources. The company is focused on advancing multiple candidates, including zanidatamab, with significant upcoming clinical trials and potential regulatory approvals in 2025. Leadership changes and a commitment to expand their research pipeline indicate a proactive approach to enhancing their therapeutics portfolio. Zymeworks aims to leverage strategic partnerships to further support their objectives.

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ZYME
Dec 26, 2023
ZYMEGeneral
▲ +8.6%on this news

Zymeworks Announces $50 Million Private Placement to EcoR1 Capital Proceeds expected to extend cash runway into H2 2027 Vancouver, British Columbia (

Zymeworks Inc. has announced a $50 million private placement with EcoR1 Capital to extend its cash runway into the second half of 2027. The proceeds will support the company's 5 by 5 research and development strategy, aiding in the advancement of upcoming investigational new drug application filings for ZW171 and ZW191 in 2024. The private placement, which involves the sale of pre-funded warrants, is expected to close around December 28, 2023, subject to certain closing conditions.

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ZYME
Dec 15, 2023
ZYMEGeneral

Zymeworks Added to Nasdaq Biotechnology Index

Zymeworks Added to Nasdaq Biotechnology Index

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ZYME
Dec 8, 2023
ZYMEPhases

Updated Phase 2a Data Showcasing Potential of Zanidatamab in HER2+/HR+ Metastatic Breast Cancer Presented at SABCS 2023

Updated Phase 2a Data Showcasing Potential of Zanidatamab in HER2+/HR+ Metastatic Breast Cancer Presented at SABCS 2023

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ZYME
Nov 30, 2023
ZYMEConferences/Events

Zymeworks Announces Participation in Upcoming Investor Conference

Zymeworks Announces Participation in Upcoming Investor Conference

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ZYME
Nov 7, 2023
ZYMEGeneral

Zymeworks Provides Corporate Update And Reports Third Quarter 2023 Financial Results

Zymeworks Provides Corporate Update And Reports Third Quarter 2023 Financial Results

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ZYME
Nov 7, 2023
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Third Quarter 2023 Financial Results Net l oss for the first nine months of 20 23 decreased by 44% as compared to the same period in 2022 Cash resources of $390.2

Zymeworks Inc. reported a 44% decrease in net loss for the first nine months of 2023 compared to the same period in 2022, with cash resources of $390.2 million supporting operations through 2026. At the ESMO Annual Congress, positive clinical results for zanidatamab were shared, showing significant antitumor activity and improved quality of life outcomes for patients. Zymeworks has identified ZW251, a new antibody drug conjugate candidate, expecting an IND submission in late 2025, representing a strategic advancement in their product portfolio. Additionally, the company has reacquired rights for zanidatamab zovodotin to advance its clinical development independently.

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ZYME
Nov 4, 2023
ZYMEPhases

Zymeworks Presents Preclinical Data on Trispecific T Cell Engager Therapeutic Programs at the Society for Immunotherapy of Cancer (SITC) Conference

Zymeworks Presents Preclinical Data on Trispecific T Cell Engager Therapeutic Programs at the Society for Immunotherapy of Cancer (SITC) Conference

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ZYME
Oct 20, 2023
ZYMEPhases

Zymeworks Showcases Updated Clinical Data for Zanidatamab at the 2023 ESMO Annual Congress

Zymeworks Showcases Updated Clinical Data for Zanidatamab at the 2023 ESMO Annual Congress

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ZYME
Oct 17, 2023
ZYMEConferences/Events

Zymeworks To Host Third Quarter 2023 Results Conference Call

Zymeworks To Host Third Quarter 2023 Results Conference Call

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ZYME
Oct 16, 2023
ZYMEGeneral
▲ +8.5%on this newsshared move

Zymeworks Announces New Director Nominee VANCOUVER, British Columbia

Zymeworks Inc. has announced the nomination of Dr. Nancy Davidson to its board of directors during the upcoming annual general meeting on December 7, 2023. This addition is part of the company's strategy to promote diversity in leadership as it aims for five IND filings by the end of 2027. Dr. Davidson is an established expert in oncology, particularly breast cancer, and brings a wealth of clinical experience to the board. Her role is expected to significantly support Zymeworks' goals in developing and commercializing innovative therapies for difficult-to-treat cancers.

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ZYME
Oct 16, 2023
ZYMEGeneral
▲ +8.5%on this newsshared move

Zymeworks Announces New Director Nominee

Zymeworks Announces New Director Nominee

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ZYME
Oct 16, 2023
ZYMEGeneral
▲ +8.5%on this newsshared move

Jazz Pharmaceuticals to Showcase Growing Impact in Solid Tumor Oncology Research at ESMO 2023

Jazz Pharmaceuticals to Showcase Growing Impact in Solid Tumor Oncology Research at ESMO 2023

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ZYME
Sep 27, 2023
ZYMEConferences/Events

Zymeworks to Present on Clinical and Preclinical Programs at Multiple Upcoming Medical Conferences

Zymeworks to Present on Clinical and Preclinical Programs at Multiple Upcoming Medical Conferences

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ZYME
Aug 10, 2023
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Second Quarter 2023 Financial Results Net loss for the first six months of 2023 decrease d by 45% as compared to the same period in 2022 Cash resources of $431.4 m

Zymeworks Inc. reported its financial results for the second quarter of 2023, highlighting a significant 45% reduction in net loss compared to the first half of 2022. The company maintains cash resources of $431.4 million, anticipated to fund operations through at least the end of 2026. Recent clinical results for zanidatamab were positively received at the ASCO Annual Meeting, showcasing its potential in treating HER2-amplified cancers. Additionally, Zymeworks announced the nomination of its next IND candidate, ZW220, expected to be filed in the first half of 2025, further advancing its pipeline of therapeutic candidates.

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ZYME
Aug 10, 2023
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Second Quarter 2023 Financial Results

Zymeworks Provides Corporate Update and Reports Second Quarter 2023 Financial Results

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ZYME
Jul 19, 2023
ZYMEConferences/Events

Zymeworks To Host Second Quarter 2023 Results Conference Call

Zymeworks To Host Second Quarter 2023 Results Conference Call

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ZYME
Jun 29, 2023
ZYMEGeneral

Zymeworks Appoints New Director Vancouver, British Columbia (

Zymeworks Inc. has appointed Carlos E. Campoy to its board of directors, effective June 30, 2023. Campoy succeeds Dr. Natalie Sacks, who has served successfully for six years. He brings over 25 years of financial and strategic leadership experience in the biotechnology sector to the role. The appointment comes at a crucial time for Zymeworks as it continues to develop novel biotherapeutics, particularly for treating difficult cancers.

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ZYME
Jun 29, 2023
ZYMEGeneral

Zymeworks Appoints New Director

Zymeworks Appoints New Director

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ZYME
Jun 26, 2023
ZYMEGeneral

Zymeworks Set To Join Russell 3000®, Russell 2000®, And Russell Microcap® Indexes

Zymeworks Set To Join Russell 3000®, Russell 2000®, And Russell Microcap® Indexes

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ZYME
Jun 2, 2023
ZYMEPhases

Jazz Pharmaceuticals and Zymeworks Present Positive Pivotal Phase 2b Trial Data at ASCO 2023 Evaluating Zanidatamab in HER2-Amplified Biliary Tract Cancers

Jazz Pharmaceuticals and Zymeworks Present Positive Pivotal Phase 2b Trial Data at ASCO 2023 Evaluating Zanidatamab in HER2-Amplified Biliary Tract Cancers

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ZYME
Jun 1, 2023
ZYMEConferences/Events

Zymeworks Announces Participation In Upcoming Investor Conferences

Zymeworks Announces Participation In Upcoming Investor Conferences

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ZYME
May 25, 2023
ZYMEPhases

Zymeworks Showcases New and Updated Clinical Data for Zanidatamab at ASCO 2023

Zymeworks Showcases New and Updated Clinical Data for Zanidatamab at ASCO 2023

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ZYME
May 18, 2023
ZYMEGeneral

Zymeworks Announces Departure of Neil Klompas, President and Chief Operating Officer Vancouver, British Columbia (

Zymeworks Inc. announced the departure of Neil Klompas, President and Chief Operating Officer, effective June 30, 2023. Klompas has been with the company since 2007 and played a crucial role in its growth and development. His departure has led to expressions of gratitude from the company's leaders, highlighting his contributions to its milestones. He will continue to serve as an advisor during the transition period, ensuring continuity in leadership as Zymeworks focuses on advancing its drug development initiatives.

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ZYME
May 8, 2023
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports First Quarter 2023 Financial Results Confirmed prior guidance on 2023 operating cash burn of between $90 and $120 million and cash runway through at least 2026, an

Zymeworks Inc. provided its corporate update and financial results for Q1 2023, confirming its operating cash burn guidance of $90-$120 million and cash runway through at least 2026. The company reported a 66% decrease in net quarterly loss, amounting to $24.4 million. It showcased its preclinical antibody-drug conjugate and multispecific antibody therapeutics pipeline at the AACR meeting and announced upcoming presentations at ASCO on its lead product zanidatamab. Zymeworks also strengthened its leadership team by adding Derek J. Miller to its Board of Directors.

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ZYME
May 8, 2023
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports First Quarter 2023 Financial Results

Zymeworks Provides Corporate Update and Reports First Quarter 2023 Financial Results

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ZYME
Apr 18, 2023
ZYMEConferences/Events

Zymeworks Presents New Data from Multiple Preclinical and Clinical Development Programs at the 2023 American Association for Cancer Research Annual Meeting ZW191 demonstrates strong responses in FR -low expressing patien

Zymeworks Inc. presented new data from its preclinical and clinical development programs during the 2023 American Association for Cancer Research Annual Meeting. Highlights included promising results for ZW191, an antibody-drug conjugate targeting the folate receptor alpha, and ZW171, designed for mesothelin-expressing tumors. These advancements are part of Zymeworks' strategy to expand its therapeutic offerings, with plans to introduce multiple new products into clinical studies by 2027. The developments signal significant progress in their ongoing research into cancer therapies.

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ZYME
Apr 17, 2023
ZYMEConferences/Events

Zymeworks To Host First Quarter 2023 Results Conference Call

Zymeworks To Host First Quarter 2023 Results Conference Call

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ZYME
Apr 10, 2023
ZYMEGeneral

Zymeworks Announces Appointment of Derek J. Miller to its Board of Directors Vancouver, British Columbia (

Zymeworks Inc. has appointed Derek J. Miller to its board of directors as of April 10, 2023. Miller brings over 20 years of experience in oncology and has previously held significant leadership roles in various biopharma companies. This move is positioned to strengthen Zymeworks' strategic direction, particularly in its collaboration with Jazz Pharmaceuticals and BeiGene on the development of zanidatamab and other antibody-drug conjugates. Miller expresses enthusiasm about contributing to Zymeworks' mission to improve patient outcomes.

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ZYME
Mar 14, 2023
ZYMEConferences/Events

Zymeworks To Present Updated Data On Multiple Product Candidates At The American Association For Cancer Research (AACR) Annual Meeting

Zymeworks To Present Updated Data On Multiple Product Candidates At The American Association For Cancer Research (AACR) Annual Meeting

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ZYME
Mar 7, 2023
ZYMEGeneral

Document Zymeworks Reports Fourth Quarter and Full Year 2022 Financial Results 2022 was a year of transformation and change reported $412.5 million in total revenue for the year ended

Zymeworks reported its fourth-quarter and full-year 2022 financial results, highlighting a notable transformation in its business operations. The company achieved total revenue of $412.5 million and reported a net income of $124.3 million, compared to a loss in the previous year. A significant collaboration agreement was formed with Jazz Pharmaceuticals to develop zanidatamab, which has shown promising results in clinical trials. Zymeworks also plans to advance multiple clinical trials and new product candidates through 2024 and beyond.

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ZYME
Mar 7, 2023
ZYMEGeneral

Zymeworks Reports Fourth Quarter and Full Year 2022 Financial Results

Zymeworks Reports Fourth Quarter and Full Year 2022 Financial Results

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ZYME
Feb 21, 2023
ZYMEConferences/Events

Zymeworks To Host Fourth Quarter And Full Year 2022 Results Conference Call

Zymeworks To Host Fourth Quarter And Full Year 2022 Results Conference Call

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ZYME
Jan 19, 2023
ZYMEPhases

Jazz Pharmaceuticals and Zymeworks Announce 84% Overall Survival at 18 Months from Phase 2 Trial Evaluating Zanidatamab in HER2-Expressing Metastatic Gastroesophageal Adenocarcinoma

Jazz Pharmaceuticals and Zymeworks Announce 84% Overall Survival at 18 Months from Phase 2 Trial Evaluating Zanidatamab in HER2-Expressing Metastatic Gastroesophageal Adenocarcinoma

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ZYME
Jan 17, 2023
ZYMEConferences/Events

Zymeworks Announces Abstract for Zanidatamab in HER2-Expressing Metastatic Gastroesophageal Adenocarcinoma at the American Society of Clinical Oncology’s Gastrointestinal Cancers Symposium (ASCO GI)

Zymeworks Announces Abstract for Zanidatamab in HER2-Expressing Metastatic Gastroesophageal Adenocarcinoma at the American Society of Clinical Oncology’s Gastrointestinal Cancers Symposium (ASCO GI)

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ZYME
Jan 4, 2023
ZYMEGeneral

Zymeworks Provides Corporate Update on Key Strategic Priorities and Outlook for 2023

Zymeworks Provides Corporate Update on Key Strategic Priorities and Outlook for 2023

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ZYME
Dec 31, 2022
ZYMEGeneral

Zymeworks Provides Corporate Update on Key Strategic Priorities and Outlook for 2023 Provides updated key priorities and focus on enterprise value framework Closing of Jazz Pharmaceuticals (Jazz) collaboration in fourth

Zymeworks Provides Corporate Update on Key Strategic Priorities and Outlook for 2023 Vancouver, British Columbia (January 04, 2023) Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing novel, multifunctional biotherapeutics, today announced updated k

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ZYME
Dec 21, 2022
ZYMEPhases
▲ +23.6%on this news

Jazz Pharmaceuticals and Zymeworks Announce Jazz has Confirmed Opt-in and Advances Partnership for Zanidatamab Follows positive top-line clinical data readout from HERIZON-BTC-01 pivotal trial in biliary tract cancers DU

Jazz Pharmaceuticals and Zymeworks Announce Jazz has Confirmed Opt-in and Advances Partnership for Follows positive top-line clinical data readout from HERIZON-BTC-01 pivotal trial in biliary tract cancers DUBLIN and VANCOUVER, Dec. 21, 2022 Jazz Pharmaceuticals plc (Nasdaq: J

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ZYME
Dec 19, 2022
ZYMEPhases
▲ +5.1%on this news· ran to +36% by day 3shared move

Zymeworks Announces Positive Topline Data in the Pivotal HERIZON-BTC-01 Trial of Zanidatamab Zanidatamab as monotherapy produced a confirmed objective response rate (cORR) of 41.3% and median duration of response of 12.9

Zymeworks Announces Positive Topline Data in the Pivotal HERIZON-BTC-01 Trial of Zanidatamab Vancouver, British Columbia (December 19, 2022) Zymeworks Inc. (NASDAQ: ZYME), a clinical-stage biotechnology company developing multifunctional biotherapeutics, today announced positiv

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ZYME
Dec 14, 2022
ZYMEPhases

Zanidatamab Clinical Data Selected For Presentation At The American Society Of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium

Zanidatamab Clinical Data Selected For Presentation At The American Society Of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium

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ZYME
Dec 9, 2022
ZYMEPhases
▼ -5.2%on this news· ran to -15% by day 1shared move

New Clinical Data for Zanidatamab in HER2+ /HR+ Metastatic Breast Cancer Presented Today at 2022 SABCS Results show overall confirmed objective response rate (cORR) of 33%, disease control rate (DCR) of 92%, and median p

New Clinical Data for Zanidatamab in HER2+ /HR+ Metastatic Breast Cancer Presented Today at 2022 SABCS Vancouver, British Columbia (December 9, 2022) Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today presen

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ZYME
Dec 5, 2022
ZYMEGeneral

Zymeworks to Transfer Stock Listing to Nasdaq Vancouver, British Columbia (

Zymeworks to Transfer Stock Listing to Nasdaq Vancouver, British Columbia (December 5, 2022) Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, announced today that it has elected to transfer its stock exchange li

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ZYME
Nov 29, 2022
ZYMEGeneral

Zymeworks Announces Expiration of Hart-Scott-Rodino Waiting Period for Zanidatamab License Agreement with Jazz Pharmaceuticals Vancouver, British Columbia (

Zymeworks Announces Expiration of Hart-Scott-Rodino Waiting Period for Zanidatamab License Agreement with Jazz Pharmaceuticals Vancouver, British Columbia (November 29, 2022) Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional bio

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ZYME
Nov 21, 2022
ZYMEConferences/Events

Zymeworks Announces Abstract For Zanidatamab In Late-Line HER2-Positive Metastatic Breast Cancer At The San Antonio Breast Cancer Symposium (SABCS)

Zymeworks Announces Abstract For Zanidatamab In Late-Line HER2-Positive Metastatic Breast Cancer At The San Antonio Breast Cancer Symposium (SABCS)

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ZYME
Nov 10, 2022
ZYMEPhases
▲ +9%on this news

Zymeworks Presents Preclinical Data on TLR7 ISACs technology at the Society for Immunotherapy of Cancer (SITC) Conference

Zymeworks Presents Preclinical Data on TLR7 ISACs technology at the Society for Immunotherapy of Cancer (SITC) Conference

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ZYME
Nov 8, 2022
ZYMEGeneral

Document Zymeworks Provides Corporate Update and Reports Third Quarter 2022 Financial Results Announced exclusive license agreement with Jazz Pharmaceuticals to develop and commercialize zanidatamab, Zymeworks' lead clin

Zymeworks Provides Corporate Update and Reports Third Quarter 2022 Financial Results Announced exclusive license agreement with Jazz Pharmaceuticals to develop and commercialize zanidatamab, Zymeworks' lead clinical candidate, for total potential payments of up to $1.76 billion

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ZYME
Nov 1, 2022
ZYMEGeneral

November is Stomach Cancer Awareness Month

November is Stomach Cancer Awareness Month

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ZYME
Oct 20, 2022
ZYMEConferences/Events

Zymeworks Early R&D Day Highlights Progress In Development Of Novel Pipeline Assets And Applications Of Proprietary Next-Generation Technology Platforms

Zymeworks Early R&D Day Highlights Progress In Development Of Novel Pipeline Assets And Applications Of Proprietary Next-Generation Technology Platforms

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ZYME
Oct 19, 2022
ZYMEGeneral
▲ +15.9%on this newsshared move

Jazz Pharmaceuticals and Zymeworks Announce Exclusive License Agreement to Develop and Commercialize Zanidatamab, a HER2-Targeted Bispecific Antibody Jazz to obtain exclusive development and commercialization rights in k

Jazz Pharmaceuticals and Zymeworks Announce Exclusive License Agreement to Develop and Commercialize Zanidatamab, a HER2-Targeted Bispecific Jazz to obtain exclusive development and commercialization rights in key markets including the U.S., Europe and Japan Zymeworks to receiv

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ZYME
Oct 5, 2022
ZYMEPhases

Zymeworks to Present Preclinical Data at the Society for Immunotherapy of Cancer (SITC) Conference

Zymeworks to Present Preclinical Data at the Society for Immunotherapy of Cancer (SITC) Conference

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ZYME
Oct 4, 2022
ZYMEConferences/Events

Zymeworks Announces Participation In Upcoming Investor Conferences And Early Research & Development Day

Zymeworks Announces Participation In Upcoming Investor Conferences And Early Research & Development Day

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ZYME
Sep 12, 2022
ZYMEPhases
▼ -5.4%on this news

Zymeworks Reports Preliminary Phase 1 Trial Results For Zanidatamab Zovodotin (ZW49) At European Society For Medical Oncology Annual Congress

Zymeworks Reports Preliminary Phase 1 Trial Results For Zanidatamab Zovodotin (ZW49) At European Society For Medical Oncology Annual Congress

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ZYME
Sep 4, 2022
ZYMEPhases
▼ -28.8%on this news

Zymeworks Announces Release of ESMO Abstract for Phase 1 Study of Zanidatamab Zovodotin (ZW49) in Solid Cancers

Zymeworks Announces Release of ESMO Abstract for Phase 1 Study of Zanidatamab Zovodotin (ZW49) in Solid Cancers

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ZYME
Aug 4, 2022
ZYMEGeneral
▲ +5.6%on this news

Zymeworks Provides Corporate Update And Reports Second Quarter 2022 Financial Results

Zymeworks Provides Corporate Update And Reports Second Quarter 2022 Financial Results

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ZYME
Jul 25, 2022
ZYMEPhases
▼ -6.7%on this news

Zymeworks Announces Oral Presentation Of Data From Phase 1 Study Of Zanidatamab Zovodotin (ZW49) In Solid Cancers At European Society For Medical Oncology (ESMO) Congress 2022 In Paris

Zymeworks Announces Oral Presentation Of Data From Phase 1 Study Of Zanidatamab Zovodotin (ZW49) In Solid Cancers At European Society For Medical Oncology (ESMO) Congress 2022 In Paris

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ZYME
Jul 21, 2022
ZYMEConferences/Events

Zymeworks To Host Second Quarter Results Conference Call

Zymeworks To Host Second Quarter Results Conference Call

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ZYME
Jul 11, 2022
ZYMEGeneral
▼ -9.7%on this news

Zymeworks Statement on U.S. Supreme Court Overturning Roe v. Wade

Zymeworks Statement on U.S. Supreme Court Overturning Roe v. Wade

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ZYME
Jun 27, 2022
ZYMEGeneral

Zymeworks Appoints Dr. Paul Moore As Chief Scientific Officer

Zymeworks Appoints Dr. Paul Moore As Chief Scientific Officer

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ZYME
May 27, 2022
ZYMEConferences/Events
▲ +7.8%on this news

Zymeworks Announces Participation In Upcoming Investor Conference

Zymeworks Announces Participation In Upcoming Investor Conference

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ZYME
May 26, 2022
ZYMEPhases
▲ +7.6%on this news· ran to +18% by day 3shared move

Clinical Data Demonstrating Promising Antitumor Activity with Zanidatamab in 1L Setting of HER2‑Positive Breast and Gastroesophageal Cancers to be Presented at ASCO 2022

Clinical Data Demonstrating Promising Antitumor Activity with Zanidatamab in 1L Setting of HER2‑Positive Breast and Gastroesophageal Cancers to be Presented at ASCO 2022

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ZYME
May 18, 2022
ZYMEConferences/Events
▼ -12.1%on this news

Zymeworks to Present Trials in Progress Poster for HERIZON-GEA-01 at ESMO GI

Zymeworks to Present Trials in Progress Poster for HERIZON-GEA-01 at ESMO GI

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ZYME
Apr 28, 2022
ZYMEPhases

Zymeworks Reports Last Patient Enrolled in Pivotal Study of Zanidatamab in Treatment of HER2-Expressing Late-Line Biliary Tract Cancer

Zymeworks Reports Last Patient Enrolled in Pivotal Study of Zanidatamab in Treatment of HER2-Expressing Late-Line Biliary Tract Cancer

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ZYME
Apr 27, 2022
ZYMEConferences/Events

Zymeworks Announces Presentations At 2022 American Society Of Clinical Oncology (ASCO) Annual Meeting

Zymeworks Announces Presentations At 2022 American Society Of Clinical Oncology (ASCO) Annual Meeting

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ZYME
Apr 19, 2022
ZYMEConferences/Events

Zymeworks To Host First Quarter 2022 Results Conference Call

Zymeworks To Host First Quarter 2022 Results Conference Call

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ZYME
Feb 24, 2022
ZYMEGeneral

Zymeworks Provides Corporate Update and Reports Year-End 2021 Financial Results

Zymeworks Provides Corporate Update and Reports Year-End 2021 Financial Results

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ZYME
Feb 8, 2022
ZYMEConferences/Events

Zymeworks To Host Fourth Quarter And Full Year 2021 Results Conference Call

Zymeworks To Host Fourth Quarter And Full Year 2021 Results Conference Call

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ZYME
Jan 19, 2022
ZYMEGeneral

Zymeworks Provides Corporate Update On Key Strategic Priorities And Outlook For 2022

Zymeworks Provides Corporate Update On Key Strategic Priorities And Outlook For 2022

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ZYME
Jan 6, 2022
ZYMEConferences/Events
▼ -6.8%on this news

Zymeworks To Present At 40th Annual J.P. Morgan Healthcare Conference

Zymeworks To Present At 40th Annual J.P. Morgan Healthcare Conference

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ZYME
Jan 5, 2022
ZYMEGeneral
▼ -6.8%on this newsshared move

Zymeworks Names Biotechnology Industry Leader Kenneth Galbraith as Chair and CEO to Succeed Dr. Ali Tehrani

Zymeworks Names Biotechnology Industry Leader Kenneth Galbraith as Chair and CEO to Succeed Dr. Ali Tehrani

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ZYME
Dec 9, 2021
ZYMEPhases
▼ -14.9%on this news

Zymeworks Announces Expansion of Zanidatamab Pivotal Trial in Asia in Collaboration with BeiGene and Associated Milestone Payment

Zymeworks Announces Expansion of Zanidatamab Pivotal Trial in Asia in Collaboration with BeiGene and Associated Milestone Payment

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ZYME
Dec 9, 2021
ZYMEConferences/Events
▼ -14.9%on this news

Zanidatamab Data Presented at the San Antonio Breast Cancer Symposium (SABCS) Demonstrate Encouraging Antitumor Activity in Heavily Pretreated Patients with HER2-Positive Breast Cancer

Zanidatamab Data Presented at the San Antonio Breast Cancer Symposium (SABCS) Demonstrate Encouraging Antitumor Activity in Heavily Pretreated Patients with HER2-Positive Breast Cancer

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ZYME
Dec 1, 2021
ZYMEGeneral

Zymeworks Announces Second Janssen Bispecific Antibody to Begin Clinical Development Utilizing Azymetric ™ and EFECT ™ Therapeutic Platforms

Zymeworks Announces Second Janssen Bispecific Antibody to Begin Clinical Development Utilizing Azymetric ™ and EFECT ™ Therapeutic Platforms

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ZYME
Nov 19, 2021
ZYMEConferences/Events

Zymeworks Announces Abstract for Zanidatamab in Late-Line HER2-Positive Breast Cancer at the San Antonio Breast Cancer Symposium (SABCS)

Zymeworks Announces Abstract for Zanidatamab in Late-Line HER2-Positive Breast Cancer at the San Antonio Breast Cancer Symposium (SABCS)

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ZYME
Nov 9, 2021
ZYMEPhases

Zymeworks Launches Global Phase 3 Zanidatamab Trial in First-Line HER2-Positive Gastroesophageal Adenocarcinoma (GEA)

Zymeworks Launches Global Phase 3 Zanidatamab Trial in First-Line HER2-Positive Gastroesophageal Adenocarcinoma (GEA)

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ZYME
Nov 8, 2021
ZYMEConferences/Events

Zymeworks to Present at Upcoming Investor Conferences

Zymeworks to Present at Upcoming Investor Conferences

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ZYME
Nov 3, 2021
ZYMEGeneral

Document Zymeworks Reports 2021 Third Quarter Financial Results

q3_2021xpressxre.htm EX-99.1 Document Zymeworks Reports 2021 Third Quarter Financial Results

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ZYME
Oct 26, 2021
ZYMEPhases

Zymeworks Announces Webcast to Present HERIZON-GEA-01 Pivotal Trial Design and Zanidatamab Commercial Strategy in Gastrointestinal Cancers

Zymeworks Announces Webcast to Present HERIZON-GEA-01 Pivotal Trial Design and Zanidatamab Commercial Strategy in Gastrointestinal Cancers

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ZYME
Oct 5, 2021
ZYMEPhases

Zymeworks and ALX Oncology Announce First Patient Dosed in Phase 1b/2 Clinical Trial of Zanidatamab and Evorpacept (ALX148) in Patients with Advanced HER2-Expressing Breast Cancer and Other Solid Tumors

Zymeworks and ALX Oncology Announce First Patient Dosed in Phase 1b/2 Clinical Trial of Zanidatamab and Evorpacept (ALX148) in Patients with Advanced HER2-Expressing Breast Cancer and Other Solid Tumors

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ZYME
Sep 16, 2021
ZYMEPhases
▲ +9.3%on this news

Zanidatamab Phase 2 Clinical Trial Demonstrates Promising Response Rate and Durability in First-Line HER2-Positive Gastroesophageal Adenocarcinoma (GEA) at the European Society for Medical Oncology (ESMO) Annual Congress

Zanidatamab Phase 2 Clinical Trial Demonstrates Promising Response Rate and Durability in First-Line HER2-Positive Gastroesophageal Adenocarcinoma (GEA) at the European Society for Medical Oncology (ESMO) Annual Congress

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ZYME
Sep 13, 2021
ZYMEConferences/Events

Zymeworks Announces Abstract for Zanidatamab in First-line HER2-Expressing Gastroesophageal Cancers (GEA) at the European Society for Medical Oncology (ESMO) Annual Congress

Zymeworks Announces Abstract for Zanidatamab in First-line HER2-Expressing Gastroesophageal Cancers (GEA) at the European Society for Medical Oncology (ESMO) Annual Congress

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ZYME
Aug 4, 2021
ZYMEGeneral

Document Zymeworks Reports 2021 Second Quarter Financial Results

q2_2021xpressxre.htm EX-99.1 Document Zymeworks Reports 2021 Second Quarter Financial Results

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ZYME
Aug 3, 2021
ZYMEPhases

Zymeworks Announces Milestone Payment as Janssen Achieves First Patient Dosed for its Bispecific Antibody Utilizing Zymeworks’ Azymetric ™ and EFECT ™ Therapeutic Platforms

Zymeworks Announces Milestone Payment as Janssen Achieves First Patient Dosed for its Bispecific Antibody Utilizing Zymeworks’ Azymetric ™ and EFECT ™ Therapeutic Platforms

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ZYME
Jul 28, 2021
ZYMEPhases

Zymeworks Announces First Patient with Advanced HER2-Positive Breast Cancer Dosed with Zanidatamab in Combination with Tukysa ® (Tucatinib) and Chemotherapy

Zymeworks Announces First Patient with Advanced HER2-Positive Breast Cancer Dosed with Zanidatamab in Combination with Tukysa ® (Tucatinib) and Chemotherapy

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ZYME
Jul 8, 2021
ZYMEConferences/Events

Zymeworks to Present at Ladenburg Thalmann Healthcare Conference

Zymeworks to Present at Ladenburg Thalmann Healthcare Conference

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ZYME
May 26, 2021
ZYMEConferences/Events

Zymeworks to Present at Jefferies Virtual Healthcare Conference

Zymeworks to Present at Jefferies Virtual Healthcare Conference

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ZYME
May 6, 2021
ZYMEGeneral

Annual General Meeting of Shareholders

Annual General Meeting of Shareholders

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ZYME
May 5, 2021
ZYMEGeneral

Document Zymeworks Reports 2021 First Quarter Financial Results

q1_2021xpressxre.htm EX-99.1 Document Zymeworks Reports 2021 First Quarter Financial Results

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ZYME
Apr 19, 2021
ZYMEGeneral

Zymeworks Announces Succession Plan for Chief Medical Officer

Zymeworks Announces Succession Plan for Chief Medical Officer

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ZYME
Apr 13, 2021
ZYMEConferences/Events

Zymeworks to Present at Bloom Burton Healthcare Conference

Zymeworks to Present at Bloom Burton Healthcare Conference

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ZYME
Apr 12, 2021
ZYMEConferences/Events

Zymeworks Showcases Preclinical Assets, Including New Therapeutic Platform, ProTECT ™ , and Zanidatamab Mechanisms of Action at AACR Annual Meeting

Zymeworks Showcases Preclinical Assets, Including New Therapeutic Platform, ProTECT ™ , and Zanidatamab Mechanisms of Action at AACR Annual Meeting

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ZYME
Mar 11, 2021
ZYMEConferences/Events

Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021

Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021

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ZYME
Feb 24, 2021
ZYMEGeneral

Document Zymeworks Reports 2020 Year-End Financial Results

Document Zymeworks Reports 2020 Year-End Financial Results

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ZYME
Feb 10, 2021
ZYMEGeneral

Zymeworks Expands Commercial Team and Creates New R&D Role

Zymeworks Expands Commercial Team and Creates New R&D Role

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ZYME
Feb 10, 2021
ZYMEConferences/Events

Zymeworks to Participate in Upcoming Investor Conferences and Events

Zymeworks to Participate in Upcoming Investor Conferences and Events

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ZYME
Jan 28, 2021
ZYMEGeneral

Zymeworks Advances HER2 Bispecific Antibody-Drug Conjugate, ZW49, into Expansion Cohort Stage of Clinical Development

Zymeworks Advances HER2 Bispecific Antibody-Drug Conjugate, ZW49, into Expansion Cohort Stage of Clinical Development

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ZYME
Jan 15, 2021
ZYMEConferences/Events

Zanidatamab Data Highlight Durable Antitumor Activity in HER2-Expressing Biliary Tract and Gastroesophageal Cancers at ASCO Gastrointestinal Cancers Symposium

Zanidatamab Data Highlight Durable Antitumor Activity in HER2-Expressing Biliary Tract and Gastroesophageal Cancers at ASCO Gastrointestinal Cancers Symposium

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ZYME
Jan 11, 2021
ZYMEGeneral

Zymeworks Highlights 2020 Achievements and Announces Corporate Priorities

Zymeworks Highlights 2020 Achievements and Announces Corporate Priorities

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ZYME
Jan 7, 2021
ZYMEConferences/Events

Zymeworks to Present at J.P. Morgan Healthcare Conference and Host Two Webcasts in January to Provide Updates on its Lead Clinical Programs Zanidatamab and ZW49

Zymeworks to Present at J.P. Morgan Healthcare Conference and Host Two Webcasts in January to Provide Updates on its Lead Clinical Programs Zanidatamab and ZW49

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ZYME
Dec 10, 2020
ZYMEPhases

Zanidatamab Clinical Data Selected for Oral Presentation at the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium

Zanidatamab Clinical Data Selected for Oral Presentation at the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium

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ZYME
Dec 2, 2020
ZYMEGeneral

Exelixis In-Licenses Iconic Therapeutics’ Tissue Factor-Targeting Antibody-Drug Conjugate Ahead of Planned Investigational New Drug Application

Exelixis In-Licenses Iconic Therapeutics’ Tissue Factor-Targeting Antibody-Drug Conjugate Ahead of Planned Investigational New Drug Application

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ZYME
Dec 1, 2020
ZYMEPhases

Zymeworks Announces Expansion of Zanidatamab Pivotal Trial in HER2-Amplified Biliary Tract Cancer in Asia in Collaboration with BeiGene

Zymeworks Announces Expansion of Zanidatamab Pivotal Trial in HER2-Amplified Biliary Tract Cancer in Asia in Collaboration with BeiGene

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ZYME
Nov 30, 2020
ZYMEFDA Updates

Zymeworks Receives FDA Breakthrough Therapy Designation for HER2-Targeted Bispecific Antibody Zanidatamab in Patients with Biliary Tract Cancer

Zymeworks Receives FDA Breakthrough Therapy Designation for HER2-Targeted Bispecific Antibody Zanidatamab in Patients with Biliary Tract Cancer

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ZYME
Nov 19, 2020
ZYMEFDA Updates

Zymeworks Receives Orphan Drug Designation from the European Commission for HER2-Targeted Bispecific Antibody Zanidatamab in Patients with Gastric Cancer

Zymeworks Receives Orphan Drug Designation from the European Commission for HER2-Targeted Bispecific Antibody Zanidatamab in Patients with Gastric Cancer

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ZYME
Nov 16, 2020
ZYMEGeneral

Zymeworks and ALX Oncology Announce Clinical Collaboration Evaluating Zanidatamab with the CD47 Blocker ALX148 in Patients with Advanced HER2-Expressing Breast Cancer

Zymeworks and ALX Oncology Announce Clinical Collaboration Evaluating Zanidatamab with the CD47 Blocker ALX148 in Patients with Advanced HER2-Expressing Breast Cancer

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ZYME
Nov 3, 2020
ZYMEGeneral

Document Zymeworks Reports 2020 Third Quarter Financial Results

Document Zymeworks Reports 2020 Third Quarter Financial Results

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ZYME
Aug 5, 2020
ZYMEGeneral

Document Zymeworks Reports 2020 Second Quarter Financial Results

q22020pressr.htm EX-99.1 Document Zymeworks Reports 2020 Second Quarter Financial Results

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ZYME
Jul 9, 2020
ZYMEConferences/Events

Corporate Update Webcast and Conference Call Summary

Corporate Update Webcast and Conference Call Summary

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ZYME
Jul 8, 2020
ZYMEGeneral

Zymeworks Announces New Multispecific Antibody Collaboration with Merck

Zymeworks Announces New Multispecific Antibody Collaboration with Merck

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ZYME
Jun 30, 2020
ZYMEConferences/Events

Zymeworks Announces Corporate Update Webcast and Conference Call

Zymeworks Announces Corporate Update Webcast and Conference Call

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ZYME
May 28, 2020
ZYMEConferences/Events

Zymeworks to Present at the Jefferies 2020 Virtual Healthcare Conference

Zymeworks to Present at the Jefferies 2020 Virtual Healthcare Conference

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ZYME
May 7, 2020
ZYMEGeneral

Document Zymeworks Reports 2020 First Quarter Financial Results

q12020pressr.htm EX-99.1 Document Zymeworks Reports 2020 First Quarter Financial Results

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ZYME
Apr 1, 2020
ZYMEPhases

Zymeworks Announces First Patient Dosed in Phase 1b/2 Trial of ZW25 in First-Line HER2-Positive Breast Cancer and Gastroesophageal Adenocarcinoma Conducted by BeiGene

Zymeworks Announces First Patient Dosed in Phase 1b/2 Trial of ZW25 in First-Line HER2-Positive Breast Cancer and Gastroesophageal Adenocarcinoma Conducted by BeiGene

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ZYME
Mar 16, 2020
ZYMEGeneral

Zymeworks Appoints Dr. Kelvin Neu to the Board of Directors

Zymeworks Appoints Dr. Kelvin Neu to the Board of Directors

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ZYME
Mar 2, 2020
ZYMEGeneral

Zymeworks Reports 2019 Year-End Financial Results

Zymeworks Reports 2019 Year-End Financial Results

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ZYME
Feb 24, 2020
ZYMEConferences/Events

Zymeworks to Present at Raymond James 41 st Annual Institutional Investors Conference

Zymeworks to Present at Raymond James 41 st Annual Institutional Investors Conference

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ZYME
Jan 27, 2020
ZYMEGeneral

Zymeworks Announces Closing of Public Offering and Exercise in Full of the Underwriters’ Over-Allotment Option to Purchase Additional Shares

Zymeworks Announces Closing of Public Offering and Exercise in Full of the Underwriters’ Over-Allotment Option to Purchase Additional Shares

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ZYME
Jan 24, 2020
ZYMEGeneral

Zymeworks Files Preliminary Prospectus Supplements for Offering of Common Shares and Pre-Funded Warrants

Zymeworks Files Preliminary Prospectus Supplements for Offering of Common Shares and Pre-Funded Warrants

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ZYME
Jan 13, 2020
ZYMEPhases

Zymeworks Announces Agreement with Pfizer and Initiation of a New Phase 2 Trial Evaluating ZW25 in Combination with Ibrance ® (palbociclib)

Zymeworks Announces Agreement with Pfizer and Initiation of a New Phase 2 Trial Evaluating ZW25 in Combination with Ibrance ® (palbociclib)

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ZYME
Jan 7, 2020
ZYMEConferences/Events

Zymeworks to Present at the J.P. Morgan Healthcare Conference 2020

Zymeworks to Present at the J.P. Morgan Healthcare Conference 2020

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ZYME
Nov 22, 2019
ZYMEGeneral

Zymeworks Highlights Advancing Clinical Collaboration with BeiGene and

Zymeworks Highlights Advancing Clinical Collaboration with BeiGene and

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ZYME
Nov 18, 2019
ZYMEConferences/Events

Zymeworks Announces Selection of ZW25 Abstract for Mini Oral Presentation at the European Society for Medical Oncology Asia (ESMO Asia) Congress

Zymeworks Announces Selection of ZW25 Abstract for Mini Oral Presentation at the European Society for Medical Oncology Asia (ESMO Asia) Congress

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ZYME
Nov 6, 2019
ZYMEGeneral

Zymeworks Files Automatic Shelf Registration Statement and Enters into At-The-Market Equity Offering Sales Agreement

Zymeworks Files Automatic Shelf Registration Statement and Enters into At-The-Market Equity Offering Sales Agreement

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ZYME
Nov 5, 2019
ZYMEGeneral

Zymeworks Reports 2019 Third Quarter Financial Results

Zymeworks Reports 2019 Third Quarter Financial Results

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ZYME
Nov 4, 2019
ZYMEConferences/Events

Zymeworks to Present at Stifel 2019 Healthcare Conference

Zymeworks to Present at Stifel 2019 Healthcare Conference

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ZYME
Oct 28, 2019
ZYMEPhases

Zymeworks Announces Phase 1 Data for ZW25 in Combination with

Zymeworks Announces Phase 1 Data for ZW25 in Combination with

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ZYME
Oct 16, 2019
ZYMEGeneral

Zymeworks Appoints Chief People Officer

Zymeworks Appoints Chief People Officer

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ZYME
Sep 30, 2019
ZYMEGeneral

Zymeworks Announces Updated Single Agent Data for HER2-Targeted Bispecific

Zymeworks Announces Updated Single Agent Data for HER2-Targeted Bispecific

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ZYME
Sep 18, 2019
ZYMEGeneral

Zymeworks Announces New Chair of Board of Directors and Voluntary Delisting from the TSX

Zymeworks Announces New Chair of Board of Directors and Voluntary Delisting from the TSX

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ZYME
Aug 28, 2019
ZYMEConferences/Events

Zymeworks to Participate in Upcoming Investor Conferences

Zymeworks to Participate in Upcoming Investor Conferences

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ZYME
Aug 2, 2019
ZYMEGeneral

Zymeworks Reports 2019 Second Quarter Financial Results

Zymeworks Reports 2019 Second Quarter Financial Results

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ZYME
Jul 16, 2019
ZYMEGeneral

Celgene Selects Lead Oncology Therapeutic Candidate Under Bispecific Antibody Collaboration with Zymeworks

Celgene Selects Lead Oncology Therapeutic Candidate Under Bispecific Antibody Collaboration with Zymeworks

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ZYME
Jun 20, 2019
ZYMEGeneral

5,555,556 Common Shares

5,555,556 Common Shares

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ZYME
Jun 13, 2019
ZYMEConferences/Events

Zymeworks to Present at Raymond James Life Sciences and MedTech Conference

Zymeworks to Present at Raymond James Life Sciences and MedTech Conference

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ZYME
Jun 5, 2019
ZYMEGeneral

Zymeworks Adds Accomplished Biopharmaceutical Executives to its Board of Directors

Zymeworks Adds Accomplished Biopharmaceutical Executives to its Board of Directors

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ZYME
May 30, 2019
ZYMEFDA Updates

Zymeworks’ Lead Asset, ZW25, Granted Fast Track Designation from the FDA

Zymeworks’ Lead Asset, ZW25, Granted Fast Track Designation from the FDA

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ZYME
May 29, 2019
ZYMEGeneral

Zymeworks Earns Milestone Payment in Merck Collaboration

Zymeworks Earns Milestone Payment in Merck Collaboration

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ZYME
May 28, 2019
ZYMEConferences/Events

Zymeworks to Present at Jefferies 2019 Global Healthcare Conference

Zymeworks to Present at Jefferies 2019 Global Healthcare Conference

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ZYME
May 24, 2019
ZYMEConferences/Events

Zymeworks Announces Corporate Update Conference Call

Zymeworks Announces Corporate Update Conference Call

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ZYME
May 17, 2019
ZYMEGeneral

Zymeworks and GSK Expand 2016 Azymetric TM Bispecific Agreement

Zymeworks and GSK Expand 2016 Azymetric TM Bispecific Agreement

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ZYME
May 15, 2019
ZYMEGeneral

Zymeworks Enters its First ZymeLink TM Antibody-Drug Conjugate Platform Licensing Agreement with Iconic Therapeutics

Zymeworks Enters its First ZymeLink TM Antibody-Drug Conjugate Platform Licensing Agreement with Iconic Therapeutics

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ZYME
May 2, 2019
ZYMEGeneral

Zymeworks Reports 2019 First Quarter Financial Results

Zymeworks Reports 2019 First Quarter Financial Results

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ZYME
Apr 30, 2019
ZYMEGeneral

Zymeworks Adds Experienced Executives to Management Team to Support Expanding Clinical Development

Zymeworks Adds Experienced Executives to Management Team to Support Expanding Clinical Development

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ZYME
Apr 25, 2019
ZYMEGeneral

Daiichi Sankyo Selects Lead Candidate Built on Zymeworks’ Azymetric™ Bispecific Platform

Daiichi Sankyo Selects Lead Candidate Built on Zymeworks’ Azymetric™ Bispecific Platform

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ZYME
Apr 23, 2019
ZYMEConferences/Events

Zymeworks to Present at Bloom Burton & Co. Healthcare Investor Conference 2019

Zymeworks to Present at Bloom Burton & Co. Healthcare Investor Conference 2019

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ZYME
Apr 15, 2019
ZYMEPhases

Zymeworks Opens Phase 2 Clinical Trial for ZW25 in First-Line HER2-Expressing Metastatic Gastroesophageal Cancers

Zymeworks Opens Phase 2 Clinical Trial for ZW25 in First-Line HER2-Expressing Metastatic Gastroesophageal Cancers

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ZYME
Mar 6, 2019
ZYMEGeneral

Zymeworks Reports 2018 Year-End Financial Results

Zymeworks Reports 2018 Year-End Financial Results

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ZYME
Mar 5, 2019
ZYMEConferences/Events

Zymeworks to Present at Barclays 2019 Global Healthcare Conference

Zymeworks to Present at Barclays 2019 Global Healthcare Conference

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ZYME
Jan 17, 2019
ZYMEGeneral

Zymeworks Reports Second Investigational New Drug (IND)-Submission

Zymeworks Reports Second Investigational New Drug (IND)-Submission

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ZYME
Jan 7, 2019
ZYMEGeneral

Zymeworks Highlights 2018 Achievements and Announces 2019 Priorities

Zymeworks Highlights 2018 Achievements and Announces 2019 Priorities

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ZYME
Dec 10, 2018
ZYMEConferences/Events

Zymeworks Submits Investigational New Drug (IND) Application for ZW49 and Presents IND‑Enabling Studies at the San Antonio Breast Cancer Symposium

Zymeworks Submits Investigational New Drug (IND) Application for ZW49 and Presents IND‑Enabling Studies at the San Antonio Breast Cancer Symposium

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ZYME
Nov 27, 2018
ZYMEGeneral

Zymeworks and BeiGene Announce License and Collaboration Agreement for Zymeworks’ HER2-Targeted Therapeutic Candidates, ZW25 and ZW49, in Asia-Pacific and Research and License Agreement for Zymeworks’ Azymetric™ and EFECT™ platforms globally

Zymeworks and BeiGene Announce License and Collaboration Agreement for Zymeworks’ HER2-Targeted Therapeutic Candidates, ZW25 and ZW49, in Asia-Pacific and Research and License Agreement for Zymeworks’ Azymetric™ and EFECT™ platforms globally

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ZYME
Nov 14, 2018
ZYMEPhases

Zymeworks Announces Updated Clinical Data for Novel Bispecific Antibody,

Zymeworks Announces Updated Clinical Data for Novel Bispecific Antibody,

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ZYME
Nov 6, 2018
ZYMEGeneral

Zymeworks Reports Financial Results for the Third Quarter of 2018

Zymeworks Reports Financial Results for the Third Quarter of 2018

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ZYME
Oct 30, 2018
ZYMEConferences/Events

Zymeworks Announces Selection of ZW25 Abstract for Plenary Session Presentation at the 30 th EORTC-NCI-AACR Symposium

Zymeworks Announces Selection of ZW25 Abstract for Plenary Session Presentation at the 30 th EORTC-NCI-AACR Symposium

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ZYME
Oct 26, 2018
ZYMEGeneral

Zymeworks and LEO Pharma Enter into Bispecific Antibody Licensing and Research Collaboration

Zymeworks and LEO Pharma Enter into Bispecific Antibody Licensing and Research Collaboration

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ZYME
Oct 4, 2018
ZYMEConferences/Events

Zymeworks to Webcast R&D Briefing

Zymeworks to Webcast R&D Briefing

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ZYME
Sep 25, 2018
ZYMEConferences/Events

Zymeworks to Present at Ladenburg Thalmann 2018 Healthcare Conference

Zymeworks to Present at Ladenburg Thalmann 2018 Healthcare Conference

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ZYME
Sep 19, 2018
ZYMEGeneral

Zymeworks Names Anthony Polverino, Ph.D., Executive Vice President of Early Development and Chief Scientific Officer

Zymeworks Names Anthony Polverino, Ph.D., Executive Vice President of Early Development and Chief Scientific Officer

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ZYME
Sep 4, 2018
ZYMEGeneral

Zymeworks Reports IND-Submission Milestone Achieved in Lilly Collaboration

Zymeworks Reports IND-Submission Milestone Achieved in Lilly Collaboration

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ZYME
Aug 29, 2018
ZYMEConferences/Events

Zymeworks to Present at Wells Fargo Healthcare Conference

Zymeworks to Present at Wells Fargo Healthcare Conference

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ZYME
Aug 2, 2018
ZYMEConferences/Events

Zymeworks to Present at Canaccord Genuity 38th Annual Growth Conference

Zymeworks to Present at Canaccord Genuity 38th Annual Growth Conference

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ZYME
Aug 1, 2018
ZYMEGeneral

Zymeworks Reports Financial Results for the Second Quarter of 2018

Zymeworks Reports Financial Results for the Second Quarter of 2018

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ZYME
Jun 14, 2018
ZYMEGeneral

Zymeworks Closes Previously Announced Public Offering

Zymeworks Closes Previously Announced Public Offering

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ZYME
Jun 8, 2018
ZYMEGeneral

5,400,000 Common Shares

5,400,000 Common Shares

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ZYME
Jun 8, 2018
ZYMEGeneral

Annual General and Special Meeting of Shareholders

Annual General and Special Meeting of Shareholders

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ZYME
Jun 7, 2018
ZYMEGeneral

MATERIAL CHANGE REPORT

MATERIAL CHANGE REPORT

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ZYME
Jun 1, 2018
ZYMEPhases

Clinical Data for Zymeworks’ Novel Bispecific Antibody, ZW25, Presented at the American Society of Clinical Oncology (ASCO) Annual Meeting

Clinical Data for Zymeworks’ Novel Bispecific Antibody, ZW25, Presented at the American Society of Clinical Oncology (ASCO) Annual Meeting

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ZYME
May 18, 2018
ZYMEGeneral

Zymeworks and Daiichi Sankyo Expand Immuno-Oncology Collaboration Focused on Bispecific Antibodies Two Additional Licenses Granted; Upfront Payment of US$18 Million; Total Potential Transaction Value of up to US$484.7 Million

Zymeworks and Daiichi Sankyo Expand Immuno-Oncology Collaboration Focused on Bispecific Antibodies Two Additional Licenses Granted; Upfront Payment of US$18 Million; Total Potential Transaction Value of up to US$484.7 Million

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ZYME
May 10, 2018
ZYMEConferences/Events

Zymeworks to Present at the UBS Global Healthcare Conference 2018

Zymeworks to Present at the UBS Global Healthcare Conference 2018

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ZYME
May 1, 2018
ZYMEGeneral

Zymeworks Reports 2018 First Quarter Financial Results

Zymeworks Reports 2018 First Quarter Financial Results

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ZYME
Apr 30, 2018
ZYMEConferences/Events

Zymeworks to Present at Bloom Burton & Co. Healthcare Investor Conference 2018

Zymeworks to Present at Bloom Burton & Co. Healthcare Investor Conference 2018

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ZYME
Apr 25, 2018
ZYMEConferences/Events

Zymeworks Announces Selection of ZW25 Abstract for Oral Presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting Data will Highlight the Single Agent Activity of ZW25, a HER2-Targeted Bispecific Antibody

Zymeworks Announces Selection of ZW25 Abstract for Oral Presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting Data will Highlight the Single Agent Activity of ZW25, a HER2-Targeted Bispecific Antibody

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ZYME
Apr 23, 2018
ZYMEGeneral

Zymeworks and Celgene Expand Bispecific Antibody Collaboration

Zymeworks and Celgene Expand Bispecific Antibody Collaboration

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ZYME
Apr 18, 2018
ZYMEPhases

Zymeworks Presents Preclinical Data at the Annual Meeting of the American Association for Cancer Research

Zymeworks Presents Preclinical Data at the Annual Meeting of the American Association for Cancer Research

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ZYME
Mar 14, 2018
ZYMEGeneral

Zymeworks Reports 2017 Year-End Financial Results

Zymeworks Reports 2017 Year-End Financial Results

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ZYME
Mar 7, 2018
ZYMEConferences/Events

Zymeworks to Present at Barclays 2018 Global Healthcare Conference

Zymeworks to Present at Barclays 2018 Global Healthcare Conference

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ZYME
Feb 28, 2018
ZYMEGeneral

Zymeworks Opening Clinical Sites in Canada

Zymeworks Opening Clinical Sites in Canada

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ZYME
Jan 8, 2018
ZYMEGeneral

Zymeworks Highlights Key 2017 Accomplishments and Announces 2018 Priorities Lead Asset (ZW25) Demonstrating Promising Clinical Activity; Growing Number of Pharmaceutical Partners Validate Bispecific Antibody Technology

Zymeworks Highlights Key 2017 Accomplishments and Announces 2018 Priorities Lead Asset (ZW25) Demonstrating Promising Clinical Activity; Growing Number of Pharmaceutical Partners Validate Bispecific Antibody Technology

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ZYME
Dec 5, 2017
ZYMEPhases

Zymeworks Presents Results of the Completed Dose Escalation Portion of the Ongoing Phase 1 Study of ZW25 at the San Antonio Breast Cancer Symposium Continued Clinical Benefit of Single Agent ZW25 in Heavily Pretreated HER2-High Patients

Zymeworks Presents Results of the Completed Dose Escalation Portion of the Ongoing Phase 1 Study of ZW25 at the San Antonio Breast Cancer Symposium Continued Clinical Benefit of Single Agent ZW25 in Heavily Pretreated HER2-High Patients

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ZYME
Nov 13, 2017
ZYMEGeneral

Zymeworks Announces License Agreement with Johnson & Johnson Innovation to Develop and Commercialize Next Generation Bispecific Antibody Therapeutics

Zymeworks Announces License Agreement with Johnson & Johnson Innovation to Develop and Commercialize Next Generation Bispecific Antibody Therapeutics

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ZYME
Nov 13, 2017
ZYMEConferences/Events

Zymeworks to Present at Upcoming 2017 Stifel Healthcare Conference

Zymeworks to Present at Upcoming 2017 Stifel Healthcare Conference

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ZYME
Nov 8, 2017
ZYMEGeneral

MANAGEMENT’S DISCUSSION AND ANALYSIS OF

MANAGEMENT’S DISCUSSION AND ANALYSIS OF

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ZYME
Nov 8, 2017
ZYMEGeneral

Zymeworks Reports Third Quarter 2017 Financial Results and Provides Business Update

Zymeworks Reports Third Quarter 2017 Financial Results and Provides Business Update

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ZYME
Sep 19, 2017
ZYMEGeneral

Merck to Advance Bispecific Antibody Drug Candidate Developed Using Zymeworks’ Azymetric™ Platform into Preclinical Development

Merck to Advance Bispecific Antibody Drug Candidate Developed Using Zymeworks’ Azymetric™ Platform into Preclinical Development

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ZYME
Sep 11, 2017
ZYMEPhases

Zymeworks Presents Additional Safety and Anti-Tumor Activity Data from the Ongoing Phase 1 Study of ZW25 at the European Society for Medical Oncology 2017 Congress (“ESMO”)

Zymeworks Presents Additional Safety and Anti-Tumor Activity Data from the Ongoing Phase 1 Study of ZW25 at the European Society for Medical Oncology 2017 Congress (“ESMO”)

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ZYME
Sep 6, 2017
ZYMEConferences/Events

Zymeworks to Present at the European Society for Medical Oncology 2017 Congress and Hold Webcast to Review Clinical Results

Zymeworks to Present at the European Society for Medical Oncology 2017 Congress and Hold Webcast to Review Clinical Results

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ZYME
Aug 8, 2017
ZYMEGeneral

Zymeworks Reports Second Quarter 2017 Financial Results

Zymeworks Reports Second Quarter 2017 Financial Results

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ZYME
Aug 4, 2017
ZYMEConferences/Events

Zymeworks to Host Second Quarter 2017 Financial Results Conference Call on August 8, 2017

Zymeworks to Host Second Quarter 2017 Financial Results Conference Call on August 8, 2017

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ZYME
Aug 4, 2017
ZYMEConferences/Events

Zymeworks to Present at 37 th Annual Canaccord Genuity Growth Conference

Zymeworks to Present at 37 th Annual Canaccord Genuity Growth Conference

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ZYME
Jul 18, 2017
ZYMEGeneral

Zymeworks and Daiichi Sankyo Announce Successful Achievement of a Research Milestone in Bispecific Antibody Collaboration

Zymeworks and Daiichi Sankyo Announce Successful Achievement of a Research Milestone in Bispecific Antibody Collaboration

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ZYME
Jun 12, 2017
ZYMEGeneral

Drug Candidates Developed Using Zymeworks’ Azymetric Platform Nominated for Late-Stage, Preclinical Development by Lilly June 12, 2017

Drug Candidates Developed Using Zymeworks’ Azymetric Platform Nominated for Late-Stage, Preclinical Development by Lilly June 12, 2017

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ZYME
Jun 7, 2017
ZYMEPhases

Zymeworks Presents Safety and Anti-Tumor Activity Data from the Ongoing Phase 1 Study of ZW25 at the American Society of Clinical Oncology Annual Meeting (ASCO 2017)

Zymeworks Presents Safety and Anti-Tumor Activity Data from the Ongoing Phase 1 Study of ZW25 at the American Society of Clinical Oncology Annual Meeting (ASCO 2017)

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ZYME
May 31, 2017
ZYMEGeneral

Zymeworks Announces Closing of Partial Exercise of Over-Allotment Option for its Initial Public Offering

Zymeworks Announces Closing of Partial Exercise of Over-Allotment Option for its Initial Public Offering

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ZYME
May 26, 2017
ZYMEGeneral

Zymeworks Announces Partial Exercise of Over-Allotment Option for its Initial Public Offering

Zymeworks Announces Partial Exercise of Over-Allotment Option for its Initial Public Offering

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ZYME
May 18, 2017
ZYMEConferences/Events

Zymeworks to Present at the 2017 American Society of Clinical Oncology Annual Meeting

Zymeworks to Present at the 2017 American Society of Clinical Oncology Annual Meeting

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ZYME
May 16, 2017
ZYMEGeneral

Zymeworks Reports First Quarter 2017 Financial Results

Zymeworks Reports First Quarter 2017 Financial Results

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ZYME
May 10, 2017
ZYMEGeneral

Zymeworks Thanks Resigning Directors For Their Service

Zymeworks Thanks Resigning Directors For Their Service

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ZYME
May 3, 2017
ZYMEGeneral

Zymeworks Announces Closing of Initial Public Offering

Zymeworks Announces Closing of Initial Public Offering

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ZYME
Apr 28, 2017
ZYMEGeneral

Zymeworks Announces Pricing of Initial Public Offering

Zymeworks Announces Pricing of Initial Public Offering

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