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Ondansetron

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment56

FDA Designations

No designations recorded

Clinical trial landscape

Ondansetron · 2 trials · 1 indication

Phase 1 2
NCT00648583Food Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mgHealthy
COMPLETED28 Analytics
NCT00649532Fasting Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mgHealthy
COMPLETED28 Analytics
PHASE1COMPLETED
Food Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mg
HealthyUnlock trial analytics
PHASE1COMPLETED
Fasting Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mg
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
1EXPERIMENTALOndansetron Tablets 24 mg
2ACTIVE_COMPARATORZofran® Tablets 24 mg

Interventions

NameTypeDescription
Ondansetron Tablets 24 mgDRUG24mg, single dose fed
Zofran® Tablets 24 mgDRUG24mg, single dose fed
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male or non-pregnant, non-lactating female 1. Women of childbearing potential must have negative serum (Beta HCG) pregnancy tests performed within 14 days prior to the start of the study and on the evening prior to each dose administration...

Countries:United States
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Frequently asked questions about Ondansetron

What is Ondansetron used for?

Ondansetron is a small molecule being developed by Viatris Inc. (VTRS). It is currently in Phase 1 clinical development, studied in healthy volunteers. The drug is being evaluated in clinical trials to assess its pharmacokinetics and bioequivalence compared to a reference product.

Who makes Ondansetron?

Ondansetron is being developed by Viatris Inc., a pharmaceutical company traded on the NASDAQ under the ticker symbol VTRS. The company is conducting Phase 1 clinical trials to evaluate the drug in healthy volunteers.

What phase is Ondansetron in?

Ondansetron is in Phase 1 clinical development. It is an investigational drug, not yet approved by regulatory authorities. Two Phase 1 trials have been completed, both involving healthy volunteers.

What clinical trials is Ondansetron in?

Ondansetron has completed two Phase 1 clinical trials. NCT00648583 is a food study of Ondansetron tablets 24 mg compared to Zofran tablets 24 mg. NCT00649532 is a fasting study of the same products. Both trials enrolled 28 healthy participants each in the United States.

Is Ondansetron the same as Zofran?

Ondansetron is being studied as a generic version of Zofran. The clinical trials compare Ondansetron tablets 24 mg to Zofran tablets 24 mg to evaluate bioequivalence under fed and fasting conditions.