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FX-322

Phase 1

Hearing Loss | Small molecule | ENT |cbdMD, Inc.|Last Updated: Apr 12, 2018

Success Probability

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Market & Valuation

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Trial Design

PLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment9

FDA Designations

No designations recorded

Clinical trial landscape

FX-322 · 1 trial · 1 indication

Early Phase 1 1
NCT03300687First in Human Safety Study of FX-322 in Adults Undergoing Cochlear ImplantationHearing Loss
COMPLETED9 Analytics
EARLY_PHASE1COMPLETED
First in Human Safety Study of FX-322 in Adults Undergoing Cochlear Implantation
Hearing LossUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence of treatment-emergent adverse events (Safety and Tolerability) of FX-322.
Treatment-emergent adverse events will be assessed over a several hour to two week period

To assess the incidence of adverse safety events (vertigo, tinnitus, perforation) including severe adverse events.

Secondary Endpoints

Plasma Pharmacokinetics
Systemic exposure will be evaluated over a 72 hour period
Cochlear Perilymph Pharmacokinetics
within a 24 hour period after injection
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingSINGLE
ModelSINGLE_GROUP
PurposeOTHER

Treatment Arms

ArmTypeDescription
ActiveACTIVE_COMPARATORSubjects will receive FX-322 as an intratympanic injection
PlaceboPLACEBO_COMPARATORSubjects will receive Placebo as an intratympanic injection

Interventions

NameTypeDescription
FX-322DRUGintratympanic injection
PlaceboDRUGintratympanic injection
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Male or female adult subjects with an established diagnosis of severe to profound sensorineural hearing loss audiometric threshold of 80 dB HL or poorer at 500 Hz that meets the criteria for cochlear implantation and the subject has already chosen to undergo cochlear implant ...

Countries:Australia
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Competitive Landscape -Hearing Loss 3 trials

Frequently asked questions about FX-322

What is FX-322 used for?

FX-322 is an investigational small molecule being developed for hearing loss. It is administered to adults undergoing cochlear implantation. The drug is in early clinical development, with a completed Phase 1 trial, and is not yet approved by regulatory authorities.

Who makes FX-322?

FX-322 is being developed by cbdMD, Inc., a company traded on the NYSE American under the ticker YCBD. The drug is in Phase 1 clinical development for hearing loss.

What phase is FX-322 in?

FX-322 is in Phase 1 clinical development. A first-in-human safety study has been completed, and the drug remains investigational. It has not been approved by the FDA or any other regulatory agency.

What clinical trials is FX-322 in?

FX-322 has one completed clinical trial, NCT03300687, titled "First in Human Safety Study of FX-322 in Adults Undergoing Cochlear Implantation." This early Phase 1 study enrolled 9 participants in Australia and was placebo-controlled.

Is FX-322 the same as cbdMD?

No, FX-322 is not the same as cbdMD. FX-322 is an investigational drug candidate for hearing loss, while cbdMD, Inc. is the company developing it. The company's stock trades under the ticker YCBD.