Recent Updates
Recently added Catalysts

Ropinirole

Phase 1

Healthy | Small molecule | Other |Dr. Reddy's Laboratories Ltd|Last Updated: Sep 28, 2012

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment96
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01627834Bioequivalence Study of Ropinirole Hydrochloride ER Tablets 2 mg Under Fasting ConditionPHASE1 COMPLETED 48Oct 1, 2009Nov 1, 2009Sep 28, 20121 India
NCT01627847Bioequivalence Study of Ropinirole Hydrochloride ER Tablets 2 mg Under Fed ConditionPHASE1 COMPLETED 48Oct 1, 2009Nov 1, 2009Sep 28, 20121 India
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Area under curve(AUC)
Pre-dose (before dosing, in the morning of the day of dosing) and at 1.00, 2.00, 3.00,4.00, 5.00, 6.00, 7.00, 8.00, 9.00, 10.00, 11.00, 12.00, 13.00, 14.00, 15.00, 16.00, 17.00, 18.00,20.00, 24.00, 30.00, 36.00, 48.00 and 60.00 hours after dosing.
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
RopiniroleEXPERIMENTALRopinirole Hydrochloride ER tablets 2 mg of Dr. Reddy's Laboratories Limited
RequipACTIVE_COMPARATORRequip XL Tablets 2 mg of Glaxosmithkline, USA
Interventions
NameTypeDescription
RopiniroleDRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Healthy human subjects aged between 18 and 45 years (including both). 2. Subjects with a BMI between 18.5 - 24.9 Kg/m2 (including both) but body weight not less than 45 Kgs. 3. Subjects with normal health as determined by personal medical history, clinical examination, and la...

Countries:India
Unlock Eligibility Criteria