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Synlogic, Inc.

SYBXFDA catalysts, PDUFA dates & pipeline intelligence
$1.21
▲ +0.04 · +7.27%

Financials

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R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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52W LOW $0.5652W HIGH $1.96
Volume
482.00
Value Traded
579.60
Short % Float
0.05%
Days to Cover
1.0
-50.88%Week
-52.14%1 Month
-67.91%3 Month
-65.54%6 Month
-99.03%5 Year
-99.93%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
6.55 M
EPS (TTM)
-0.27
P/E Ratio
-
Ent. Value
-9.04 M
Total Shares
11.71 M
Float Shares
7.04 M
Insiders
39.35%
Institutions
37.16%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

SYBX Catalyst Timeline

Dated clinical, regulatory and corporate events for Synlogic, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How SYBX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
5
Drugs Scored
rNPV / MCap
Top Drug
Showing 5 of 6 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
SYNB1618 Small moleculeCompletedNCT03516487PhenylketonuriaPhase 2 COMPLETED 90Jun 21, 2019
SYNB1934 Small moleculeCompletedNCT04984525PhenylketonuriaPhase 1 COMPLETED 106Dec 10, 2021
SYNB8802v1 Small moleculeCompletedNCT05377112Enteric HyperoxaluriaPhase 1 COMPLETED 11Dec 7, 2022
SYNB8802 Small moleculeCompletedNCT04629170Enteric HyperoxaluriaPhase 1 COMPLETED 77Jan 17, 2023
SYNB1353 Small moleculeCompletedNCT05462132HomocystinuriaPhase 1 COMPLETED 31Nov 27, 2022
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every SYBX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
SYNB8802 Enteric HyperoxaluriaPhase 1b2022-12-15-38% reduction in urinary oxalate compared to placebo; -28% (-37.2, -18.2) change from baseline in urinary oxalate vs. placebo at the 1x1011 TID dose; -38% (-46.4, -28.7) change from baseline in urinary oxalate vs. placebo at the 3x1011 TID doseRead MoreSynlogic Announces Achievement of Proof of Concept for SYNB8802 in Enteric Hyperoxaluria Based on Urinary Oxalate Lowering in Phase 1b Study Results include -38% reduction in urinary oxalate compared to placebo in Roux-eRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
New Enterprise Associates 14, L.P.10% OwnerBuyWarrant exercise 2,640,845 2,640,845 held$0.00 07/27/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
NEA Management Company, LLC 0.2 % (-33.3 %) 3.27 M 2.92 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

SYBX Short Interest

Shares sold short, counted twice a month.

0.05%
Short % of Float
of tradable shares sold short
2.9K
Shares Sold Short
-0.7% vs prior count
1.0 Low
Days to Cover
trading days of normal volume to buy every short share back
89.8K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How SYBX ranks across every disease it competes in

Competitive Position is a premium feature
See how SYBX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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SYBX News

About Synlogic, Inc.

Headquarters301 Binney Street
Founded30-09-2015
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