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SYNB1020

Phase 1

Healthy Volunteer | Small molecule | Rare Disease |Synlogic, Inc.|Last Updated: May 12, 2021

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment52

FDA Designations

No designations recorded

Clinical trial landscape

SYNB1020 · 1 trial · 2 indications

Phase 1 1
NCT03179878Safety and Tolerability of SYNB1020-CP-001Healthy Volunteer
COMPLETED52 Analytics
PHASE1COMPLETED
Safety and Tolerability of SYNB1020-CP-001
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Study Endpoints

Primary Endpoints

Incidence of Treatment-Emergent Adverse Events, Laboratory Assessments and ECGs to measure Safety and Tolerability of SYNB1020
3 months from study entry

Will be measured by assessing nature and frequency of AEs, Laboratory Assessments, and ECGs

Secondary Endpoints

GI tolerability measured using the Gastrointestinal Symptom Rating Scale (GSRS)
1 month of study entry
SYNB1020 kinetics measured by qPCR fecal assays
3 months from study entry
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
SYNB1020EXPERIMENTALSYNB1020
PlaceboPLACEBO_COMPARATOR100 mL masking solution

Interventions

NameTypeDescription
PlaceboDRUGPlacebo
SYNB1020DRUGInvestigational Product
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Eligibility Criteria

Age Range18 Years to 64 Years
SexALL
Healthy VolunteersYes
Study Sites1

Key Inclusion Criteria: * Age 18 to 64 years * Healthy volunteer Males and Females; Females must be of non childbearing potential * Able and willing to complete informed consent process * Available for and agree to all study procedures * Screening Labs within normal range Key Exclusion Criteria: ...

Countries:United States
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Frequently asked questions about SYNB1020

What is SYNB1020 used for?

SYNB1020 is an investigational drug being studied for use in healthy volunteers and for urea cycle disorder. It is a small molecule being developed by Synlogic, Inc. As of now, it is in Phase 1 clinical development and is not approved by the FDA.

Who makes SYNB1020?

SYNB1020 is being developed by Synlogic, Inc., a biopharmaceutical company. The company's ticker symbol is SYBX. The drug is currently in Phase 1 clinical trials and is not yet approved for commercial use.

What phase is SYNB1020 in?

SYNB1020 is in Phase 1 clinical development. It is an investigational drug, meaning it has not been approved by the FDA. The drug is being studied for safety and tolerability in healthy volunteers and for urea cycle disorder.

What clinical trials is SYNB1020 in?

SYNB1020 has one completed Phase 1 clinical trial with the identifier NCT03179878. The trial, titled 'Safety and Tolerability of SYNB1020-CP-001', enrolled 52 participants in the United States. It was a randomized, double-blind, placebo-controlled study involving healthy volunteers.

Is SYNB1020 FDA approved?

No, SYNB1020 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development. The drug is being studied for safety and tolerability, and it has not yet completed the clinical trials required for regulatory approval.