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HBVaxPRO 5 µg

Phase 3

Hepatitis B | Monoclonal antibody | Infectious Disease |Sanofi|Last Updated: Sep 11, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment410

FDA Designations

No designations recorded

Clinical trial landscape

HBVaxPRO 5 µg · 1 trial · 1 indication

Phase 3 1
NCT00693186A Study to Assess the Anamnestic Immune Response in Healthy 4 to 7 Year-old Children After a Primary Vaccination Series With Either HEXAVAC® or INFANRIX®-HEXAHepatitis B
COMPLETED410 Analytics
PHASE3COMPLETED
A Study to Assess the Anamnestic Immune Response in Healthy 4 to 7 Year-old Children After a Primary Vaccination Series With Either HEXAVAC® or INFANRIX®-HEXA
Hepatitis BUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of subjects with anti-HBs antibody titres >=10 mIU/mL measured at 1 month post-booster dose
28 to 42 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -
2EXPERIMENTAL -

Interventions

NameTypeDescription
HBVaxPRO® 5 µg / 0.5 mLBIOLOGICAL5 µg / 0.5 mL
Engerix B® 10 µg / 0.5 mLBIOLOGICAL10 µg
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Eligibility Criteria

Age Range4 Years to 7 Years
SexALL
Healthy VolunteersYes
Study Sites5

Inclusion Criteria: * Healthy child of 4 to 7 years of age of either gender, * Child vaccinated with 2 doses of HEXAVAC® during the first 6 months of life and with a 3rd dose of HEXAVAC® before the end of the second year of life or Child vaccinated with 2 doses of INFANRIX®-HEXA during the first 6 ...

Countries:Italy
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Frequently asked questions about HBVaxPRO 5 µg

What is HBVAXPRO 5µg used for?

HBVAXPRO 5µg is a vaccine used for Hepatitis B and virus diseases. It is being developed by Sanofi for the prevention of Hepatitis B infection. The vaccine is currently in Phase 3 clinical development and is intended for use in healthy children to assess immune response after primary vaccination.

Who makes HBVAXPRO 5µg?

HBVAXPRO 5µg is developed by Sanofi, a multinational pharmaceutical company listed on the stock exchange under the ticker SNY. Sanofi is conducting clinical trials to evaluate the vaccine's immunogenicity and safety in pediatric populations.

What phase is HBVAXPRO 5µg in?

HBVAXPRO 5µg is in Phase 3 clinical development. It is an investigational vaccine, meaning it has not yet been approved by regulatory authorities. The Phase 3 trials are completed and focused on assessing immune responses in healthy children.

What clinical trials is HBVAXPRO 5µg in?

HBVAXPRO 5µg has been studied in two completed Phase 3 trials. NCT00693186 assessed anamnestic immune response in children aged 4 to 7 years after primary vaccination with HEXAVAC or INFANRIX-HEXA. NCT02012998 evaluated immunogenicity and safety of a challenge dose in children vaccinated 10 years earlier.

Is HBVAXPRO 5µg the same as HEXAVAC or INFANRIX-HEXA?

No, HBVAXPRO 5µg is not the same as HEXAVAC or INFANRIX-HEXA. HBVAXPRO is a separate vaccine developed by Sanofi. The clinical trials compare immune responses in children who received primary vaccination with HEXAVAC or INFANRIX-HEXA, followed by a challenge dose of HBVAXPRO.