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BALSALAZIDE DISODIUM

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment140

FDA Designations

No designations recorded

Clinical trial landscape

BALSALAZIDE DISODIUM · 2 trials · 1 indication

Phase 1 2
NCT00649480Fed Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mgHealthy
COMPLETED60 Analytics
NCT00648531Fasting Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mgHealthy
COMPLETED80 Analytics
PHASE1COMPLETED
Fed Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mg
HealthyUnlock trial analytics
PHASE1COMPLETED
Fasting Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mg
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
1EXPERIMENTALBALSALAZIDE DISODIUM CAPSULES, 750 MG
2ACTIVE_COMPARATORCOLAZAL® Capsules 750 mg

Interventions

NameTypeDescription
BALSALAZIDE DISODIUM CAPSULES, 750 MGDRUG3x750mg, single dose fed
COLAZAL® Capsules 750 mgDRUG3x750mg, single dose fed
Balsalazide Disodium Capsules 750 mgDRUG3x750mg, single dose fasting
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Age:18 years and older * Sex: Male and/or non-pregnant, non-lactating female * Women of childbearing potential had a negative serum beta human chorionic gonadotropin (β-HCG) pregnancy test performed within 21 days prior to the start of the study and on the evening prior to eac...

Countries:United States
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Frequently asked questions about BALSALAZIDE DISODIUM

What is BALSALAZIDE DISODIUM used for?

BALSALAZIDE DISODIUM is an investigational small molecule being studied in healthy volunteers. It is currently in Phase 1 clinical development, with completed trials evaluating its pharmacokinetics under fasting and fed conditions. The drug is being developed by Viatris Inc. (VTRS) and is not yet approved for any indication.

Who makes BALSALAZIDE DISODIUM?

BALSALAZIDE DISODIUM is being developed by Viatris Inc., a global healthcare company traded on the NASDAQ under the ticker VTRS. The company is conducting Phase 1 clinical trials to evaluate the drug's pharmacokinetic profile in healthy subjects.

What phase is BALSALAZIDE DISODIUM in?

BALSALAZIDE DISODIUM is in Phase 1 clinical development. Two Phase 1 studies have been completed, both involving healthy volunteers. The drug remains investigational and has not received FDA approval. Further clinical development phases have not been publicly disclosed.

What clinical trials is BALSALAZIDE DISODIUM in?

BALSALAZIDE DISODIUM has two completed Phase 1 trials: NCT00648531, a fasting study comparing the drug to Colazal capsules in 80 healthy subjects, and NCT00649480, a fed study in 60 healthy subjects. Both trials were conducted in the United States with participants aged 18 years and older.

Is BALSALAZIDE DISODIUM the same as Colazal?

BALSALAZIDE DISODIUM is being studied as a potential generic equivalent to Colazal, a brand-name drug. The Phase 1 trials were designed to compare the pharmacokinetics of Balsalazide Disodium Capsules 750 mg with Colazal Capsules 750 mg under fasting and fed conditions.