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Mycophenolate Mofetil

Phase 1

FED | Small molecule | Metabolic |Dr. Reddy's Laboratories Ltd|Last Updated: Jan 20, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment92

FDA Designations

No designations recorded

Clinical trial landscape

Mycophenolate Mofetil · 4 trials · 3 indications

Phase 1 4
NCT01513044Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fasting ConditionsHealthy
COMPLETED68 Analytics
NCT01513057Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fed ConditionsHealthy
COMPLETED61 Analytics
NCT01283841Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Fasting ConditionsFasting
COMPLETED48 Analytics
NCT01283867Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Non-Fasting ConditionsFED
COMPLETED92 Analytics
PHASE1COMPLETED
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fed Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Fasting Conditions
FastingUnlock trial analytics
PHASE1COMPLETED
Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Non-Fasting Conditions
FEDUnlock trial analytics

Study Endpoints

Primary Endpoints

Area Under Curve (AUC)
Pre-dose, 0.083, 0.167, 0.25, 0.333, 0.41, 0.50, 0.667, 0.833, 1.00, 1.25, 1.50, 2.00, 2.50, 3.00, 4.00, 5.00, 6.00, 7.00, 8.00, 10.00, 12.00, 16.00, 24.00, 36.00, 48.00, 60.00 and 72.00 post dose
Bioequivalence on Cmax and AUC parameters
3 months
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Mycophenolate MofetilEXPERIMENTALMycophenolate Mofetil 250 mg capsules of Dr. Reddy's Laboratories Limited
CellceptACTIVE_COMPARATORCellcept 250 mg capsules of Roche Laboratories Inc.

Interventions

NameTypeDescription
Mycophenolate MofetilDRUGMycophenolate Mofetil 250 mg capsules of Dr. Reddy's Laboratories Limited
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Subjects aged between 18 and 50 years (including both). * Subjects' weight within the normal range according to normal values for the Body * Mass Index (1 8.5 to 24.9 kg/m2) with minimum of 50 kg weight. * Subjects with clinically acceptable normal health as determined by pers...

Countries:India
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Frequently asked questions about Mycophenolate Mofetil

What is Mycophenolate Mofetil used for?

Mycophenolate Mofetil is being studied in healthy volunteers under fasting and fed conditions. It is an investigational small molecule in Phase 1 clinical development for metabolic conditions. Dr. Reddy's Laboratories Ltd is conducting bioequivalence studies to compare different tablet and capsule formulations of the drug.

Who makes Mycophenolate Mofetil?

Dr. Reddy's Laboratories Ltd (ticker: RDY) is developing Mycophenolate Mofetil. The company has completed Phase 1 bioequivalence studies for both 500 mg tablets and 250 mg capsules of the drug in healthy volunteers in India.

What phase is Mycophenolate Mofetil in?

Mycophenolate Mofetil is in Phase 1 clinical development. It is an investigational drug, not yet approved by regulatory authorities. Dr. Reddy's Laboratories Ltd has completed two Phase 1 bioequivalence studies for the 500 mg tablet and two for the 250 mg capsule formulations.

What clinical trials is Mycophenolate Mofetil in?

Mycophenolate Mofetil has completed four Phase 1 trials. NCT01283841 studied 500 mg tablets under fasting conditions in 48 male participants. NCT01283867 studied 500 mg tablets under fed conditions in 92 male participants. NCT01513044 studied 250 mg capsules fasting in 68 participants, and NCT01513057 studied 250 mg capsules fed in 61 participants.

Is Mycophenolate Mofetil the same as CellCept?

Mycophenolate Mofetil is the generic name for the drug also known as CellCept. Dr. Reddy's Laboratories Ltd is developing generic versions of this drug, including 500 mg tablets and 250 mg capsules, which are being tested for bioequivalence to the reference product.