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AVI-4020

Phase 1

West Nile Virus | Small molecule | Infectious Disease |Sarepta Therapeutics, Inc.|Last Updated: Jul 8, 2009

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment14

FDA Designations

No designations recorded

Clinical trial landscape

AVI-4020 · 1 trial · 1 indication

Phase 1 1
NCT00387283Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020West Nile Virus
COMPLETED14 Analytics
PHASE1COMPLETED
Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020
West Nile VirusUnlock trial analytics

Study Endpoints

Primary Endpoints

To determine if the study drug penetrates the blood brain barrier following a single dose of AVI-4020, and if it does, the associated CSF, plasma and urine pharmacokinetics

Secondary Endpoints

Safety, Tolerability
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
AVI-4020 InjectionDRUG -
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Eligibility Criteria

Age Range18 Years to 64 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Adult males 18 years to 64 years of age; * Good general health (as evidenced by no chronic conditions, normal physical exam, vital signs within normal limits; laboratory evaluations within normal range) * Signed and dated written informed consent form; and * Willing to partici...

Countries:United States
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Frequently asked questions about AVI-4020

What is AVI-4020 used for?

AVI-4020 is an investigational small molecule being developed for West Nile Virus. It is currently in Phase 1 clinical development, meaning it has not been approved and is still being studied for safety and pharmacokinetics in humans.

Who makes AVI-4020?

AVI-4020 is being developed by Sarepta Therapeutics, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker SRPT. The company is conducting clinical research on this drug candidate for West Nile Virus.

What phase is AVI-4020 in?

AVI-4020 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The Phase 1 trial has been completed, and the drug remains in early-stage clinical research.

What clinical trials has AVI-4020 been in?

AVI-4020 has been studied in one completed Phase 1 clinical trial, NCT00387283, titled "Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020." The trial enrolled 14 healthy male volunteers aged 18 years and older in the United States.

Is AVI-4020 the same as any other drug?

AVI-4020 is the primary name for this investigational drug candidate. No alternative names have been reported for this compound in clinical development.