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SpyGlass Pharma, Inc.

$22.52

+2.45 (+12.21%)

D 34Pipeline Score Overvalued Biotech · Clinical
Market Cap
696.75 M
EPS
-
P/E Ratio
-
Value Trade
877.00 K
SEC Financials
Q1 2026
  • Dilution Risk

    5%
  • R&D Expenses

    8.54 M

  • Operating CF

    -13.54 M


  • Total Assets

    258.39 M

  • Total Liabilities

    8.27 M

  • Equity

    250.11 M

  • D/E Ratio

    12,345

-4.84 %
Week
-15.8 %
1 Month
-29.74 %
3 Month
-17.47 %
6 Month
-17.47 %
5 Year
-17.47 %
All Time
Cash Data
Healthy
  • Cash Position

    238.90 M

  • Monthly Burn

    4.51 M

  • Runway

    51.2 mo

  • Burn Trend

    Accelerating
  • SEC Filing

    May 14, 2026
Overview
Volume
169.49 K
52 Week Range
20.15 - 30.56
% held by Insiders
58.27 %
% held by Institutions
38.29 %
Enterprise Value
447.36 M
Total Shares
33.33 M
Short %
22.1 %
Float Shares
5.93 M
Company Description
HQ: 27081 ALISO CREEK ROAD, ALISO ...
Employees:65

locked

Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
Example Drug Treatment for example condition requiring FDA review
Phase 3
-%

FDA review of the new drug application for the treatment of example condition.

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Small Molecule
Oncology
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Drug Pipeline Intelligence
D34
Pipeline Score
$290M
Pipeline Value
Overvalued
Valuation Signal
2
Drugs Scored
0.4x
rNPV / MCap
Top 44%
Micro Cap
(rank 511 of 911)
Percentile Rank
SpyGlass Pharma, Inc. faces pipeline headwinds (34/100), with $724M risk-adjusted pipeline value, led by Bimatoprost System in Cataract (Phase 3).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
Bimatoprost System
Small molecule
CataractPhase 3NCT0612084243% $665M ACTIVE NOT_RECRUITING 1,001 AVERAGE B (63) Nov 1, 2027LOW_RISKLOW
May 26, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
BIM-IOL System
open-angle glaucoma (OAG) or ocular hypertension (OHT)
Phase 1/2
2026-05-14

In the Phase 1/2 trial of the BIM-IOL System, 98% of participants were free from topical IOP-lowering medications, achieving a mean IOP reduction of 34% from baseline at a dose of 78-mcg, with all patients reaching a best-corrected distance visual acuity of 20/32 or better.

Read More

SpyGlass Pharma Reports First Quarter 2026 Financial Results and Provides Corporate Updates

Read More
BIM-IOL System
open-angle glaucoma (OAG) or ocular hypertension (OHT)
Phase 1/2
2026-05-14

In the Phase 1/2 trial of the BIM-IOL System, 98% of participants were free from topical IOP-lowering medications, achieving a mean IOP reduction of 34% from baseline at a dose of 78-mcg, with all patients reaching a best-corrected distance visual acuity of 20/32 or better.

Read More

SpyGlass Pharma Reports First Quarter 2026 Financial Results and Provides Corporate Updates

Read More
BIM-IOL System
open-angle glaucoma (OAG) or ocular hypertension (OHT)
Phase 1/2
2026-05-14

In the Phase 1/2 trial of the BIM-IOL System, 98% of participants were free from topical IOP-lowering medications, achieving a mean IOP reduction of 34% from baseline at a dose of 78-mcg, with all patients reaching a best-corrected distance visual acuity of 20/32 or better.

Read More

SpyGlass Pharma Reports First Quarter 2026 Financial Results and Provides Corporate Updates

Read More
Unlock Clinical Trial Results data
Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
SGP Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
Unlock Option Chain Statistics data
Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
Unlock Option Chain data
Unlock Options Chart data
Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
SGP
Jun 15, 2026
SGPGeneral

SpyGlass Pharma Appoints Shannon Treviño as General Counsel

SpyGlass Pharma has appointed Shannon Treviño as General Counsel, bringing significant legal expertise to the company. Treviño's background includes leadership roles in corporate law and successful navigation of major acquisitions. Her appointment coincides with the advancement of SpyGlass's BIM-IOL System through Phase 3 clinical trials, aiming for potential commercialization.

Read more →
SGP
Jun 2, 2026
SGPGeneral

SpyGlass Pharma Appoints Mike Pinder as Vice President, Marketing

SpyGlass Pharma has appointed Mike Pinder as Vice President of Marketing, leveraging his extensive experience in ophthalmology. Pinder will lead marketing efforts as the company advances its BIM-IOL System through Phase 3 clinical trials. His background includes successful brand launches, which are expected to support the commercialization of the innovative drug delivery technology.

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SGP
May 21, 2026
SGPConferences/Events

SpyGlass Pharma to Participate in Upcoming Investor Conferences

SpyGlass Pharma, a late-stage biopharmaceutical company, announced its participation in several upcoming investor conferences, including the Stifel 2026 Virtual Ophthalmology Forum and the Jefferies Global Healthcare Conference. These events will feature presentations by the executive management team, highlighting the company's innovative drug delivery solutions for chronic eye conditions. Access to live webcasts will be available on their website.

Read more →
SGP
May 14, 2026
SGPPhases

SpyGlass Pharma Reports First Quarter 2026 Financial Results and Provides Corporate Updates

SpyGlass Pharma reported its Q1 2026 financial results, highlighting positive topline data from its Phase 1/2 trial of the BIM-IOL System, which showed significant intraocular pressure reduction. The company is on track to complete enrollment in its Phase 3 trials by 2027 and has a strong cash position to fund operations through 2028. The CEO emphasized the potential benefits of the BIM-IOL System for glaucoma patients.

Read more →
SGP
Mar 27, 2026
SGPGeneral
▼ -10.3%on this news

SpyGlass Pharma Reports Fourth Quarter and Full Year 2025 Earnings and Provides a Corporate Update

SpyGlass Pharma reported its fourth quarter and full year 2025 earnings, highlighting the initiation of two Phase 3 trials for its BIM-IOL System. The company achieved positive results in its Phase 1/2 trial, showing significant intraocular pressure reduction. Despite a net loss of $39.9 million, SpyGlass is well-funded following its IPO, which positions it for future growth.

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SGP
Mar 9, 2026
SGPPhases

SpyGlass Pharma Announces Positive Topline 12-Month Phase 1/2 Trial Results for Its Innovative BIM-IOL System

SpyGlass Pharma announced positive results from its Phase 1/2 trial of the BIM-IOL System, showing significant reductions in intraocular pressure (IOP) and improved visual acuity in patients with open-angle glaucoma or ocular hypertension. The trial demonstrated that 97% of patients were free from topical IOP-lowering medications after 12 months. Safety results were comparable to standard cataract surgery, indicating the system's potential for long-term treatment adherence.

Read more →
SGP
Mar 9, 2026
SGPPhases

amended. All statements in this press release that are not purely historical are forward-looking statements, including, but not limited to, statements regarding the potential benefits and impact of the BIM-IOL System on

SpyGlass Pharma announced positive 12-month results from its Phase 1/2 trial for the BIM-IOL System, indicating it effectively reduces elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. The trial included 104 patients, and results showed 97% were off all topical IOP-lowering medications, with 100% reaching at least 20/32 vision. Safety results were comparable to traditional cataract surgery, with no serious adverse events reported. The company is focused on advancing further trials towards potential commercial approval.

Read more →
SGP
Mar 4, 2026
SGPConferences/Events

SpyGlass Pharma to Participate in the Jefferies Biotech on the Beach Summit

SpyGlass Pharma, a late-stage biopharmaceutical company, will host one-on-one meetings at the Jefferies Biotech on the Beach Summit in Miami Beach on March 11, 2026. The company aims to improve treatment for chronic eye conditions through its innovative drug delivery platform, which utilizes approved medicines. Founded in 2019, SpyGlass Pharma focuses on durable solutions for eye care.

Read more →
SGP
Feb 10, 2026
SGPGeneral
▲ +6.3%on this news

SpyGlass Pharma Announces Closing of Initial Public Offering and Exercise in Full of the Underwriters’ Option to Purchase Additional Shares

SpyGlass Pharma has announced the successful closing of its initial public offering, raising $172.5 million by offering 10,781,250 shares at $16.00 each. This includes the full exercise of the underwriters' option to purchase additional shares. The company's stock began trading on Nasdaq under the ticker SGP on February 6, 2026.

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SGP
Feb 6, 2026
SGPGeneral

SpyGlass Pharma Announces Pricing of Initial Public Offering

SpyGlass Pharma has announced the pricing of its initial public offering, offering 9,375,000 shares at $16.00 each, aiming to raise around $150 million. The IPO is set to close on February 9, 2026, and the shares will begin trading on the Nasdaq Global Select Market on February 6, 2026. The company focuses on innovative treatments for chronic eye conditions.

Read more →
Competitive Position
How SGP ranks across every disease it competes in
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