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Tectonic Therapeutic, Inc. Common Stock

$29.95

-0.11 (-0.37%)

D 32Pipeline Score Richly Valued Biotech · Clinical
Market Cap
576.82 M
EPS
-4.04
P/E Ratio
-7.6 $
Value Trade
3.71 M
SEC Financials
Q1 2026
  • Dilution Risk

    5%
  • R&D Expenses

    20.87 M

  • Operating CF

    -18.41 M


  • Total Assets

    246.58 M

  • Total Liabilities

    16.16 M

  • Equity

    230.42 M

  • D/E Ratio

    12,345

%
Week
%
1 Month
%
3 Month
%
6 Month
%
5 Year
%
All Time
Cash Data
Healthy
  • Cash Position

    236.89 M

  • Monthly Burn

    6.14 M

  • Runway

    37.2 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 7, 2026
Overview
Volume
50.31 K
52 Week Range
14.39 - 36.03
% held by Insiders
49.76 %
% held by Institutions
62.9 %
Enterprise Value
323.71 M
Total Shares
18.78 M
Short %
24.69 %
Float Shares
9.88 M
Company Description
HQ: 490 ARSENAL WAY, WATERTOWN, MA
Employees:60

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
TX2100 Hereditary Hemorrhagic Telangiectasia (HHT)
Phase 1a
Biologics
Rare Diseases
TX2100 Hereditary Hemorrhagic Telangiectasia (HHT)
Phase 1a
Biologics
Rare Diseases
TX2100 Hereditary Hemorrhagic Telangiectasia (HHT)
Phase 1a
Biologics
Rare Diseases
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Drug Pipeline Intelligence
D32
Pipeline Score
$60M
Pipeline Value
Richly Valued
Valuation Signal
1
Drugs Scored
0.1x
rNPV / MCap
Top 40%
Micro Cap
(rank 544 of 905)
Percentile Rank
Tectonic Therapeutic, Inc. Common Stock faces pipeline headwinds (32/100), with $151M risk-adjusted pipeline value, led by TX000045- Dose A in Pulmonary Hypertension (Phase 2).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
TX000045- Dose A
Small molecule
Pulmonary HypertensionPhase 2NCT066169749% $151M RECRUITING 180 STALLED D (25) Nov 1, 2026ELEVATED_RISKLOW
May 24, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
Example Drug
Example indication for clinical evaluation
Phase 3
2025-12-01
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
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Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
Biotech Analyst Ratings
Symbol
Firm
Rating
Action
Price Target
Upside
date
TECX
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
TECX
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
TECX
Example Securities
Buy
Initiated
$150.00
+25%
2026-01-15
Unlock Biotech Analyst Ratings data
TECX Stock Forecast & Analyst Consensus
BUY
Analyst Ratings
Buy65.0%
Hold25.0%
Sell10.0%
Price Target Trend
Average$24.00
Low$18.00
High$32.00
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TECX Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
2026-09-18 0.00 0 - - - - - -
2026-09-18 0.00 0 - - - - - -
2026-09-18 0.00 0 - - - - - -
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
-TECX
Jun 10, 2026
TECXPhases

Tectonic Therapeutic Completes Enrollment in TX45 APEX Phase 2 Clinical Trial in PH-HFpEF Patients

Tectonic Therapeutic has completed enrollment for its APEX Phase 2 clinical trial, which evaluates the safety and efficacy of TX45 in patients with pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF). The trial enrolled 191 patients across 14 countries, focusing on a severe subtype of the disease. Topline results are anticipated in early Q1 2027.

Read more →
-TECX
May 7, 2026
TECXPhases

Tectonic Therapeutic Announces First Quarter 2026 Financial Results and Recent Business Highlights

Tectonic Therapeutic reported its Q1 2026 financial results, highlighting significant progress in its clinical trials, including the nearing completion of patient enrollment for the TX45 APEX Phase 2 trial and the initiation of the TX2100 Phase 1a trial. The company appointed new board members to strengthen governance and reported a cash position of $236.9 million, expected to sustain operations through Q4 2028. However, the company also noted an increase in net loss and R&D expenses compared to the previous year.

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-TECX
Apr 23, 2026
TECXGeneral

Tectonic Therapeutic Appoints Jessica Chutter to Board of Directors

Tectonic Therapeutic has appointed Jessica Chutter to its Board of Directors, effective June 8, 2026. Chutter, a veteran in healthcare investment banking, is expected to leverage her extensive experience to support Tectonic's strategic initiatives and growth. The company is progressing towards becoming a multi-product clinical entity with a promising pipeline.

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-TECX
Mar 2, 2026
TECXConferences/Events

Tectonic Therapeutic to Participate in March Investor Conferences

Tectonic Therapeutic, a clinical-stage biotech firm, will participate in two investor conferences in March 2026. The company's management will host one-on-one meetings and fireside chats, which will be accessible on their website. Tectonic is focused on developing therapeutic proteins and antibodies targeting GPCRs to address unmet medical needs.

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-TECX
Feb 24, 2026
TECXGeneral

Tectonic Therapeutic Appoints François Nader, M.D., as Chair and Independent Director of the Board

Tectonic Therapeutic has appointed Dr. François Nader as Chair and Independent Director of its Board, effective April 1, 2026. Dr. Nader, who has over 30 years of experience in biotechnology, will succeed Terry McGuire, who will remain on the board until the 2026 Annual Meeting. This leadership change is expected to enhance Tectonic's strategic direction and growth in GPCR-targeted therapies.

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-TECX
Feb 12, 2026
TECXConferences/Events

Tectonic Therapeutic to Host Virtual KOL Event and Discussion of TX2100, a Novel Approach for the Treatment of Hereditary Hemorrhagic Telangiectasia, on February 24, 2026

Tectonic Therapeutic is set to host a virtual KOL event on February 24, 2026, to discuss TX2100, a novel GPCR antagonist for treating Hereditary Hemorrhagic Telangiectasia (HHT). The event will feature Dr. Hanny Al-Samkari, who will provide insights into HHT's clinical context and the preclinical evidence supporting TX2100. Tectonic plans to initiate a Phase 1a trial of TX2100 in early 2026.

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Competitive Position
How TECX ranks across every disease it competes in
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