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ITP FIRTECH

Phase 3

Low Back Pain | Unknown | Pain |Sanofi|Last Updated: Sep 9, 2025

Success Probability

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Market & Valuation

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Trial Design

RandomizedNO_TREATMENT_CONTROLLED
Total Trials1
Total Enrollment221

FDA Designations

No designations recorded

Clinical trial landscape

ITP FIRTECH · 1 trial · 1 indication

Phase 3 1
NCT05137041Efficacy and Safety of FIRTECH in Patients With Mild to Moderate Acute Low Back PainLow Back Pain
COMPLETED221 Analytics
PHASE3COMPLETED
Efficacy and Safety of FIRTECH in Patients With Mild to Moderate Acute Low Back Pain
Low Back PainUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Numerical Rating Scale (NRS) Responders at Day 5
Day 5

NRS is used to assess pain intensity, it is a 11-point scale (0-10) where '0' representing 'no pain' and '10' representing 'worst pain imaginable'. Responder is defined as participant with ≥30% decrease from baseline in pain NRS and who did not take rescue medication (defined as receiving paracetamol (authorized), any other analgesics and anti-inflammatory drugs as well as any non-pharmaceutical therapy (prohibited) for treating pain starting from randomization to Day 5 or starting before the study and still ongoing at randomization).

Secondary Endpoints

Number of Participants Reported With Treatment Emergent Adverse Events (TEAEs)
Day 1 to Day 6
Normalized Sum of Pain Intensity Difference (PID) Over 5 Days (SPID0-5)
Baseline, Day 5
Percentage Change in Roland-Morris Disability Questionnaire (RMDQ) Score
From Baseline to Day 5
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
ITP FIRTECHEXPERIMENTALThe ITP FIRTECH patch was applied on the lower back region of the body on Day 1 and intended to be worn for 5 Days (Day 5).
No Patch Control ArmNO_INTERVENTIONNo patch application.

Interventions

NameTypeDescription
ITP FIRTECHDEVICEInfrared Therapy Patch
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites7

Inclusion Criteria: * Participants suffering from mild to moderate acute low back pain * Low back pain (lumbar back pain) is defined as pain in the back from the level of the lowest rib down to the gluteal fold * Acute episode is defined as acute pain with less than 1 month duration * With intensit...

Countries:GermanyItaly
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Frequently asked questions about ITP FIRTECH

What is ITP FIRTECH used for?

ITP FIRTECH is an investigational drug being studied for the treatment of mild to moderate acute low back pain. It is currently in Phase 3 clinical development and has not been approved by regulatory authorities.

Who makes ITP FIRTECH?

ITP FIRTECH is being developed by Sanofi, a multinational pharmaceutical company listed on the stock exchange under the ticker symbol SNY.

What phase is ITP FIRTECH in?

ITP FIRTECH is in Phase 3 clinical development. It is an investigational drug and has not yet been approved for use. A Phase 3 trial has been completed to evaluate its efficacy and safety in patients with low back pain.

What clinical trials is ITP FIRTECH in?

ITP FIRTECH has one completed Phase 3 clinical trial registered as NCT05137041, titled 'Efficacy and Safety of FIRTECH in Patients With Mild to Moderate Acute Low Back Pain.' The trial enrolled 221 participants in Germany and Italy and was not double-blinded.

Is ITP FIRTECH the same as FIRTECH?

Yes, ITP FIRTECH is also known as FIRTECH. The clinical trial NCT05137041 refers to the drug as FIRTECH, and both names refer to the same investigational product being developed by Sanofi for low back pain.