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telbermin

Phase 2

Foot Ulcer, Diabetic | Small molecule | Metabolic |Roche Holding AG|Last Updated: Jan 25, 2013

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment170

FDA Designations

No designations recorded

Clinical trial landscape

telbermin · 1 trial · 1 indication

Phase 2 1
NCT00351767A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot UlcersFoot Ulcer, Diabetic
COMPLETED170 Analytics
PHASE2COMPLETED
A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
Foot Ulcer, DiabeticUnlock trial analytics

Study Endpoints

Primary Endpoints

Skin re-epithelialization without drainage or dressing requirements
12 weeks

Secondary Endpoints

Complete closure of the study ulcer
24 weeks
Durability of closure
Time to recurrence
Change and percent change in ulcer surface area
12 and 24 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -
2EXPERIMENTAL -
3EXPERIMENTAL -
4PLACEBO_COMPARATOR -

Interventions

NameTypeDescription
placeboDRUGTopically applied
telberminDRUGTopically applied
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Ability and willingness to comply with the following: study drug gel application and dressing changes as instructed; use offloading footwear and practice of rubbing prevention (shear injury) of the study ulcer for the duration of the study; adherence to study requirements or u...

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Frequently asked questions about telbermin

What is telbermin used for?

Telbermin is an investigational small molecule being developed for the treatment of diabetic foot ulcers. It is administered topically to induce healing of these ulcers. The drug is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes telbermin?

Telbermin is being developed by Roche Holding AG, which trades under the ticker RHHBY. The company is conducting clinical trials to evaluate the drug's safety and efficacy for diabetic foot ulcers.

What phase is telbermin in?

Telbermin is in Phase 2 clinical development. It is an investigational drug and has not yet received regulatory approval. A Phase 2 trial has been completed to assess its effect on healing diabetic foot ulcers.

What clinical trials is telbermin in?

Telbermin has one completed Phase 2 clinical trial, identified as NCT00351767. This study assessed the effect of topical recombinant human vascular endothelial growth factor for induction of healing of diabetic foot ulcers, enrolling 170 participants.

Is telbermin the same as recombinant human vascular endothelial growth factor?

Telbermin is a topical recombinant human vascular endothelial growth factor, as described in the clinical trial title. The study evaluates this agent for inducing healing of diabetic foot ulcers.