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Vor Biopharma Inc.

VOR
Biotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$19.9
▲ +0.77 · +4.03%

Financials

Last updated
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52W LOW $6.5052W HIGH $33.50
Volume
1.10 M
Value Traded
14.04 M
Short % Float
24.37%
+7.1%Week
-10.92%1 Month
+10.37%3 Month
+24.61%6 Month
-96.75%5 Year
-98.29%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
1.18 B
EPS (TTM)
-21.45
P/E Ratio
-
Ent. Value
711.20 M
Total Shares
59.16 M
Float Shares
32.43 M
Insiders
45.18%
Institutions
62.60%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 topline data readout
telitacicept
generalized myasthenia gravis (gMG)
Phase 3BiologicsNervous System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

VOR Catalyst Timeline

Dated clinical, regulatory and corporate events for Vor Biopharma Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Vor Biopharma Inc.

315Total events
8Upcoming
62Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T1Topline Readout
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TelitaciceptApproved
T2Quarterly Update
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Event history 50

▲Oral PresentationTelitaciceptApprovedPresentation
Telitacicept 48-week post hoc analysis presented at 2026 AANEM Annual Meeting MGFA Scientific Session
generalized myasthenia gravissource ↗
▲Additional DataTelitaciceptApprovedClinical Data
Post hoc 48-week analysis: 42% achieved MSE, 86.7% of MSE events sustained, >94% achieved ≥5-point MG-ADL improvement
generalized myasthenia gravissource ↗
▲Enrollment CompleteTelitaciceptApprovedTrial
Vor Bio completes enrollment in global Phase 3 UPSTREAM MG trial of telitacicept in gMG
generalized myasthenia gravissource ↗
●Enrollment UpdateTelitaciceptApprovedTrial
Enrollment ongoing for Phase 3 UPSTREAM SjD trial
primary Sjögren’s diseasesource ↗
●Quarterly UpdateCorporate
Q2 2026 financial results reported
●Runway Guidance UpdateCorporate
Pro-forma cash and investment balance of $514.5 million
▲NMPA NDA ApprovalTelitaciceptApprovedEx-US Regulatory
NMPA conditional approval for IgA nephropathy
IgA nephropathysource ↗
▲Primary Endpoint MetTelitaciceptApprovedClinical Data
Phase 3 TELIGAN met primary endpoint
IgA nephropathysource ↗
▲PublicationTelitaciceptApprovedPresentation
TELIGAN results published in New England Journal of Medicine
IgA nephropathysource ↗
◆Oral PresentationPresentation
Corporate update at Jefferies Global Healthcare Conference
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How VOR actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-11-08Telitacicept Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D29 / 100
Pipeline Score
$0M
Pipeline Value
Not rated
Valuation Signal
1
Drugs Scored
-
rNPV / MCap
Top 73%
Micro Cap
(rank 482 of 660)
Percentile Rank
Vor Biopharma Inc. faces pipeline headwinds (29/100), with 1 assets in development.
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Telitacicept Monoclonal antibodyNCT07404865Primary Sjogren's DiseasePhase 3 RECRUITING 250Jan 1, 2029
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Clinical Trial Results

Readouts, endpoints and source filings for every VOR program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
telitacicept generalized myasthenia gravisPhase 32026-09-2942%; 94%; ≥5-point MG-ADL improvement; 23.7%; 86.7%; 83-85%; 51%; 21%Read MoreTelitacicept Demonstrates Deep and Durable Minimal Symptom Expression Through 48 Weeks in Generalized Myasthenia GravisRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
RA CAPITAL MANAGEMENT, L.P.10% OwnerOption 500 500 held$12.80 10/02/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
TCG Crossover Management, LLC 2.5 % (-10.7 %) 104.44 M 5.67 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

VOR Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2027-01-15
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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How VOR ranks across every disease it competes in

Competitive Position is a premium feature
See how VOR ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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VOR News

VOR
Oct 5, 2026
VORGeneral

Vor Bio Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

Vor Bio has granted stock options and restricted stock units to nine new employees as part of its inducement plan under Nasdaq Listing Rule 5635(c)(4). The stock options, totaling 59,250 shares, have a ten-year term with an exercise price of $18.06. The RSUs represent 12,550 shares and both will vest over four years, contingent on continued employment.

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VOR
Sep 29, 2026
VORPhases

Telitacicept Demonstrates Deep and Durable Minimal Symptom Expression Through 48 Weeks in Generalized Myasthenia Gravis

Vor Bio announced positive results from a post hoc analysis of telitacicept in a Phase 3 trial for generalized myasthenia gravis. The study showed that 42% of participants achieved minimal symptom expression over 48 weeks, with a high rate of sustained responses. The findings were presented at the AANEM Annual Meeting, highlighting the potential of telitacicept to improve patient outcomes.

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VOR
Sep 8, 2026
VORPhases

Vor Completes Enrollment of Global Phase 3 UPSTREAM MG Trial and Expands Telitacicept Global Franchise into Ocular Myasthenia Gravis

Vor Bio has completed enrollment in its global Phase 3 trial, UPSTREAM MG, for telitacicept in generalized myasthenia gravis. The company plans to expand its development program into ocular myasthenia gravis with the initiation of UPSTREAM oMG, also expected to start in 2027. Topline results for the primary endpoint are anticipated in the first half of 2027.

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VOR
Sep 1, 2026
VORConferences/Events

Vor Bio To Participate in Upcoming September Conferences

Vor Bio announced its participation in several upcoming investor conferences in September 2026. The conferences include the Wells Fargo 21st Annual Healthcare Conference and the Citi Biopharma Back to School Conference, among others. These events will feature fireside chats and one-on-one meetings, providing opportunities for investor engagement.

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VOR
Aug 11, 2026
VORPhases

Vor Bio Reports Second Quarter 2026 Financial Results and Provides Corporate Update

Vor Bio has reported its second quarter 2026 financial results, highlighting that enrollment is on track for the Phase 3 UPSTREAM MG trial of telitacicept in generalized myasthenia gravis. Additionally, enrollment is ongoing for the Phase 3 UPSTREAM trial in primary Sjögren’s disease. The company also noted a robust cash and investment balance of $514.5 million.

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VOR
Jul 7, 2026
VORGeneral

Vor Bio Appoints David Zaccardelli to Board of Directors

Vor Bio has appointed David Zaccardelli to its Board of Directors, bringing over 20 years of biopharmaceutical leadership experience. His previous successes include leading Verona Pharma through significant growth and FDA approval. Zaccardelli's expertise is expected to aid Vor Bio in advancing telitacicept through global Phase 3 development for autoimmune diseases.

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VOR
Jun 8, 2026
VORFDA Updates

Telitacicept Receives NMPA Approval for the Treatment of Sjögren’s Disease in China

Vor Bio's telitacicept has received approval from China's NMPA for treating Sjögren's disease, marking it as the first therapy approved for this condition in the country. The approval is based on positive Phase 3 trial results demonstrating significant improvements in disease activity and patient-reported outcomes. This is the fifth indication for telitacicept, which is also being developed for other autoimmune diseases.

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VOR
Jun 8, 2026
VORFDA Updates

Telitacicept Receives NMPA Conditional Approval for the Treatment of IgA Nephropathy in China

Vor Bio's telitacicept has received conditional approval from China's NMPA for the treatment of IgA nephropathy (IgAN), marking it as the first approved BAFF/APRIL-targeting therapy for this condition. The approval is based on positive efficacy results from the Phase 3 TELIGAN trial, which showed significant reductions in urinary protein-to-creatinine ratio. Vor Bio maintains exclusive rights for global commercialization, while RemeGen is responsible for its development within China. This approval underscores the potential of telitacicept in addressing the underlying immunological aspects of IgAN and other autoimmune diseases.

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VOR
Jun 2, 2026
VORGeneral
▼ -6.2%on this news

Vor Bio Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) - June 1, 2026

Vor Bio has granted stock options and restricted stock units to 10 new employees as part of its inducement plan under Nasdaq Listing Rule 5635(c)(4). The stock options have a ten-year term with an exercise price equal to the closing price on the grant date. The vesting schedule for both stock options and RSUs spans four years, contingent on continued employment.

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VOR
May 28, 2026
VORConferences/Events

Vor Bio to Participate in the 2026 Jefferies Global Healthcare Conference

Vor Bio will participate in the 2026 Jefferies Global Healthcare Conference, providing a corporate update during a fireside chat. The presentation is scheduled for June 3, 2026, and will be accessible via a live webcast. Vor Bio is focused on advancing its telitacicept treatment for autoimmune diseases through Phase 3 clinical development.

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VOR
May 14, 2026
VORPhases
▼ -5.3%on this news

Vor Bio Announces Publication of Interim Analysis of TELIGAN, a China Phase 3 Trial of Telitacicept in IgA Nephropathy, in The New England Journal of Medicine

Vor Bio has announced positive interim analysis results from the Phase 3 TELIGAN trial of telitacicept, published in The New England Journal of Medicine. The study reported a significant 55% relative reduction in proteinuria and stable kidney function after 39 weeks of treatment compared to placebo. The results suggest the potential of telitacicept as a leading therapy for IgA nephropathy and other autoimmune diseases. The therapy is currently undergoing regulatory evaluations and might be positioned as a best-in-class dual BAFF/APRIL treatment.

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VOR
May 13, 2026
VORPhases

Vor Bio Reports First Quarter 2026 Financial Results and Provides Corporate Update

Vor Bio reported its financial results for Q1 2026, highlighting ongoing enrollment in Phase 3 trials for telitacicept in generalized myasthenia gravis and primary Sjögren’s disease. The company maintains a strong cash position of $491.5 million, expected to support operations until early 2029. Despite an increased net loss, the company is optimistic about the potential of telitacicept as a foundational therapy in autoimmune diseases.

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VOR
Mar 30, 2026
VORPhases

Vor Bio Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

Vor Bio has reported its financial results for Q4 and full year 2025, highlighting the initiation of a global Phase 3 trial for telitacicept in primary Sjögren's disease. The company secured a $75 million private placement to support its clinical development efforts. Despite a significant net loss for the year, Vor Bio maintains a strong cash position, expected to fund operations into early 2029.

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VOR
Mar 30, 2026
VORPhases

Vor Bio Doses First Patient in Global Phase 3 UPSTREAM SjD Registrational Trial of Telitacicept in Primary Sjögren’s Disease

Vor Bio has initiated the Phase 3 UPSTREAM SjD trial by dosing the first patient with telitacicept for primary Sjögren’s disease. This trial aims to evaluate the efficacy and safety of telitacicept, a unique BAFF/APRIL inhibitor, in a patient population that currently lacks approved disease-modifying therapies. The trial will involve approximately 250 patients and assess key disease activity metrics.

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VOR
Mar 27, 2026
VORGeneral
▲ +6.7%on this news· ran to +28% by day 3shared move

Vor Bio Announces $75 Million Private Placement with TCGX

Vor Bio has announced a $75 million private placement to fund the clinical development of telitacicept, a treatment for autoimmune diseases. The financing, led by TCGX, will support ongoing Phase 3 trials for generalized myasthenia gravis and primary Sjögren's disease. The private placement is expected to close around March 30, 2026.

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About Vor Biopharma Inc.

Boston, MA 76 employees vorbio.com
Headquarters500 BOYLSTON STREET, BOSTON, MA, 02116
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