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cP12

Phase 2

Thermal Burns | Small molecule | Dermatology |United Therapeutics Corporation|Last Updated: Feb 18, 2026

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment6

FDA Designations

No designations recorded

Clinical trial landscape

cP12 · 1 trial · 1 indication

Phase 2 1
NCT06814717A Safety, Tolerability and Pharmacokinetic Study of cP12 in Adults With Up To 10% Total Body Surface Area BurnsThermal Burns
RECRUITING6 Analytics
PHASE2RECRUITING
A Safety, Tolerability and Pharmacokinetic Study of cP12 in Adults With Up To 10% Total Body Surface Area Burns
Thermal BurnsUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence and severity of adverse events from dosing through follow-up
Day 1, Day 3 and Day 14

Clinical safety labs will be collected

Secondary Endpoints

Investigate pharmacokinetic profile
Predose, 2,5,15,30,60,120 and 240 minutes post dose
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeOTHER

Treatment Arms

ArmTypeDescription
Open-labelEXPERIMENTALSix adult male or female subjects will receive a single administration of 0.01mg/kg of cP12.

Interventions

NameTypeDescription
cP12DRUGcP12 is a novel fibronectin derived, 14-mer peptide
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * BMI between 18 kg/m2 (inclusive) and body weight \>/=50kg * TBSA thermal burns up to and including 10%. The selected burn must be superficial (epidermal), superficial partial-thickness, or deep partial-thickness * Able to be infused with cP12 within 2 to 24 hours post burn * A...

Countries:United States
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Frequently asked questions about cP12

What is cP12 used for?

cP12 is an investigational small molecule being developed for the treatment of thermal burns. It is currently in Phase 2 clinical development and is not yet approved by the FDA.

Who makes cP12?

cP12 is being developed by United Therapeutics Corporation, a company traded on the NASDAQ under the ticker symbol UTHR.

What phase is cP12 in?

cP12 is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA. A Phase 2 trial is currently recruiting participants in the United States.

What clinical trials is cP12 in?

cP12 is being studied in a Phase 2 clinical trial with the identifier NCT06814717. This trial is titled 'A Safety, Tolerability and Pharmacokinetic Study of cP12 in Adults With Up To 10% Total Body Surface Area Burns' and is currently recruiting participants.

Is cP12 being studied in a randomized controlled trial?

No, the Phase 2 clinical trial of cP12 is not randomized and does not use a control group. It is an uncontrolled study that is also not double-blinded. The trial is designed to assess safety, tolerability, and pharmacokinetics.