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Euvax B: Hepatitis B vaccine

Phase 3

Hepatitis B | Monoclonal antibody | Infectious Disease |Sanofi|Last Updated: Apr 6, 2022

Success Probability

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Market & Valuation

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Trial Design

CONTROLLED
Total Trials1
Total Enrollment150

FDA Designations

No designations recorded

Clinical trial landscape

Euvax B: Hepatitis B vaccine · 1 trial · 1 indication

Phase 3 1
NCT02697474Anti-Hep B Antibodies at Age 9 to 10 Years After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine.Hepatitis B
COMPLETED150 Analytics
PHASE3COMPLETED
Anti-Hep B Antibodies at Age 9 to 10 Years After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine.
Hepatitis BUnlock trial analytics

Study Endpoints

Primary Endpoints

Levels of anti-Hepatitis B antibody concentrations in subject that received Hexaxim® or Infanrix® hexa vaccine in a previous study
Day 0 (pre-vaccination)
Levels of anti-Hepatitis B antibody concentrations in subject that received Hexaxim® or Infanrix® hexa vaccine in a previous study following vaccination with Euvax B® vaccine
Day 28 (post-vaccination)

Secondary Endpoints

Number of subjects reporting Serious Adverse Events and relatedness to study vaccine throughout the study
Day 0 up to Day 28 post-vaccination
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Hexaxim® GroupEXPERIMENTALSubjects that received Hexaxim® in Study A3L12
Infanrix® hexa GroupEXPERIMENTALSubjects that received Infanrix® hexa in Study A3L12

Interventions

NameTypeDescription
Euvax B®: Hepatitis B vaccineBIOLOGICAL0.5 mL, Intramuscular
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Eligibility Criteria

Age Range9 Years to 10 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Informed consent form signed by subject's parent/legally acceptable representative * Assent form signed by subject * Subject and parent(s)/legally acceptable representatives able to attend the scheduled visits and to comply with all trial procedures * Receipt of primary vaccin...

Countries:Thailand
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Frequently asked questions about Euvax B: Hepatitis B vaccine

What is Euvax B used for?

Euvax B is a hepatitis B vaccine used for the prevention of hepatitis B infection. It is indicated for hepatitis B, an infectious disease affecting the liver. The vaccine is designed to generate an immune response against the hepatitis B virus.

Who makes Euvax B?

Euvax B is developed by Sanofi, a multinational pharmaceutical company traded on the stock exchange under the ticker symbol SNY. Sanofi is responsible for the development and clinical testing of this hepatitis B vaccine.

What phase is Euvax B in?

Euvax B is in Phase 3 clinical development. It is an investigational hepatitis B vaccine, meaning it has not yet been approved by regulatory authorities and is still undergoing clinical trials to evaluate its safety and efficacy.

What clinical trials is Euvax B in?

Euvax B has one completed Phase 3 clinical trial registered under NCT02697474. This trial, conducted in Thailand, enrolled 150 participants aged 9 to 10 years to assess anti-hepatitis B antibodies following vaccination at birth and with a hexavalent vaccine.

Is Euvax B a monoclonal antibody?

Euvax B is classified as a monoclonal antibody modality, though it functions as a vaccine. In the context of the clinical trial data, it is described as a hepatitis B vaccine, and its mechanism involves eliciting an immune response against the hepatitis B virus.