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UI05MSP015CT

Phase 3

Functional Dyspepsia | Small molecule | Gastrointestinal |United Therapeutics Corporation|Last Updated: Jul 21, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindACTIVE_CONTROLLEDBiomarker
Total Trials1
Total Enrollment143

FDA Designations

No designations recorded

Clinical trial landscape

UI05MSP015CT · 1 trial · 1 indication

Phase 3 1
NCT03225248Efficacy and Safety of UI05MSP015CT in Functional DyspepsiaFunctional Dyspepsia
COMPLETED143 Analytics
PHASE3COMPLETED
Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia
Functional DyspepsiaUnlock trial analytics

Study Endpoints

Primary Endpoints

Change of symptom score of functional dyspepsia
4weeks

Change of symptom score of functional dyspepsia was evaluated by symptom-specific questionnaire.

Secondary Endpoints

Change of symptom score of functional dyspepsia
2weeks
General symptom improvement
2weeks, 4weeks
NDI-K questionnaire
4weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
UI05MSP015CTEXPERIMENTALUI05MSP015CT and Placebo of Gasmotin
GasmotinACTIVE_COMPARATORPlacebo of UI05MSP015CT and Gasmotin

Interventions

NameTypeDescription
UI05MSP015CTDRUGUI05MSP015CT and Placebo of Gasmotin
GasmotinDRUGPlacebo of UI05MSP015CT and Gasmotin
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Eligibility Criteria

Age Range19 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: 1. Age \>19 years 2. Diagnosis of functional dyspepsia meeting Rome III criteria 3. At least three moderate or severe symptoms included in the Symptom Score 4. No structural lesions of upper gastrointestinal tract Exclusion Criteria: 1. History of dyspepsia unrelated to functi...

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Frequently asked questions about UI05MSP015CT

What is UI05MSP015CT used for?

UI05MSP015CT is an investigational small molecule being developed for the treatment of functional dyspepsia, a gastrointestinal condition. It is currently in Phase 3 clinical development. The drug has been studied in a completed Phase 3 trial that enrolled 143 participants.

Who makes UI05MSP015CT?

UI05MSP015CT is being developed by United Therapeutics Corporation, a biopharmaceutical company traded on the NASDAQ under the ticker symbol UTHR. The company is conducting clinical trials to evaluate the drug's efficacy and safety in patients with functional dyspepsia.

What phase is UI05MSP015CT in?

UI05MSP015CT is in Phase 3 clinical development for functional dyspepsia. A Phase 3 trial has been completed, with 143 participants enrolled. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is UI05MSP015CT in?

UI05MSP015CT has been studied in one completed Phase 3 clinical trial, identified as NCT03225248. This randomized, double-blind, active-controlled study evaluated the efficacy and safety of UI05MSP015CT in 143 participants with functional dyspepsia.

Is UI05MSP015CT FDA approved?

UI05MSP015CT is not FDA approved. It is an investigational drug currently in Phase 3 clinical development for functional dyspepsia. The completed Phase 3 trial, NCT03225248, has finished, but the drug has not received regulatory approval.